KEGG   ORTHOLOGY: K17898
Entry
K17898                      KO                                     
Symbol
oraE
Name
D-ornithine 4,5-aminomutase subunit beta [EC:5.4.3.5]
Pathway
map00470  D-Amino acid metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K17898  oraE; D-ornithine 4,5-aminomutase subunit beta
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.3  Transferring amino groups
    5.4.3.5  D-ornithine 4,5-aminomutase
     K17898  oraE; D-ornithine 4,5-aminomutase subunit beta
Other DBs
RN: R02461
GO: 0047831
Genes
EAV: EH197_05070
VCP: H9L18_06420
VHY: G7082_14515
CSQ: CSCA_0124
CACE: CACET_c17520(oraE)
CEU: A7L45_16575
CFM: BJL90_14535
CARG: RSJ17_08695
CDRK: B9W14_17920
AMT: Amet_2371
AOE: Clos_1695
CDF: CD630_04460(oraE)
PDC: CDIF630_00574(oraE)
CDC: CD196_0403(oraE)
CDL: CDR20291_0389(oraE)
PDF: CD630DERM_04460(oraE)
CST: CLOST_1290(oraE)
TEB: T8CH_0877(oraE)
AACX: DEACI_0850
ETM: CE91St48_39700(oraE)
TTE: TTE1238(Sbm3)
THX: Thet_1422
TOC: Toce_1485
NCD: ACONDI_00604(oraE)
KME: H0A61_00507(oraE)
PFT: JBW_01656
MANR: MPAN_008600(oraE)
MBJ: KQ51_00243(oraE)
PAC: PPA2280
PACC: PAC1_11630
CACN: RN83_00030
ABAT: CFX1CAM_0749(oraE)
TME: Tmel_0909
TAF: THA_1164
THER: Y592_05365
FNO: Fnod_1642
FIA: NA23_09995(oraE)
OCY: OSSY52_03940(oraE)
PMO: Pmob_1170
MARN: LN42_08190
DTN: DTL3_0763(oraE)
KOL: Kole_0360
MINF: MESINF_2280(oraE)
ASAC: ATHSA_0993
 » show all
Reference
  Authors
Wolthers KR, Levy C, Scrutton NS, Leys D
  Title
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
  Journal
J Biol Chem 285:13942-50 (2010)
DOI:10.1074/jbc.M109.068908
  Sequence
LinkDB

KEGG   ORTHOLOGY: K17899
Entry
K17899                      KO                                     
Symbol
oraS
Name
D-ornithine 4,5-aminomutase subunit alpha [EC:5.4.3.5]
Pathway
map00470  D-Amino acid metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K17899  oraS; D-ornithine 4,5-aminomutase subunit alpha
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.3  Transferring amino groups
    5.4.3.5  D-ornithine 4,5-aminomutase
     K17899  oraS; D-ornithine 4,5-aminomutase subunit alpha
Other DBs
RN: R02461
GO: 0047831
Genes
CBOT: ATE48_03355
EAV: EH197_05065
VCP: H9L18_06415
VHY: G7082_14520
CSQ: CSCA_0123
CACE: CACET_c17510(oraS)
CEU: A7L45_16580
CFM: BJL90_14530
CARG: RSJ17_08690
CDRK: B9W14_17925
AMT: Amet_2370
AOE: Clos_1696
CDF: CD630_04450(oraS)
PDC: CDIF630_00573(oraS)
CDC: CD196_0402(oraS)
CDL: CDR20291_0388(oraS)
PDF: CD630DERM_04450(oraS)
CST: CLOST_1291(oraS)
TEB: T8CH_0876(oraS)
AACX: DEACI_0849
ETM: CE91St48_39710(oraS)
TTE: TTE1237
THX: Thet_1423
TOC: Toce_1486
NCD: ACONDI_00603(oraS)
KME: H0A61_00508(oraS)
