ORTHOLOGY: K17698
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Entry
K17698 KO
Symbol
FYB, ADAP
Name
FYN binding protein
Pathway
map04015
Rap1 signaling pathway
map05135
Yersinia infection
Disease
H00978
Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
K17698 FYB, ADAP; FYN binding protein
09160 Human Diseases
09171 Infectious disease: bacterial
05135 Yersinia infection
K17698 FYB, ADAP; FYN binding protein
BRITE hierarchy
Genes
HSA:
2533
(FYB1)
PTR:
461906
(FYB1)
PPS:
100973132
(FYB1)
GGO:
101130496
(FYB1)
PON:
100440675
(FYB1)
PPYG:
129037353
(FYB1)
NLE:
100592360
(FYB1)
HMH:
116456837
(FYB1)
SSYN:
129464709
(FYB1)
MCC:
693951
(FYB1)
MCF:
101867044
(FYB1)
MTHB:
126956446
MNI:
105473108
(FYB1)
CSAB:
103215164
(FYB)
CATY:
105583453
(FYB)
PANU:
101009417
(FYB1)
TGE:
112626773
(FYB1)
MLEU:
105529104
(FYB)
RRO:
104665749
(FYB1)
RBB:
108515993
(FYB)
TFN:
117065048
(FYB1)
PTEH:
111545497
(FYB1)
CANG:
105513517
(FYB)
CJC:
100411367
(FYB1)
SBQ:
101034501
(FYB)
CIMI:
108287472
(FYB1)
ANAN:
105722506
(FYB1)
CSYR:
103269063
(FYB1)
MMUR:
105855475
(FYB)
LCAT:
123648482
(FYB1)
PCOQ:
105814521
(FYB)
OGA:
100962684
(FYB1)
MMU:
23880
(Fyb1)
MCAL:
110310521
(Fyb1)
MPAH:
110329072
(Fyb)
RNO:
499537
(Fyb1)
MCOC:
116083931
(Fyb1)
ANU:
117723975
(Fyb1)
MUN:
110563626
(Fyb1)
CGE:
100774387
(Fyb1)
MAUA:
101834385
(Fyb1)
PROB:
127220618
(Fyb1)
PLEU:
114697345
(Fyb1)
MORG:
121432906
(Fyb1)
MFOT:
126499663
AAMP:
119808933
(Fyb1)
NGI:
103741332
(Fyb)
HGL:
101718443
(Fyb)
CPOC:
100715602
(Fyb1)
CCAN:
109688331
(Fyb)
DORD:
105987388
(Fyb)
DSP:
122116961
(Fyb1)
PLOP:
125367462
(Fyb1)
NCAR:
124987296
MMMA:
107151103
(Fyb1)
OCU:
100350748
(FYB1)
OPI:
101521308
(FYB1)
TUP:
102486641
(FYB)
GVR:
103587102
(FYB)
CFA:
479355
(FYB1)
CLUD:
112652765
(FYB1)
VVP:
112933536
(FYB1)
VLG:
121486496
(FYB1)
NPO:
129509338
(FYB1)
AML:
100464552
(FYB1)
UMR:
103664684
(FYB1)
UAH:
113260918
(FYB1)
UAR:
123785501
(FYB1)
ELK:
111140907
LLV:
125100567
MPUF:
101672828
(FYB)
MNP:
132028263
(FYB1)
MLK:
131831684
(FYB1)
NVS:
122894936
(FYB1)
ORO:
101376339
(FYB)
EJU:
114204783
(FYB1)
ZCA:
113929678
(FYB1)
MLX:
118006343
118006474
NSU:
110586169
(FYB1)
LWW:
102736488
(FYB1)
FCA:
101095954
(FYB1)
PYU:
121043861
(FYB1)
PCOO:
112861142
(FYB1)
PBG:
122494392
(FYB1)
PVIV:
125168032
(FYB1)
LRUF:
124522045
PTG:
102958889
(FYB)
PPAD:
109275832
(FYB)
PUC:
125935029
AJU:
106970917
(FYB1)
HHV:
120239787
(FYB1)
BTA:
535347
(FYB1)
BOM:
102276797
(FYB)
BIU:
109574977
(FYB)
BBUB:
102396598
(FYB1)
BBIS:
104998534
(FYB)
CHX:
102190820
(FYB)
OAS:
101105278
(FYB1)
BTAX:
128066018
(FYB1)
ODA:
120879363
(FYB1)
CCAD:
122454427
(FYB1)
MBEZ:
129553304
(FYB1)
SSC:
100520112
(FYB)
CFR:
102507177
(FYB1)
CBAI:
105070693
(FYB)
CDK:
105106853
(FYB1)
VPC:
102534419
(FYB1)
BACU:
102999137
(FYB)
BMUS:
118891780
(FYB1)
LVE:
103080786
(FYB)
OOR:
