KEGG   ORTHOLOGY: K18310
Entry
K18310                      KO                                     
Symbol
RIMKLB, NAAGS-I
Name
beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41]
Pathway
map00250  Alanine, aspartate and glutamate metabolism
map01100  Metabolic pathways
Reaction
R10677  citrate:L-glutamate ligase (ADP-forming)
R10678  N-acetyl-L-aspartate:L-glutamate ligase (ADP, N-acetyl-L-aspartyl-L-glutamate-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K18310  RIMKLB, NAAGS-I; beta-citrylglutamate/N-acetylaspartylglutamate synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.1  Acid-D-ammonia (or amine) ligases (amide synthases)
    6.3.1.17  beta-citrylglutamate synthase
     K18310  RIMKLB, NAAGS-I; beta-citrylglutamate/N-acetylaspartylglutamate synthase
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.41  N-acetylaspartylglutamate synthase
     K18310  RIMKLB, NAAGS-I; beta-citrylglutamate/N-acetylaspartylglutamate synthase
Genes
HSA: 57494(RIMKLB)
PTR: 735860(RIMKLB)
PPS: 100974820(RIMKLB)
GGO: 101136567(RIMKLB) 129529357
PON: 100441104(RIMKLB)
PPYG: 129009422(RIMKLB)
NLE: 100593570(RIMKLB)
HMH: 116456202 116472644(RIMKLB) 116481450
SSYN: 129482966 129483406(RIMKLB) 129490478
MCC: 722261(RIMKLB)
MCF: 102124154(RIMKLB) 102128847
MTHB: 126931378 126935689 126940883
MNI: 105499881(RIMKLB)
CSAB: 103218536(RIMKLB)
CATY: 105587959(RIMKLB)
PANU: 101024010(RIMKLB)
TGE: 112635206(RIMKLB)
MLEU: 105552618(RIMKLB)
RRO: 104672842(RIMKLB)
RBB: 108543684(RIMKLB)
TFN: 117090541(RIMKLB)
PTEH: 111526616(RIMKLB)
CANG: 105519900(RIMKLB)
CJC: 100406491(RIMKLB)
SBQ: 101033047(RIMKLB)
CIMI: 108291858(RIMKLB) 108311366
ANAN: 105721347(RIMKLB)
CSYR: 103251714(RIMKLB)
MMUR: 105878274(RIMKLB)
LCAT: 123640042(RIMKLB)
ERUF: 138396887(RIMKLB)
PCOQ: 105805100(RIMKLB)
OGA: 100941690(RIMKLB)
MMU: 108653(Rimklb)
MCAL: 110296264(Rimklb)
MPAH: 110316335(Rimklb)
RNO: 100362344(Rimklbl1) 362428(Rimklb)
MCOC: 116099539(Rimklb)
ANU: 117715398(Rimklb)
ASYL: 127677622(Rimklb)
MUN: 110556298(Rimklb)
CGE: 100760031(Rimklb)
MAUA: 101842752(Rimklb)
PROB: 127236141(Rimklb)
PLEU: 114683483(Rimklb)
PMAV: 102917511(Rimklb)
MORG: 121438947(Rimklb)
MFOT: 126514898
AAMP: 119808422(Rimklb)
CNL: 130876625(Rimklb)
NGI: 103727467(Rimklb)
HGL: 101706744(Rimklb)
CPOC: 100732576(Rimklb)
CCAN: 109697724(Rimklb)
DORD: 105991108(Rimklb)
DSP: 122127019(Rimklb)
DMER: 138803654 138835348
PLOP: 125342895(Rimklb)
NCAR: 124983424
MMMA: 107159921(Rimklb)
ITI: 101958646(Rimklb)
OCU: 100346793
OPI: 101523234(RIMKLB)
OCZ: 121155592(RIMKLB)
TUP: 102472940(RIMKLB)
GVR: 103597920(RIMKLB)
CFA: 486698(RIMKLB)
CLUD: 112675320(RIMKLB)
VVP: 112917302(RIMKLB)
VLG: 121479857(RIMKLB)
NPO: 129517123(RIMKLB)
AML: 100473320(RIMKLB)
