KEGG   ORTHOLOGY: K18256
Entry
K18256                      KO                                     
Symbol
phtC
Name
3,4-dihydroxyphthalate decarboxylase [EC:4.1.1.69]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K18256  phtC; 3,4-dihydroxyphthalate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.69  3,4-dihydroxyphthalate decarboxylase
     K18256  phtC; 3,4-dihydroxyphthalate decarboxylase
Other DBs
RN: R01634
GO: 0047556
Genes
MMC: Mmcs_1684
MKM: Mkms_1713
MJL: Mjls_1657
MGAU: MGALJ_00520
MPAE: K0O64_27345
MVA: Mvan_0543
MGI: Mflv_0540 Mflv_0622
MSP: Mspyr1_02030
MRH: MycrhN_3200
RKO: JWS14_17140
NCX: Nocox_41330(mtnB)
 » show all
Reference
  Authors
Stingley RL, Khan AA, Cerniglia CE.
  Title
Molecular characterization of a phenanthrene degradation pathway in Mycobacterium vanbaalenii PYR-1.
  Journal
Biochem Biophys Res Commun 322:133-46 (2004)
DOI:10.1016/j.bbrc.2004.07.089
Reference
  Authors
Pagnout C, Frache G, Poupin P, Maunit B, Muller JF, Ferard JF.
  Title
Isolation and characterization of a gene cluster involved in PAH degradation in Mycobacterium sp. strain SNP11: expression in Mycobacterium smegmatis mc(2)155.
  Journal
Res Microbiol 158:175-86 (2007)
DOI:10.1016/j.resmic.2006.11.002
  Sequence
[mva:Mvan_0543]
LinkDB

KEGG   ENZYME: 4.1.1.69
Entry
EC 4.1.1.69                 Enzyme                                 
Name
3,4-dihydroxyphthalate decarboxylase;
3,4-dihydroxyphthalate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Reaction(IUBMB)
3,4-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2 [RN:R01634]
Reaction(KEGG)
R01634
Substrate
3,4-dihydroxyphthalate [CPD:C03223]
Product
3,4-dihydroxybenzoate [CPD:C00230];
CO2 [CPD:C00011]
History
EC 4.1.1.69 created 1986
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18256  3,4-dihydroxyphthalate decarboxylase
Genes
MMCMmcs_1684
MKMMkms_1713
MJLMjls_1657
MGAUMGALJ_00520
MPAEK0O64_27345
MVAMvan_0543
MGIMflv_0540 Mflv_0622
MSPMspyr1_02030
MRHMycrhN_3200
RKOJWS14_17140
RGOKYT97_04300
GJIH1R19_01005
SSOII1A49_42795
NCXNocox_41330(mtnB)
AACDLWP59_07655 LWP59_26420 LWP59_34960 LWP59_37935
PSUUPsuf_076060
RMARGBA65_17435
 » show all
Reference
1  [PMID:7085570]
  Authors
Eaton RW, Ribbons DW.
  Title
Metabolism of dibutylphthalate and phthalate by Micrococcus sp. strain 12B.
  Journal
J Bacteriol 151:48-57 (1982)
DOI:10.1128/JB.151.1.48-57.1982
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.69
IUBMB Enzyme Nomenclature: 4.1.1.69
ExPASy - ENZYME nomenclature database: 4.1.1.69
BRENDA, the Enzyme Database: 4.1.1.69
CAS: 83137-76-2
LinkDB

KEGG   REACTION: R01634
Entry
R01634                      Reaction                               
Name
3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Definition
3,4-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2
Equation
Reaction class
RC00569  C00230_C03223
Enzyme
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00636  Phthalate degradation, phthalate => protocatechuate
Orthology
K18256  3,4-dihydroxyphthalate decarboxylase [EC:4.1.1.69]
Other DBs
RHEA: 18604
LinkDB

DBGET integrated database retrieval system