101289702
(FYB1)
DLE:
115801623
PCAD:
102977067
(FYB1)
PSIU:
116751202
(FYB1)
NASI:
112405975
(FYB1)
ECB:
100066754
(FYB1)
EPZ:
103555258
(FYB)
EAI:
106824738
(FYB1)
MYB:
102256105
(FYB)
MYD:
102766248
(FYB)
MMYO:
118655849
(FYB1)
MLF:
102434394
(FYB1)
MDT:
132233742
(FYB1)
PKL:
118703774
(FYB1)
EFUS:
103298836
(FYB1)
MNA:
107545673
(FYB)
DRO:
112321077
(FYB1)
SHON:
118998794
(FYB1)
AJM:
119044258
(FYB1)
PDIC:
114506429
114511450
(FYB1)
PHAS:
123824858
(FYB1)
MMF:
118642346
(FYB1)
PPAM:
129079001
(FYB1)
HAI:
109387051
(FYB)
RFQ:
117025238
(FYB1)
PALE:
102885526
(FYB1)
PGIG:
120586168
(FYB1)
PVP:
105299100
(FYB1)
RAY:
107512431
(FYB)
MJV:
108388561
(FYB1)
TOD:
119260952
(FYB1)
SARA:
101543288
(FYB)
SETR:
125999964
(FYB1)
LAV:
100667296
(FYB1)
TMU:
101348301
DNM:
101447475
(FYB1)
MDO:
100019146
(FYB)
GAS:
123237352
(FYB1)
SHR:
100933793
(FYB1)
AFZ:
127556772
PCW:
110214964
(FYB)
TVP:
118854958
(FYB1)
OAA:
100076091
(FYB1)
GGA:
427448
(FYB)
PCOC:
116229817
(FYB1)
MGP:
104914850
(FYB1)
CJO:
107305868
(FYB1)
TPAI:
128074469
(FYB1)
LMUT:
125686596
(FYB1)
NMEL:
110389803
(FYB1)
ACYG:
106036336
(FYB1)
CATA:
118256657
(FYB1)
AFUL:
116500738
(FYB1)
TGU:
100226200
(FYB1)
LSR:
110482693
(FYB1)
SCAN:
103821073
(FYB1)
PMOA:
120502531
(FYB1)
OTC:
121331523
(FYB1)
PRUF:
121356329
(FYB1)
GFR:
102038511
(FYB)
FAB:
101811935
(FYB)
OMA:
130265199
(FYB1)
PHI:
102108162
(FYB)
PMAJ:
107198349
(FYB1)
CCAE:
111941411
(FYB1)
CCW:
104686622
(FYB1)
CBRC:
103612931
(FYB)
ETL:
114055017
(FYB1)
ZAB:
102066669
(FYB1)
ZLE:
135459453
(FYB1)
SVG:
106852754
(FYB)
MMEA:
130572784
(FYB1)
HRT:
120765679
(FYB1)
SATI:
136373627
(FYB1)
FPG:
101914294
(FYB)
FCH:
102050080
(FYB1)
CCRI:
104166369
NNT:
104410987
(FYB)
SHAB:
115600565
(FYB1)
ACUN:
113489910
(FYB1)
TALA:
104357693
(FYB1)
ACHC:
115337181
(FYB1)
HALD:
104322605
(FYB)
HLE:
104843079
(FYB)
AGEN:
126035814
GCL:
127027216
127028196
CSTI:
104561793
(FYB)
LDI:
104342651
(FYB)
MNB:
103769323
(FYB)
DPUB:
104299328
(FYB)
AVIT:
104270534
(FYB)
BRHI:
104490956
(FYB)
EGZ:
104133862
(FYB)
NNI:
104009182
(FYB)
PCRI:
104027523
(FYB)
PCAO:
104049279
(FYB)
PADL:
103921460
(FYB)
AFOR:
103903865
(FYB)
FGA:
104081674
(FYB)
GSTE:
104265099
(FYB)
CLV:
102087048
(FYB)
MUI:
104541068
(FYB)
PLET:
104628483
EHS:
104507705
(FYB)
CMAC:
104478105
CUCA:
104059665
(FYB1)
TEO:
104384271
(FYB)
BREG:
104634162
(FYB)
OHA:
104337684
(FYB)
ACAR:
104524656
(FYB1)
CPEA:
104398617
(FYB)
CVF:
104294975
(FYB)
RTD:
128902529
(FYB1)
AAM:
106499518
(FYB)
AROW:
112962173
(FYB1)
NPD:
112946070
(FYB1)
TGT:
104566112
104579052
(FYB)
DNE:
112983602
(FYB1)
SCAM:
104147797
(FYB)
ASN:
102380576
(FYB1)
AMJ:
102558591
(FYB)
CPOO:
109307852
(FYB)
GGN:
109297877
(FYB)
PSS:
102463369
(FYB1)
CMY:
102945202
(FYB1)
CCAY:
125637069
(FYB1)
DCC:
119856210
(FYB1)
CPIC:
101942775
(FYB1)
TST:
117879493
(FYB1)
CABI:
116820521