UMR: 103669163(RIMKLB)
UAH: 113257923(RIMKLB)
UAR: 123781552(RIMKLB)
ELK: 111142053
LLV: 125106794
MPUF: 101680352(RIMKLB)
MNP: 132019465(RIMKLB)
MLK: 131839093(RIMKLB)
NVS: 122891599(RIMKLB)
ORO: 101374535(RIMKLB)
EJU: 114221687(RIMKLB)
ZCA: 113921819(RIMKLB)
MLX: 118025692(RIMKLB)
MANO: 123843990(RIMKLB)
NSU: 110580730(RIMKLB)
LWW: 102741413(RIMKLB)
FCA: 101097740(RIMKLB)
PYU: 121022064(RIMKLB)
PCOO: 112867654(RIMKLB)
PBG: 122473789(RIMKLB)
PVIV: 125170874(RIMKLB)
LRUF: 124502657
LGF: 123589928(RIMKLB)
AJU: 106965320
PTG: 102963865(RIMKLB)
PPAD: 109276058(RIMKLB)
PUC: 125920076
PLEZ: 122224207(RIMKLB)
HHV: 120222721(RIMKLB)
CCRU: 144227448(RIMKLB)
BTA: 538579(RIMKLB)
BOM: 102269649(RIMKLB)
BIU: 109559695(RIMKLB)
BJV: 133248166(RIMKLB)
BBUB: 102397788(RIMKLB) 112578013
BKE: 129644398(RIMKLB)
BBIS: 104995473(RIMKLB)
CHX: 102176861(RIMKLB)
OAS: 101102554(RIMKLB)
BTAX: 128047549(RIMKLB)
CSUM: 138079110(RIMKLB)
ODA: 120858791(RIMKLB)
CCAD: 122423372(RIMKLB) 122439954
MREE: 136172393(RIMKLB)
OVR: 110141999(RIMKLB)
MBEZ: 129535835(RIMKLB)
SSC: 100152915(RIMKLB)
CFR: 102503881(RIMKLB)
CBAI: 105062179(RIMKLB)
CDK: 105098170(RIMKLB)
VPC: 102526778(RIMKLB)
BACU: 103019013(RIMKLB)
BMUS: 118884598 118887952 118902028(RIMKLB)
LVE: 103069710(RIMKLB)
OOR: 101273054(RIMKLB)
LALB: 132529886(RIMKLB)
GMF: 115840986(RIMKLB)
DDP: 132433486(RIMKLB)
DLE: 111176728(RIMKLB)
PCAD: 102975069 102981532(RIMKLB)
PSIU: 116746837 116760947(RIMKLB)
PPHC: 136131020(RIMKLB) 136141863
NASI: 112391802(RIMKLB)
ECB: 100061350(RIMKLB)
EPZ: 103564581(RIMKLB)
EAI: 106837431(RIMKLB)
MYB: 102245342(RIMKLB)
MYD: 102752373(RIMKLB)
MMYO: 118650363(RIMKLB)
MLF: 102441683(RIMKLB)
MDT: 132227250(RIMKLB)
MYUM: 139007363(RIMKLB)
PKL: 118728963(RIMKLB)
EFUS: 103285400(RIMKLB)
MNA: 107544073(RIMKLB)
DRO: 112322046(RIMKLB)
SHON: 119002540(RIMKLB)
AJM: 119065675(RIMKLB)
PDIC: 114514072(RIMKLB)
PHAS: 123819342(RIMKLB)
MMF: 118624708(RIMKLB)
PPAM: 129085032(RIMKLB)
HAI: 109372752(RIMKLB)
RFQ: 117028564(RIMKLB)
PALE: 102880426(RIMKLB)
PGIG: 120611695(RIMKLB)
PVP: 105295916(RIMKLB)
RAY: 107501656(RIMKLB)
MJV: 108396116(RIMKLB)
TOD: 119247737(RIMKLB)
SARA: 101554225(RIMKLB)
SFUM: 130042509(RIMKLB)
SETR: 126006581(RIMKLB)
LAV: 100657534(RIMKLB)
TMU: 101361972
ETF: 101645920(RIMKLB)
DNM: 101416522(RIMKLB)
MDO: 100013787(RIMKLB)
GAS: 123250757(RIMKLB)
SHR: 100930894(RIMKLB)
AFZ: 127539203
PCW: 110213807(RIMKLB)
TVP: 118850782(RIMKLB)
PBRV: 138175639(RIMKLB)
MLAO: 141493276(RIMKLB)
OAA: 100090307(RIMKLB)
TACU: 119946517(RIMKLB)
GGA: 418255(RIMKLB)
PCOC: 116240958(RIMKLB)
MGP: 104916636
CJO: 107318392(RIMKLB)
TPAI: 128089909(RIMKLB)
LMUT: 125687916(RIMKLB)
NMEL: 110397764(RIMKLB)
APLA: 101792875(RIMKLB)
AACU: 137865777(RIMKLB)
OJA: 118158348(RIMKLB)
