KEGG ORTHOLOGY: K18054

ORTHOLOGY: K18054

Entry

K18054                      KO

Symbol

IDS3_2

Name

2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase [EC:1.14.11.24 1.14.11.25]

Pathway

map00999

Biosynthesis of various plant secondary metabolites

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00953

Mugineic acid biosynthesis, methionine => 3-epihydroxymugineic acid

Reaction

R07185

2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase(2-hydroxylating)

R07186

mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)

R07187

2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)

R12826

3-epihydroxy-2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various plant secondary metabolites
    K18054  IDS3_2; 2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.24  2'-deoxymugineic-acid 2'-dioxygenase
     K18054  IDS3_2; 2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase
    1.14.11.25  mugineic-acid 3-dioxygenase
     K18054  IDS3_2; 2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase

Other DBs

GO:	0033760 0033761

Genes

OSA:	130369635 4342505(GA20OX3)

OBR:

102718661

OGL:

127780041

BDI:	100823703 100834289

ATS:	109735390 109735399 109749040 109749041 109751383 109765035

TDC:	119300680 119314274 119315499 119325615 119325955 119328429 119331558 119332878 119340117 119367947

TUA:	125514132 125514172 125515769 125516388 125520118 125521867 125528513 125528766 125529970 125548929

LPER:

127299933 127299938 127308855 127308856 127308858 127308864 127310671 127318031 127323414 127323422

SBI:	8060703 8064596

ZMA:	100191339 100282204 103632609

MFLO:

136502552 136504605 136504782 136505587 136506164 136509198 136544785 136545263 136548059

SITA:

101755866 101760942 101776184 101782246 101783070

SVS:	117843314 117847021 117847643 117850051 117850415 117859550

PVIR:

120663816 120663818 120665194 120665196 120679320 120697011 120701041 120711749

PHAI:

112880075 112885977 112886617 112887730 112897064

AG:	BAA03647(IDS2) BAA75493(IDS3)

» show all

Reference

PMID:11117263

Authors

Nakanishi H, Yamaguchi H, Sasakuma T, Nishizawa NK, Mori S

Title

Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores.

Journal

Plant Mol Biol 44:199-207 (2000)
DOI:10.1023/A:1006491521586

Sequence

[ag:BAA75493 BAA03647]

LinkDB

ENZYME: 1.14.11.25

Entry

EC 1.14.11.25               Enzyme

Name

mugineic-acid 3-dioxygenase;
IDS2

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

Sysname

mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)

Reaction(IUBMB)

(1) mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2 [RN:R07186];
(2) 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2 [RN:R07187]

Reaction(KEGG)

R07186 R07187

Substrate

mugineic acid [CPD:C15500];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007];
2'-deoxymugineic acid [CPD:C15485]

Product

3-epihydroxymugineic acid [CPD:C15501];
succinate [CPD:C00042];
CO2 [CPD:C00011];
3-epihydroxy-2'-deoxymugineic acid [CPD:C15502]

Comment

Requires iron(II).

History

EC 1.14.11.25 created 2005

Pathway

ec00999

Biosynthesis of various plant secondary metabolites

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K18054

2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase

Genes

OSA:	130369635 4342505(GA20OX3)

OBR:

102718661

OGL:

127780041

BDI:	100823703 100834289

ATS:	109735390 109735399 109749040 109749041 109751383 109765035

TDC:	119300680 119314274 119315499 119325615 119325955 119328429 119331558 119332878 119340117 119367947

TAES:

123058911 123059088 123063285 123066068 123071846 123075122 123075123 123075205 123075325 123085810 123129321 123130050 123130056 123133271 123133287 123133288 123133290 123133291 123133299 123140642 123140785 123140815 123143122 123151949 123152262 123152821 123167844

TUA:	125514132 125514172 125515769 125516388 125520118 125521867 125528513 125528766 125529970 125548929

LPER:

127299933 127299938 127308855 127308856 127308858 127308864 127310671 127318031 127323414 127323422

LRD:	124653144 124656367 124658395 124658448 124662318 124662319 124680792 124686150 124686151 124686152 124686153 124686248 124686249 124686250 124686251 124689410 124689411 124689523 124691491 124691584 124706051

SBI:	8060703 8064596

ZMA:	100191339 100282204 103632609

MFLO:

136502552 136504605 136504782 136505587 136506164 136509198 136544785 136545263 136548059

SITA:

101755866 101760942 101776184 101782246 101783070

SVS:	117843314 117847021 117847643 117850051 117850415 117859550

PVIR:

120663816 120663818 120665194 120665196 120679320 120697011 120701041 120711749

PHAI:

112880075 112885977 112886617 112887730 112897064

» show all

Reference

1 [PMID:11117263]

Authors

Nakanishi H, Yamaguchi H, Sasakuma T, Nishizawa NK, Mori S

Title

Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores.

Journal

Plant Mol Biol 44:199-207 (2000)
DOI:10.1023/A:1006491521586

Sequence

[ag:BAA03647]

Reference

2 [PMID:8061321]

Authors

Okumura N, Nishizawa NK, Umehara Y, Ohata T, Nakanishi H, Yamaguchi T, Chino M, Mori S

Title

A dioxygenase gene (Ids2) expressed under iron deficiency conditions in the roots of Hordeum vulgare.

Journal

Plant Mol Biol 25:705-19 (1994)
DOI:10.1007/BF00029608

Sequence

[ag:BAA03647]

Other DBs

ExplorEnz - The Enzyme Database:

1.14.11.25

IUBMB Enzyme Nomenclature:

1.14.11.25

ExPASy - ENZYME nomenclature database:

1.14.11.25

BRENDA, the Enzyme Database:

1.14.11.25

LinkDB

REACTION: R07186

Entry

R07186                      Reaction

Name

mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)

Definition

Mugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2

Equation

C15500 + C00026 + C00007 <=> C15501 + C00042 + C00011

Reaction class

RC00661

C15500_C15501

Enzyme

1.14.11.25

Pathway

rn00999

Biosynthesis of various plant secondary metabolites

rn01100

Metabolic pathways

rn01110

Biosynthesis of secondary metabolites

Module

M00953

Mugineic acid biosynthesis, methionine => 3-epihydroxymugineic acid

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.25
     R07186  Mugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2

Orthology

K18054

2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase [EC:1.14.11.24 1.14.11.25]

Other DBs

RHEA:

14512

LinkDB

DBGET integrated database retrieval system