PFT: JBW_01655
MANR: MPAN_008590(oraS)
MBJ: KQ51_00244(oraS)
PAC: PPA2279
PACC: PAC1_11625
PACH: PAGK_2188
CACN: RN83_00025
ABAT: CFX1CAM_0748(oraS)
TME: Tmel_0908
TAF: THA_1163
THER: Y592_05360
FNO: Fnod_1643
OCY: OSSY52_03930(oraS)
PMO: Pmob_1169
MARN: LN42_08185
DTN: DTL3_0762
KOL: Kole_0359
MINF: MESINF_2281(oraS)
ASAC: ATHSA_0994
 » show all
Reference
  Authors
Wolthers KR, Levy C, Scrutton NS, Leys D
  Title
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
  Journal
J Biol Chem 285:13942-50 (2010)
DOI:10.1074/jbc.M109.068908
  Sequence
LinkDB

KEGG   ENZYME: 5.4.3.5
Entry
EC 5.4.3.5                  Enzyme                                 
Name
D-ornithine 4,5-aminomutase;
D-alpha-ornithine 5,4-aminomutase;
D-ornithine aminomutase
Class
Isomerases;
Intramolecular transferases;
Transferring amino groups
Sysname
D-ornithine 4,5-aminomutase
Reaction(IUBMB)
D-ornithine = (2R,4S)-2,4-diaminopentanoate [RN:R02461]
Reaction(KEGG)
R02461
Substrate
D-ornithine [CPD:C00515]
Product
(2R,4S)-2,4-diaminopentanoate [CPD:C03943]
Comment
A pyridoxal-phosphate protein that requires a cobamide coenzyme for activity.
History
EC 5.4.3.5 created 1972 as EC 5.4.3.1, transferred 1976 to EC 5.4.3.5, modified 2003
Pathway
ec00470  D-Amino acid metabolism
ec01100  Metabolic pathways
Orthology
K17898  D-ornithine 4,5-aminomutase subunit beta
K17899  D-ornithine 4,5-aminomutase subunit alpha
Genes
CBOTATE48_03355
EAVEH197_05065 EH197_05070
VCPH9L18_06415 H9L18_06420
VHYG7082_14515 G7082_14520
CSQCSCA_0123 CSCA_0124
CACECACET_c17510(oraS) CACET_c17520(oraE)
CEUA7L45_16575 A7L45_16580
CFMBJL90_14530 BJL90_14535
CARGRSJ17_08690 RSJ17_08695
CDRKB9W14_17920 B9W14_17925
AMTAmet_2370 Amet_2371
AOEClos_1695 Clos_1696
GFEGferi_26745 Gferi_26750
CALEFDN13_03000 FDN13_03005
CRSFQB35_06700 FQB35_06705
CPRFK7H06_08985 K7H06_08990
FPLAA4U99_15110 A4U99_15115
CDFCD630_04450(oraS) CD630_04460(oraE)
PDCCDIF630_00573(oraS) CDIF630_00574(oraE)
CDCCD196_0402(oraS) CD196_0403(oraE)
CDLCDR20291_0388(oraS) CDR20291_0389(oraE)
PDFCD630DERM_04450(oraS) CD630DERM_04460(oraE)
CSTCLOST_1290(oraE) CLOST_1291(oraS)
TEMJW646_03930 JW646_03935
TEBT8CH_0876(oraS) T8CH_0877(oraE)
DAIDesaci_1876 Desaci_1877
AACXDEACI_0849 DEACI_0850
VGUHYG85_19065 HYG85_19070
VPYHZI73_17660 HZI73_17665
ACAEHYG86_08055 HYG86_08060
AMIJEQM06_12580 EQM06_12585
AMICAmi3637_07705 Ami3637_07710
ABUTAmi103574_00575 Ami103574_00580
ETMCE91St48_39700(oraE) CE91St48_39710(oraS)
EUUADJ67_00780 ADJ67_00785
TTETTE1237 TTE1238(Sbm3)
TEXTeth514_1480 Teth514_1481
THXThet_1422 Thet_1423
TPDTeth39_1043 Teth39_1044
TBOThebr_1070 Thebr_1071
TWIThewi_1187 Thewi_1188
TOCToce_1485 Toce_1486