ACYG: 106048091(RIMKLB)
CATA: 118247607(RIMKLB)
AFUL: 116490791(RIMKLB)
TGU: 100220208(RIMKLB)
LSR: 110472321(RIMKLB)
VMC: 128803236(RIMKLB)
VCHA: 128783570(RIMKLB)
AIB: 137469226(RIMKLB)
SCAN: 103827201(RIMKLB)
PMOA: 120497743(RIMKLB)
OTC: 121341027(RIMKLB)
PRUF: 121349851(RIMKLB)
ATRC: 139592772(RIMKLB)
MATE: 118690716(RIMKLB)
MAEN: 136571684(RIMKLB)
GFR: 102035986(RIMKLB)
FAB: 101814507(RIMKLB)
OMA: 130255587(RIMKLB)
PHI: 102111957(RIMKLB)
PMAJ: 107210434(RIMKLB)
CCAE: 111925810(RIMKLB)
CCW: 104690266(RIMKLB)
CBRC: 103616673(RIMKLB)
ACOE: 138111478(RIMKLB)
ETL: 114069342(RIMKLB)
ZAB: 102064947(RIMKLB)
ZLE: 135451535(RIMKLB)
ACHL: 103811885(RIMKLB)
SVG: 106859828(RIMKLB)
MMEA: 130579182(RIMKLB)
HRT: 120748584(RIMKLB)
SATI: 136375597(RIMKLB)
CFAI: 136284979(RIMKLB)
CCIC: 134056867(RIMKLB)
FPG: 101913481(RIMKLB)
FCH: 102056126(RIMKLB)
FRS: 119149073(RIMKLB)
CCRI: 104158756(RIMKLB)
NNT: 104411662(RIMKLB)
SHAB: 115605282(RIMKLB)
POCC: 134161359(RIMKLB)
ACUN: 113491069(RIMKLB)
ANOC: 141958887(RIMKLB)
SURA: 141944798(RIMKLB)
TALA: 104365181(RIMKLB)
ACHC: 115352600(RIMKLB)
HALD: 104321852(RIMKLB)
HLE: 104836674(RIMKLB)
AGEN: 126047837
HHAR: 128143163(RIMKLB)
BBUT: 142042080(RIMKLB)
GCL: 127017595
CSTI: 104557469(RIMKLB)
LDI: 104343382(RIMKLB)
MNB: 103775226(RIMKLB)
DPUB: 104306895(RIMKLB)
PPUS: 135175369(RIMKLB)
IIN: 128972660(RIMKLB)
AVIT: 104268972(RIMKLB)
BRHI: 104488456
EGZ: 104122771(RIMKLB)
NNI: 104014577(RIMKLB)
PCRI: 104036849(RIMKLA)
PCAO: 104053397(RIMKLB)
PARX: 142064924(RIMKLB)
PADL: 103915115(RIMKLB)
AFOR: 103899962(RIMKLB)
FGA: 104072777(RIMKLB)
CBOR: 142088278(RIMKLB)
GSTE: 104257247(RIMKLB)
CBOY: 140659032(RIMKLB)
MAME: 142413336(RIMKLB)
CLV: 102098362(RIMKLB)
CNIC: 135994851(RIMKLB)
MUI: 104538317(RIMKLB)
PGUU: 104458927(RIMKLB)
PLET: 104626869(RIMKLB)
EHS: 104510567(RIMKLB)
CMAC: 104474785(RIMKLB)
CUCA: 104060632(RIMKLB)
PCUR: 138724594(RIMKLB)
TEO: 104382280
BREG: 104641295(RIMKLB)
GAME: 129208679(RIMKLB)
OHA: 104332450(RIMKLB)
ACAR: 104532919(RIMKLB)
CPEA: 104394530(RIMKLB)
CVF: 104294502(RIMKLB)
RTD: 128902766(RIMKLB)
CRID: 134525618(RIMKLB)
LMIC: 141743796(RIMKLB)
NARQ: 141469139(RIMKLB)
AAM: 106495722(RIMKLB)
AROW: 112973974(RIMKLB)
NPD: 112952039(RIMKLB)
TGT: 104580212(RIMKLB)
DNE: 112992432(RIMKLB)
SCAM: 104152046(RIMKLB)
ASN: 102373845(RIMKLB)
AMJ: 102576775(RIMKLB)
CPOO: 109316234(RIMKLB)
GGN: 109296594(RIMKLB)
PSS: 102451018(RIMKLB)
CIZ: 142017495(RIMKLB)
CMY: 102933090(RIMKLB)
CCAY: 125623379(RIMKLB)
LKP: 140898971(RIMKLB)
NDS: 141974977(RIMKLB)
DCC: 119859155(RIMKLB)
CPIC: 101943668(RIMKLB)
TST: 117884982(RIMKLB)
EOB: 135895333(RIMKLB)
CABI: 116823843(RIMKLB)
MRV: 120404562(RIMKLB)
EMQ: 137141971(RIMKLB)
ACS: 100563778(rimklb)
ASAO: 132767973(RIMKLB)
PVT: 110069781(RIMKLB)
