KEGG   ORTHOLOGY: K16876
Entry
K16876                      KO                                     
Symbol
hmfD
Name
2-furoate---CoA ligase [EC:6.2.1.31]
Pathway
map00365  Furfural degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00365 Furfural degradation
    K16876  hmfD; 2-furoate---CoA ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.31  2-furoate---CoA ligase
     K16876  hmfD; 2-furoate---CoA ligase
Other DBs
RN: R02986
GO: 0047541
Genes
PPSE: BN5_2301(hmfD)
PMAN: OU5_0886
PSTT: CH92_11545
PPUU: PputUW4_02622
PSIL: PMA3_09785
PALL: UYA_10525
CSA: Csal_2523
HSV: HNO53_04210
ADI: B5T_02848
RPI: Rpic_2055
REH: H16_A1700(h16_A1700)
BXE: Bxe_A2076
BXB: DR64_4231
BPH: Bphy_6670
BFN: OI25_3191
CABA: SBC2_58980(fcbA2)
AMIM: MIM_c34410
ODI: ODI_R0531
HPSE: HPF_15735(fcbA2)
BJA: blr3536(blr3536)
BARH: WN72_17970
RPC: RPC_0851
MET: M446_1304
MNO: Mnod_3299
MOR: MOC_3636
MAQU: Maq22A_c13980(caiC)
DSH: Dshi_3722
ACR: Acry_0671
GKA: GKP17 GKP25
GGH: GHH_c13600(menE1)
ANM: GFC28_301
AAD: TC41_0787
PDX: Psed_5934
PSEA: WY02_08315
PSEE: FRP1_29380
PAUT: Pdca_67720
AG: ADE20402(hmfD)
 » show all
Reference
  Authors
Koopman F, Wierckx N, de Winde JH, Ruijssenaars HJ
  Title
Identification and characterization of the furfural and 5-(hydroxymethyl)furfural degradation pathways of Cupriavidus basilensis HMF14.
  Journal
Proc Natl Acad Sci U S A 107:4919-24 (2010)
DOI:10.1073/pnas.0913039107
  Sequence
LinkDB

KEGG   ENZYME: 6.2.1.31
Entry
EC 6.2.1.31                 Enzyme                                 
Name
2-furoate---CoA ligase;
2-furoyl coenzyme A synthetase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
Sysname
2-furoate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + 2-furoate + CoA = AMP + diphosphate + 2-furoyl-CoA [RN:R02986]
Reaction(KEGG)
R02986
Substrate
ATP [CPD:C00002];
2-furoate [CPD:C01546];
CoA [CPD:C00010]
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
2-furoyl-CoA [CPD:C00845]
History
EC 6.2.1.31 created 1992
Pathway
ec00365  Furfural degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16876  2-furoate---CoA ligase
Genes
PPSEBN5_2301(hmfD)
PMANOU5_0886
PSTTCH92_11545
PPUUPputUW4_02622
PSILPMA3_09785
PALLUYA_10525
CSACsal_2523
HSVHNO53_04210
ADIB5T_02848
RPIRpic_2055
RPFRpic12D_1747
RPJN234_37075
REHH16_A1700(h16_A1700)
CUHBJN34_36270
REUReut_C5887
COXE0W60_18625 E0W60_32405
BUGBC1001_3786
BGFBC1003_0593
BYIBYI23_A013010
BUQAC233_20835
BUMAXG89_18110
BUIAX768_27885
BXEBxe_A2076
BXBDR64_4231
BPHBphy_6670
BGEBC1002_5744
BPXBUPH_00360
BPYBphyt_2182
BUZAYM40_12160
BFNOI25_3191
BCAIK788_0001304
PARBCJU94_33595
PHSC2L64_39395
PTERC2L65_36675
PGPCUJ91_22590
PCJCUJ87_08675
PDQCL55_00008540
CABASBC2_58980(fcbA2)
BBROBAU06_03110 BAU06_14960
BFZBAU07_13305 BAU07_17235
AMIMMIM_c34410
ODIODI_R0531
PIGEGT29_14615
ACKC380_16240 C380_21255
HPSEHPF_15735(fcbA2)
ATWC0099_09880
DWDDSCW_52460
ORMHTY61_00455
KMNHW532_18845
EAKEKH55_3889
ABAWD5400_18150
BJAblr3536(blr3536)
BJUBJ6T_61940
BJPRN69_30005
BOTCIT37_36535
BGQX265_16180
BARHWN72_17970
RPCRPC_0851
BOSBSY19_1057
BVVBHK69_28565
XDIEZH22_10475
MRDMrad2831_4726
METM446_1304
MNOMnod_3299
MORMOC_3636
MAQUMaq22A_c13980(caiC)
MPHYMCBMB27_05475
MEEDA075_33375
METXA3862_05000
METIDK427_10975
RHZRHPLAN_46400
PSINCAK95_25390
DSHDshi_3722
PABYGa0080574_TMP3696
SULDB5M07_03655
SPOTG6548_00065
PTPRCA23_c12050
CMAGCBW24_14185
ACRAcry_0671
AMVACMV_11980
AZLAZL_a10990
ATIAL072_24285
AOZHUE56_07970
BACQDOE78_11810
GKAGKP17 GKP25
GMCGY4MC1_2421
GGHGHH_c13600(menE1)
PTLAOT13_10320
PCALBV455_00384
ANMGFC28_301
ANLGFC29_1323
APAKAP3564_10415
SHVAAT16_04545 AAT16_04560
PNPIJ22_36500 IJ22_36580
AADTC41_0787
EFFskT53_32190 skT53_32260
SVLStrvi_4350
SRCM271_02675
AMQAMETH_3078
AACDLWP59_20660
PDXPsed_5934
PSEAWY02_08315
PSEEFRP1_29380
PECQAD017_32255
PAUTPdca_67720
PBROHOP40_06550
HALUHUG12_20130
HMPK6T50_15985 K6T50_16005
HREK6T36_15885 K6T36_15905
NVRFEJ81_19715 FEJ81_19735
 » show all
Reference
1  [PMID:16347977]
  Authors
Koenig K, Andreesen JR.
  Title
Molybdenum Involvement in Aerobic Degradation of 2-Furoic Acid by Pseudomonas putida Fu1.
  Journal
Appl Environ Microbiol 55:1829-1834 (1989)
DOI:10.1128/AEM.55.7.1829-1834.1989
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.31
IUBMB Enzyme Nomenclature: 6.2.1.31
ExPASy - ENZYME nomenclature database: 6.2.1.31
UM-BBD (Biocatalysis/Biodegradation Database): 6.2.1.31
BRENDA, the Enzyme Database: 6.2.1.31
CAS: 122320-08-5
LinkDB

KEGG   REACTION: R02986
Entry
R02986                      Reaction                               
Name
2-furoate:CoA ligase (AMP-forming)
Definition
ATP + 2-Furoate + CoA <=> AMP + Diphosphate + 2-Furoyl-CoA
Equation
Reaction class
RC00004  C00010_C00845
RC00174  C00845_C01546
Enzyme
Pathway
rn00365  Furfural degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K16876  2-furoate---CoA ligase [EC:6.2.1.31]
Other DBs
RHEA: 19272
LinkDB

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