(FYB1)
MRV:
120408180
(FYB1)
ACS:
100568035
(fyb)
ASAO:
132766941
(FYB1)
PVT:
110080081
(FYB)
SUND:
121921723
(FYB1)
PBI:
103058644
(FYB1)
PMUR:
107288269
(FYB1)
CTIG:
120310037
(FYB1)
TSR:
106546500
(FYB)
PGUT:
117679138
(FYB1)
APRI:
131192137
(FYB1)
PTEX:
113446314
(FYB1)
NSS:
113411392
(FYB1)
VKO:
123024040
(FYB1)
PMUA:
114606655
(FYB1)
PRAF:
128423311
(FYB1)
ZVI:
118077262
(FYB1)
HCG:
128347241
(FYB1)
GJA:
107117964
(FYB)
STOW:
125437250
(FYB1)
EMC:
129334783
(FYB1)
XLA:
108707306
108714247
108715540
108718404
XTR:
100485737
(fyb1)
100493579
(fyb2)
NPR:
108785338
(FYB)
RTEM:
120927746
(FYB1)
120946100
(FYB2)
BBUF:
120979869
(FYB2)
120992165
(FYB1)
BGAR:
122944151
(FYB2)
MUO:
115462953
(FYB1)
GSH:
117354615
(FYB1)
DRE:
796938
(fyb1b)
SRX:
107706487
107725075
107750297
107750395
SANH:
107658239
107681167
107703588
107704867
SGH:
107567647
107589243
107591708
CCAR:
109101145
109104717
CAUA:
113038726
113064211
113067976
113072927
CGIB:
127941451
127986654
PTET:
122326236
(fybb)
LROH:
127152253
(fybb)
OMC:
131528253
(fybb)
PPRM:
120490707
(fybb)
RKG:
130102264
(fybb)
MAMB:
125252567
(fybb)
CIDE:
127503678
CERY:
137013030
(fyb1b)
MASI:
127428873
127431302
TROS:
130569999
(fybb)
TDW:
130408162
(fybb)
MANU:
129423435
(fybb)
IPU:
108268214
(si:ch211-188c16.1)
108271407
(si:ch73-40i7.2)
108278849
(fybb)
IFU:
128622006
(fybb)
PHYP:
113543234
(fyb1)
113547285
SMEO:
124376693
124397955
(fybb)
TFD:
113638587
(fybb)
TVC:
132859707
(fyb1b)
TRN:
134330767
(fyb1b)
AMEX:
103022200
(si:ch211-188c16.1)
103030081
(fybb)
103040774
(si:ch73-40i7.2)
CMAO:
118819707
(fybb)
EEE:
113570770
(fyb1)
113581901
CHAR:
122133025
TRU:
101066390
101069740
(fyb1)
101070379
105417906
TFS:
130516893
(fybb)
130528360
(si:ch73-40i7.2)
130529114
130538898
(si:ch211-188c16.1)
TNG:
GSTEN00009153G001
GSTEN00011528G001
GSTEN00015041G001
GSTEN00017352G001
LCO:
104923493
(fyb1)
104928406
104932766
(fyb2)
NCC:
104945623
104946395
104957205
104962342
(fyb)
TBEN:
117476510
(fybb)
117488390
(si:ch211-188c16.1)
117495945
(si:ch73-40i7.2)
117496027
CGOB:
115007541
115016546
115022598
PGEO:
117444926
(si:ch73-40i7.2)
117445896
117456214
(fybb)
117462547
(si:ch211-188c16.1)
GACU:
117535913
(fybb)
117544223
(si:ch73-40i7.2)
117545572
(si:ch211-188c16.1)
117555088
EMAC:
134865593
(si:ch211-188c16.1)
134868338
(fyb1b)
134869080
(si:ch73-40i7.2)
134869924
ELY:
117253341
117254470
(si:ch73-40i7.2)
117270091
(fybb)
117271785
(si:ch211-188c16.1)
EFO:
125895749
(si:ch73-40i7.2)
125895918
125901568
(si:ch211-188c16.1)
125906036
(fybb)
PLEP:
121941160
(si:ch73-40i7.2)
121941325
121959767
(fybb)
SLUC:
116035001
(fybb)
116045573
(si:ch211-188c16.1)
116055369
(si:ch73-40i7.2)
116058892
ECRA:
117951111
(si:ch73-40i7.2)
117954278
(si:ch211-188c16.1)
117958962
(fybb)
ESP:
116694936
116695933
116699215
116703905
(fyb1)
PFLV:
114561546