SUND: 121921715(RIMKLB)
PBI: 103055545(RIMKLB)
PMUR: 107288539(RIMKLB)
CTIG: 120318691(RIMKLB)
TSR: 106544566(RIMKLB)
PGUT: 117661914(RIMKLB)
PCAE: 139310985(RIMKLB)
APRI: 131189735(RIMKLB)
PTEX: 113444557(RIMKLB)
NSS: 113425290(RIMKLB)
VKO: 123017759(RIMKLB)
PMUA: 114588043(RIMKLB)
PRAF: 128405389(RIMKLB)
ZVI: 118097943(RIMKLB)
HCG: 128346831(RIMKLB)
GJA: 107117747(RIMKLB)
STOW: 125437091(RIMKLB)
EMC: 129345231(RIMKLB)
XLA: 108696039 108697330
XTR: 100486701(rimklb)
NPR: 108799485(RIMKLB)
RTEM: 120946910(RIMKLB)
ACAT: 141105844(RIMKLB)
PADS: 140339450(RIMKLB)
BBUF: 121005412(RIMKLB)
BGAR: 122941782(RIMKLB)
DTC: 141056266(RIMKLB)
HSQ: 130283165(RIMKLB)
PCOB: 135056857(RIMKLB)
PWL: 138303676(RIMKLB)
MUO: 115457690(RIMKLB)
GSH: 117350096(RIMKLB)
DRE: 447815(rimkla)
DAES: 130233465(rimkla)
SRX: 107711947 107717536
SANH: 107669631
SGH: 107556480 107591767
CCAR: 109084979 109084984
CAUA: 113078389 113093917 113107768
CGIB: 127964047 128018591
PTET: 122350397(rimkla)
LROH: 127170090(rimkla)
GRF: 141287159(rimkla)
OMC: 131545407(rimkla)
PPRM: 120483739(rimkla)
RKG: 130094558(rimkla)
MAMB: 125279787(rimkla)
CIDE: 127517732
CERY: 137027117(rimkla)
MASI: 127414466 127424193
TROS: 130567859(rimkla)
TDW: 130439951(rimkla)
MANU: 129413961(rimkla)
PDAB: 135729453(rimkla)
IPU: 108265850
IFU: 128607997(rimkla)
PHYP: 113529230
SMEO: 124399561(rimkla)
TFD: 113655760(rimkla)
TVC: 132853464(rimkla)
CGAR: 128530413(rimkla)
NGRA: 132893232(rimkla)
TRN: 134318214(rimkla)
AMEX: 103035057(rimkla)
CMAO: 118813696(rimkla)
EEE: 113572086
CHAR: 105902183(rimkla)
SPIL: 134087340(rimkla)
ASAD: 121712880(rimkla)
TRU: 101062827
TFS: 130530628(rimkla)
TNG: GSTEN00013753G001
LCO: 104920219
NCC: 104955181(rimkla)
TBEN: 117494141(rimkla)
CGOB: 115011073
PGEO: 117449663(rimkla)
GACU: 117541819(rimkla)
EMAC: 134870674(rimkla)
ELY: 117258509(rimkla)
EFO: 125891718(rimkla)
PLEP: 121947276(rimkla)
SLUC: 116040663(rimkla)
SVIT: 144520736(rimkla)
ECRA: 117948232(rimkla)
ESP: 116692402
PFLV: 114558866
PFLT: 120558683(rimkla)
GAT: 120828693(rimkla)
PPUG: 119222662(rimkla)
AFB: 129100051(rimkla)
CLUM: 117732964(rimkla)
PSWI: 130199585(rimkla)
CANA: 137800381(rimkla)
CVE: 137889322(rimkla)
AMIR: 142948848(rimkla)
MSAM: 119905637(rimkla)
SCHU: 122882832(rimkla)
EARM: 139289516(rimkla)
CUD: 121518035(rimkla)
SPUL: 138590367(rimkla)
LMIX: 132989383(rimkla)
HTC: 141799542(rimkla)
ALAT: 119022909(rimkla)
ASTR: 137611234(rimkla)
PKLU: 139210026(rimkla)
MZE: 101477475(rimkla)
ONL: 100698845
OAU: 116309725(rimkla)
OLA: 101169452(rimklb)
OML: 112159079(rimkla)
CSAI: 133457317(rimkla)
XMA: 102218635
XCO: 114141086
XHE: 116725681
PRET: 103467997(rimkla)
PFOR: 103138952(rimkla)
PLAI: 106957454(rimkla)
PMEI: 106907435(rimkla)