NTHNther_1169 Nther_1170
NCDACONDI_00603(oraS) ACONDI_00604(oraE)
HORHore_21070 Hore_21080
AFTBBF96_13580 BBF96_13585
KMEH0A61_00507(oraE) H0A61_00508(oraS)
SPOAEQM13_10945 EQM13_10950
KPARJL105_07120 JL105_07125
CAZOG3A45_03825 G3A45_03830
SEDZJYG23_00925 JYG23_00930
PFTJBW_01655 JBW_01656
MANRMPAN_008590(oraS) MPAN_008600(oraE)
MBJKQ51_00243(oraE) KQ51_00244(oraS)
TBMBK010_05540 BK010_05545
TBZBK011_05580 BK011_05585
TBKHF295_00030 HF295_00035
ARSADJ73_08375 ADJ73_08380
PACPPA2279 PPA2280
PAKHMPREF0675_5356 HMPREF0675_5357
PAVTIA2EST22_11175 TIA2EST22_11180
PAXTIA2EST36_11150 TIA2EST36_11155
PAZTIA2EST2_11095 TIA2EST2_11100
PAWPAZ_c23770 PAZ_c23780
PADTIIST44_04215 TIIST44_04220
PCNTIB1ST10_11615 TIB1ST10_11620
PACCPAC1_11625 PAC1_11630
PACHPAGK_2188
PACNTIA1EST1_11245 TIA1EST1_11250
CACNRN83_00025 RN83_00030
PRAPALO_10895
PRLBCB70_06940 BCB70_06945
CGRN4412665_00380 4412665_00381
PAUSNCTC13651_02408 NCTC13651_02409
PPCHMPREF9154_0895 HMPREF9154_0896
ARUBJ5A65_10515 J5A65_10520
ABATCFX1CAM_0748(oraS) CFX1CAM_0749(oraE)
TPITREPR_1360 TREPR_1361
SLRL21SP2_1021 L21SP2_1022
FHWRN87_08660 RN87_08665
FPDCTM68_09140 CTM68_09145
FCII6I83_05745 I6I83_05750
RHOZGXP67_19605
TMETmel_0908 Tmel_0909
TAFTHA_1163 THA_1164
THPBG95_05280 BG95_05285
THERY592_05360 Y592_05365
TFEJYK00_04215 JYK00_04220
FNOFnod_1642 Fnod_1643
FPEFerpe_1993 Ferpe_1994
FIANA23_09990 NA23_09995(oraE)
OCYOSSY52_03930(oraS) OSSY52_03940(oraE)
PMOPmob_1169 Pmob_1170
MPZMarpi_1536 Marpi_1537
MARNLN42_08185 LN42_08190
DTNDTL3_0762 DTL3_0763(oraE)
KOLKole_0359 Kole_0360
KPFIX53_10205 IX53_10210
MPGTheba_1254 Theba_1255
MINFMESINF_2280(oraE) MESINF_2281(oraS)
ASACATHSA_0993 ATHSA_0994
 » show all
Reference
1  [PMID:4711468]
  Authors
Somack R, Costilow RN.
  Title
Purification and properties of a pyridoxal phosphate and coenzyme B 12  dependent D- -ornithine 5,4-aminomutase.
  Journal
Biochemistry 12:2597-604 (1973)
DOI:10.1021/bi00738a008
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.3.5
IUBMB Enzyme Nomenclature: 5.4.3.5
ExPASy - ENZYME nomenclature database: 5.4.3.5
BRENDA, the Enzyme Database: 5.4.3.5
CAS: 62213-30-3
LinkDB

KEGG   REACTION: R02461
Entry
R02461                      Reaction                               
Name
D-ornithine 4,5-aminomutase
Definition
D-Ornithine <=> (2R,4S)-2,4-Diaminopentanoate
Equation
Reaction class
RC00719  C00515_C03943
Enzyme
Pathway
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
Orthology
K17898  D-ornithine 4,5-aminomutase subunit beta [EC:5.4.3.5]
K17899  D-ornithine 4,5-aminomutase subunit alpha [EC:5.4.3.5]
Other DBs
RHEA: 14896
LinkDB

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