114562144
114565900
114570659
(fyb1)
GAT:
120815684
(si:ch211-188c16.1)
120823596
(si:ch73-40i7.2)
120832234
(fybb)
PPUG:
119209902
(si:ch211-188c16.1)
119216477
(si:ch73-40i7.2)
119216660
119226508
(fybb)
AFB:
129089208
(si:ch211-188c16.1)
129095003
(si:ch73-40i7.2)
129102539
(fybb)
CLUM:
117729565
(si:ch73-40i7.2)
117740225
(fybb)
117746671
(si:ch211-188c16.1)
PSWI:
130194403
(si:ch73-40i7.2)
130198191
(si:ch211-188c16.1)
130205770
(fybb)
MSAM:
119900521
(si:ch73-40i7.2)
119901029
119902408
(si:ch211-188c16.1)
119914360
(fybb)
SCHU:
122866073
(fybb)
122877155
122878149
(si:ch73-40i7.2)
122887575
(si:ch211-188c16.1)
CUD:
121511922
(si:ch73-40i7.2)
121519592
(si:ch211-188c16.1)
121525569
(fybb)
ALAT:
119011423
(si:ch211-188c16.1)
119028668
119030056
(fybb)
MZE:
101464838
101467123
101475547
ONL:
100694531
100700900
102077259
102078195
OAU:
116314161
(si:ch211-188c16.1)
116316889
(si:ch73-40i7.2)
116331302
116335192
(fybb)
OLA:
101164547
101169029
101169301
(fyb1)
101172194
OML:
112147771
(si:ch211-188c16.1)
112150736
(si:ch73-40i7.2)
112155785
112163418
(fybb)
CSAI:
133455306
(fyb1b)
133458312
133458535
(si:ch73-40i7.2)
XMA:
102229695
(fyb1)
102231106
111609755
XCO:
114145895
114149409
(fyb1)
114151463
XHE:
116721888
116724230
(fyb1)
116725525
(fyb2)
116726390
PRET:
103463235
103473657
(fyb)
103478977
PFOR:
103140043
103148155
(fyb)
103153758
PLAI:
106939269
106946429
(fyb)
106946524
106952590
PMEI:
106907140
106915607
(fyb)
106929347
GAF:
122838134
(si:ch73-40i7.2)
122838437
122841465
(si:ch211-188c16.1)
122846920
(fybb)
PPRL:
129361679
(si:ch211-188c16.1)
129366388
(fybb)
129373516
129375827
(si:ch73-40i7.2)
CVG:
107083613
107089792
(fyb)
107095191
CTUL:
119772376
119779316
(si:ch211-188c16.1)
119782645
(fybb)
119789846
(si:ch73-40i7.2)
GMU:
124869684
(si:ch211-188c16.1)
124872603
(fybb)
124873886
(si:ch73-40i7.2)
NFU:
107372660
(fyb)
107384446
107392791
KMR:
108232551
(fybb)
108234282
(si:ch73-40i7.2)
108238242
(si:ch211-188c16.1)
ALIM:
106514533
(fyb)
106519228
106521304
NWH:
119425138
(fybb)
AOCE:
111567110
(fyb1)
111584557
111587391
MCEP:
124997073
(fybB)
125009164
125009667
(si:ch73-40i7.2)
125010457
CSEM:
103376654
(c2h1orf168)
103389113
103395843
103396192
POV:
109626008
(fyb)
109636591
109637239
SSEN:
122758150
(fybb)
122777762
(si:ch211-188c16.1)
122780432
(si:ch73-40i7.2)
122780664
HHIP:
117760447
(si:ch73-40i7.2)
117760636
117771982
(fybb)
117778216
(si:ch211-188c16.1)
HSP:
118117816
(si:ch211-188c16.1)
118120637
(si:ch73-40i7.2)
118120707
118126009
(fybb)
PPLT:
128424744
(fybb)
128447861
128448420
(si:ch73-40i7.2)
128454965
(si:ch211-188c16.1)
SMAU:
118284485
(fybb)
118311070
(si:ch211-188c16.1)
118317664
(si:ch73-40i7.2)
118318670
LCF:
108877451
(si:ch73-40i7.2)
108879063
108879272
(fybb)
108883847
(si:ch211-188c16.1)
SDU:
111228898
111234240
(fyb1)
111240029