GAF: 122836233(rimkla)
PPRL: 129372418(rimkla)
CVG: 107088869(rimkla)
CTUL: 119797064(rimkla)
GMU: 124867677(rimkla)
NFU: 107390714
KMR: 108236831(rimkla)
ALIM: 106524174
NWH: 119417065(rimkla)
LTU: 140272080(rimkla)
AOCE: 111585273(rimkla)
EJA: 138192771(rimkla)
BFRE: 138615433(rimkla)
MCEP: 124997852(rimkla)
CSEM: 103384935
POV: 109630621(rimkla)
SSEN: 122776960(rimkla)
SSOE: 131468340(rimkla)
HHIP: 117764653(rimkla)
HSP: 118110963(rimkla)
PPLT: 128442387(rimkla)
SMAU: 118317585(rimkla)
LCF: 108891717
SDU: 111219047
SLAL: 111670604
XGL: 120804092(rimkla)
HCQ: 109526583
SSCV: 125988093(rimkla)
SBIA: 133508604(rimkla)
PEE: 133405192(rimkla)
PTAO: 133482673(rimkla)
BPEC: 110161111
ENY: 140362622(rimkla)
MALB: 109970719
BSPL: 114858903(rimkla)
SJO: 128357364(rimkla)
SSCO: 133988051(rimkla)
TTY: 137184314(rimkla)
GMH: 115542815
SASA: 106567384 106572158
STRU: 115166047 115168921
OTW: 112215953 112221609
OMY: 110491822 110532211
OGO: 124017459 124031877
ONE: 115102623 115132092
OKI: 109869491 109907940
OKE: 118360188 118361096
OMM: 135504472 135528563
OCLA: 139368314 139416442
SALP: 111966388 111976646
SNH: 120059373 120060966
SFON: 129824174 129830218
CCLU: 121538272 121545958
ELS: 105013808
OEP: 134019365(rimkla)
SFM: 108918203 108924922
PKI: 111856970 111859075(rimkla)
AANG: 118208179(rimkla)
AROT: 135233914(rimkla)
CCOG: 133139031(rimkla)
LOC: 102687393(rimkla)
PSPA: 121296514 121325367 121328885 121329280
ARUT: 117424072 117425213 117425745 117432003
PSEX: 120530966(rimkla) 120535665
LCM: 102351441(RIMKLB) 102354509(RIMKLA)
CMK: 103190080(rimkla)
RTP: 109924989(rimkla)
CPLA: 122540248(rimkla)
HOC: 132833521(rimkla)
LERI: 129711474(rimkla)
HAKA: 140718279(rimkla)
PMRN: 116937615 116948844
LRJ: 133345229
 » show all
Reference
PMID:20657015
  Authors
Collard F, Stroobant V, Lamosa P, Kapanda CN, Lambert DM, Muccioli GG, Poupaert JH, Opperdoes F, Van Schaftingen E
  Title
Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.
  Journal
J Biol Chem 285:29826-33 (2010)
DOI:10.1074/jbc.M110.152629
  Sequence
[mmu:108653]
LinkDB

KEGG   ENZYME: 6.3.1.17
Entry
EC 6.3.1.17                 Enzyme                                 
Name
beta-citrylglutamate synthase;
NAAG synthetase I;
NAAGS-I;
RIMKLB (gene name) (ambiguous)
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
Sysname
citrate:L-glutamate ligase (ADP-forming)
Reaction(IUBMB)
ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate [RN:R10677]
Reaction(KEGG)
R10677
Substrate
ATP [CPD:C00002];
citrate [CPD:C00158];
L-glutamate [CPD:C00025]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
beta-citryl-L-glutamate [CPD:C20775]
Comment
The enzyme, found in animals, also has the activity of EC 6.3.2.41, N-acetylaspartylglutamate synthase.