SLAL:
111651521
111666519
111669982
XGL:
120790297
(si:ch73-40i7.2)
120798734
(si:ch211-188c16.1)
120806650
(fybb)
HCQ:
109517092
109520610
109532066
SSCV:
125980050
125985421
(si:ch211-188c16.1)
SBIA:
133491015
(fyb1b)
133503619
(si:ch73-40i7.2)
133510748
(si:ch211-188c16.1)
PEE:
133406813
(si:ch73-40i7.2)
133414196
(fyb1b)
PTAO:
133481386
(si:ch73-40i7.2)
133488716
(si:ch211-188c16.1)
133490372
(fyb1b)
BPEC:
110162828
110173425
110174194
MALB:
109962061
109963427
(fyb)
109966841
109970665
BSPL:
114845020
(si:ch211-188c16.1)
114854509
(si:ch73-40i7.2)
114854737
114866781
(fybb)
SJO:
128362397
(si:ch73-40i7.2)
128369591
(si:ch211-188c16.1)
128380592
(fybb)
SASA:
100195010
(fyb)
106563559
106569300
106573888
106580587
106613992
STRU:
115149258
115151691
115157239
115159320
115200414
OTW:
112219554
(fybb)
112250749
112257511
112260677
(si:ch211-188c16.1)
112262632
OMY:
110494533
110523801
(fybb)
110524161
110524513
110530524
(si:ch211-188c16.1)
110536305
110537126
OGO:
123996874
123997419
123998198
(si:ch73-40i7.2)
124009210
(si:ch211-188c16.1)
124038662
124048731
ONE:
115105886
115107379
115109158
115114606
115125898
115140286
OKI:
109868040
109875381
109889133
109892467
109896125
109898000
109901534
OKE:
118358519
118371673
118374499
(si:ch211-188c16.1)
118387751
(fybb)
118388367
118391450
118401452
(si:ch73-40i7.2)
SALP:
111953076
111956488
111958240
111961393
111975620
111979906
SNH:
120026504
(fybb)
120044228
120053724
(si:ch73-40i7.2)
120055998
(si:ch211-188c16.1)
120062923
CCLU:
121535567
(si:ch211-188c16.1)
121573901
121576860
(si:ch73-40i7.2)
121582213
(fybb)
ELS:
105014414
105014733
105029291
109615648
SFM:
108923467
108930550
108932686
108934962
108938009
PKI:
111834802
111842255
(fyb1)
111847569
111856512
111860401
(pram1)
AANG:
118212925
(fybb)
118237264
LOC:
102698876
(fyb)
107078417
(clg10h1orf168)
PSPA:
121301319
(si:ch73-40i7.2)
121304936
121318492
121330525
ARUT:
117401292
117408555
117409499
117417021
117420389
117966312
LCM:
102355941
(FYB)
RTP:
109917951
CPLA:
122556423
HOC:
132826430
LERI:
129695276
BFO:
118431404
BBEL:
109475139
CIN:
100186459
APLC:
110985799
CSCU:
111626210
LGI:
LOTGIDRAFT_158006
HRF:
124114498
HRJ:
124291930
CRG:
105331421
PMAX:
117325767
OSN:
115215573
NVE:
5502232
5515876
EPA:
110248470
PDAM:
113682906
SPIS:
111323143
» show all
Taxonomy
UniProt
Reference
PMID:
9207119
Authors
da Silva AJ, Li Z, de Vera C, Canto E, Findell P, Rudd CE
Title
Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production.
Journal
Proc Natl Acad Sci U S A 94:7493-8 (1997)
DOI:
10.1073/pnas.94.14.7493
Sequence
[hsa:
2533
]
Reference
PMID:
12670399
Authors
Peterson EJ
Title
The TCR ADAPts to integrin-mediated cell adhesion.
Journal
Immunol Rev 192:113-21 (2003)
DOI:
10.1034/j.1600-065X.2003.00026.x
LinkDB
All DBs
DBGET
integrated database retrieval system