History
EC 6.3.1.17 created 2014
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
ec01100  Metabolic pathways
Orthology
K18310  beta-citrylglutamate/N-acetylaspartylglutamate synthase
Genes
HSA: 57494(RIMKLB)
PTR: 735860(RIMKLB)
PPS: 100974820(RIMKLB)
GGO: 101136567(RIMKLB) 129529357
PON: 100441104(RIMKLB)
PPYG: 129009422(RIMKLB)
NLE: 100593570(RIMKLB)
HMH: 116456202 116472644(RIMKLB) 116481450
SSYN: 129482966 129483406(RIMKLB) 129490478
MCC: 722261(RIMKLB)
MCF: 102124154(RIMKLB) 102128847
MTHB: 126931378 126935689 126940883
MNI: 105499881(RIMKLB)
CSAB: 103218536(RIMKLB)
CATY: 105587959(RIMKLB)
PANU: 101024010(RIMKLB)
TGE: 112635206(RIMKLB)
MLEU: 105552618(RIMKLB)
RRO: 104672842(RIMKLB)
RBB: 108543684(RIMKLB)
TFN: 117090541(RIMKLB)
PTEH: 111526616(RIMKLB)
CANG: 105519900(RIMKLB)
CJC: 100406491(RIMKLB)
SBQ: 101033047(RIMKLB)
CIMI: 108291858(RIMKLB) 108311366
ANAN: 105721347(RIMKLB)
CSYR: 103251714(RIMKLB)
MMUR: 105878274(RIMKLB)
LCAT: 123640042(RIMKLB)
ERUF: 138396887(RIMKLB)
PCOQ: 105805100(RIMKLB)
OGA: 100941690(RIMKLB)
MMU: 108653(Rimklb)
MCAL: 110296264(Rimklb)
MPAH: 110316335(Rimklb)
RNO: 100362344(Rimklbl1) 362428(Rimklb)
MCOC: 116099539(Rimklb)
ANU: 117715398(Rimklb)
ASYL: 127677622(Rimklb)
MUN: 110556298(Rimklb)
CGE: 100760031(Rimklb)
MAUA: 101842752(Rimklb)
PROB: 127236141(Rimklb)
PLEU: 114683483(Rimklb)
PMAV: 102917511(Rimklb)
MORG: 121438947(Rimklb)
MFOT: 126514898
AAMP: 119808422(Rimklb)
CNL: 130876625(Rimklb)
NGI: 103727467(Rimklb)
HGL: 101706744(Rimklb)
CPOC: 100732576(Rimklb)
CCAN: 109697724(Rimklb)
DORD: 105991108(Rimklb)
DSP: 122127019(Rimklb)
DMER: 138803654 138835348
PLOP: 125342895(Rimklb)
NCAR: 124983424
MMMA: 107159921(Rimklb)
ITI: 101958646(Rimklb)
OCU: 100346793
OPI: 101523234(RIMKLB)
OCZ: 121155592(RIMKLB)
TUP: 102472940(RIMKLB)
GVR: 103597920(RIMKLB)
CFA: 486698(RIMKLB)
CLUD: 112675320(RIMKLB)
VVP: 112917302(RIMKLB)
VLG: 121479857(RIMKLB)
NPO: 129517123(RIMKLB)
AML: 100473320(RIMKLB)
UMR: 103669163(RIMKLB)
UAH: 113257923(RIMKLB)
UAR: 123781552(RIMKLB)
ELK: 111142053
LLV: 125106794
MPUF: 101680352(RIMKLB)
MNP: 132019465(RIMKLB)
MLK: 131839093(RIMKLB)
NVS: 122891599(RIMKLB)
ORO: 101374535(RIMKLB)
EJU: 114221687(RIMKLB)
ZCA: 113921819(RIMKLB)
MLX: 118025692(RIMKLB)
MANO: 123843990(RIMKLB)
NSU: 110580730(RIMKLB)
LWW: 102741413(RIMKLB)
FCA: 101097740(RIMKLB)
PYU: 121022064(RIMKLB)
PCOO: 112867654(RIMKLB)
PBG: 122473789(RIMKLB)
PVIV: 125170874(RIMKLB)
LRUF: 124502657
LGF: 123589928(RIMKLB)
AJU: 106965320
PTG: 102963865(RIMKLB)
PPAD: 109276058(RIMKLB)
PUC: 125920076
PLEZ: 122224207(RIMKLB)
HHV: 120222721(RIMKLB)
CCRU: 144227448(RIMKLB)
BTA: 538579(RIMKLB)
BOM: 102269649(RIMKLB)
BIU: 109559695(RIMKLB)
BJV: 133248166(RIMKLB)
BBUB: 102397788(RIMKLB) 112578013
BKE: 129644398(RIMKLB)
BBIS: 104995473(RIMKLB)
CHX: 102176861(RIMKLB)
OAS: 101102554(RIMKLB)
BTAX: 128047549(RIMKLB)
CSUM: 138079110(RIMKLB)
ODA: 120858791(RIMKLB)
CCAD: 122423372(RIMKLB) 122439954
MREE: 136172393(RIMKLB)
OVR: 110141999(RIMKLB)
MBEZ: 129535835(RIMKLB)
SSC: 100152915(RIMKLB)
CFR: 102503881(RIMKLB)
CBAI: 105062179(RIMKLB)
CDK: 105098170(RIMKLB)
VPC: 102526778(RIMKLB)
BACU: 103019013(RIMKLB)
BMUS: 118884598 118887952 118902028(RIMKLB)
LVE: 103069710(RIMKLB)
OOR: 101273054(RIMKLB)
LALB: 132529886(RIMKLB)
GMF: 115840986(RIMKLB)
DDP: 132433486(RIMKLB)
DLE: 111176728(RIMKLB)
PCAD: 102975069 102981532(RIMKLB)
PSIU: 116746837 116760947(RIMKLB)
PPHC: 136131020(RIMKLB) 136141863
NASI: 112391802(RIMKLB)
ECB: 100061350(RIMKLB)
EPZ: 103564581(RIMKLB)
EAI: 106837431(RIMKLB)
MYB: 102245342(RIMKLB)
MYD: 102752373(RIMKLB)
MMYO: 118650363(RIMKLB)
MLF: 102441683(RIMKLB)
MDT: 132227250(RIMKLB)
MYUM: 139007363(RIMKLB)
PKL: 118728963(RIMKLB)
EFUS: 103285400(RIMKLB)
MNA: 107544073(RIMKLB)
DRO: 112322046(RIMKLB)
SHON: 119002540(RIMKLB)
AJM: 119065675(RIMKLB)
PDIC: 114514072(RIMKLB)
PHAS: 123819342(RIMKLB)
MMF: 118624708(RIMKLB)
PPAM: 129085032(RIMKLB)
HAI: 109372752(RIMKLB)
RFQ: 117028564(RIMKLB)
PALE: 102880426(RIMKLB)
PGIG: 120611695(RIMKLB)
PVP: 105295916(RIMKLB)
RAY: 107501656(RIMKLB)
MJV: 108396116(RIMKLB)
TOD: 119247737(RIMKLB)
SARA: 101554225(RIMKLB)
SFUM: 130042509(RIMKLB)
SETR: 126006581(RIMKLB)
LAV: 100657534(RIMKLB)
TMU: 101361972
ETF: 101645920(RIMKLB)
DNM: 101416522(RIMKLB)
MDO: 100013787(RIMKLB)
GAS: 123250757(RIMKLB)
SHR: 100930894(RIMKLB)
AFZ: 127539203
PCW: 110213807(RIMKLB)
TVP: 118850782(RIMKLB)
PBRV: 138175639(RIMKLB)
MLAO: 141493276(RIMKLB)
OAA: 100090307(RIMKLB)
TACU: 119946517(RIMKLB)
GGA: 418255(RIMKLB)
PCOC: 116240958(RIMKLB)
MGP: 104916636
CJO: 107318392(RIMKLB)
TPAI: 128089909(RIMKLB)
LMUT: 125687916(RIMKLB)
NMEL: 110397764(RIMKLB)
APLA: 101792875(RIMKLB)
AACU: 137865777(RIMKLB)
OJA: 118158348(RIMKLB)
ACYG: 106048091(RIMKLB)
CATA: 118247607(RIMKLB)
AFUL: 116490791(RIMKLB)
TGU: 100220208(RIMKLB)
LSR: 110472321(RIMKLB)
VMC: 128803236(RIMKLB)
VCHA: 128783570(RIMKLB)
AIB: 137469226(RIMKLB)
SCAN: 103827201(RIMKLB)
PMOA: 120497743(RIMKLB)
OTC: 121341027(RIMKLB)
PRUF: 121349851(RIMKLB)
ATRC: 139592772(RIMKLB)
MATE: 118690716(RIMKLB)
MAEN: 136571684(RIMKLB)
GFR: 102035986(RIMKLB)
FAB: 101814507(RIMKLB)
OMA: 130255587(RIMKLB)
PHI: 102111957(RIMKLB)
PMAJ: 107210434(RIMKLB)
CCAE: 111925810(RIMKLB)
CCW: 104690266(RIMKLB)
CBRC: 103616673(RIMKLB)
ACOE: 138111478(RIMKLB)
ETL: 114069342(RIMKLB)
ZAB: 102064947(RIMKLB)
ZLE: 135451535(RIMKLB)
ACHL: 103811885(RIMKLB)
SVG: 106859828(RIMKLB)
MMEA: 130579182(RIMKLB)
HRT: 120748584(RIMKLB)
SATI: 136375597(RIMKLB)
CFAI: 136284979(RIMKLB)
CCIC: 134056867(RIMKLB)
FPG: 101913481(RIMKLB)
FCH: 102056126(RIMKLB)
FRS: 119149073(RIMKLB)
CCRI: 104158756(RIMKLB)
NNT: 104411662(RIMKLB)
SHAB: 115605282(RIMKLB)
POCC: 134161359(RIMKLB)
ACUN: 113491069(RIMKLB)
ANOC: 141958887(RIMKLB)
SURA: 141944798(RIMKLB)
TALA: 104365181(RIMKLB)
ACHC: 115352600(RIMKLB)
HALD: 104321852(RIMKLB)
HLE: 104836674(RIMKLB)
AGEN: 126047837
HHAR: 128143163(RIMKLB)
BBUT: 142042080(RIMKLB)
GCL: 127017595
CSTI: 104557469(RIMKLB)
LDI: 104343382(RIMKLB)
MNB: 103775226(RIMKLB)
DPUB: 104306895(RIMKLB)
PPUS: 135175369(RIMKLB)
IIN: 128972660(RIMKLB)
AVIT: 104268972(RIMKLB)
BRHI: 104488456
EGZ: 104122771(RIMKLB)
NNI: 104014577(RIMKLB)
PCRI: 104036849(RIMKLA)
PCAO: 104053397(RIMKLB)
PARX: 142064924(RIMKLB)
PADL: 103915115(RIMKLB)
AFOR: 103899962(RIMKLB)
FGA: 104072777(RIMKLB)
CBOR: 142088278(RIMKLB)
GSTE: 104257247(RIMKLB)
CBOY: 140659032(RIMKLB)
MAME: 142413336(RIMKLB)
CLV: 102098362(RIMKLB)
CNIC: 135994851(RIMKLB)
MUI: 104538317(RIMKLB)
PGUU: 104458927(RIMKLB)
PLET: 104626869(RIMKLB)
EHS: 104510567(RIMKLB)
CMAC: 104474785(RIMKLB)
CUCA: 104060632(RIMKLB)
PCUR: 138724594(RIMKLB)
TEO: 104382280
BREG: 104641295(RIMKLB)
GAME: 129208679(RIMKLB)
OHA: 104332450(RIMKLB)
ACAR: 104532919(RIMKLB)
CPEA: 104394530(RIMKLB)
CVF: 104294502(RIMKLB)
RTD: 128902766(RIMKLB)
CRID: 134525618(RIMKLB)
LMIC: 141743796(RIMKLB)
NARQ: 141469139(RIMKLB)
AAM: 106495722(RIMKLB)
AROW: 112973974(RIMKLB)
NPD: 112952039(RIMKLB)
TGT: 104580212(RIMKLB)
DNE: 112992432(RIMKLB)
SCAM: 104152046(RIMKLB)
ASN: 102373845(RIMKLB)
AMJ: 102576775(RIMKLB)
CPOO: 109316234(RIMKLB)
GGN: 109296594(RIMKLB)
PSS: 102451018(RIMKLB)
CIZ: 142017495(RIMKLB)
CMY: 102933090(RIMKLB)
CCAY: 125623379(RIMKLB)
LKP: 140898971(RIMKLB)
NDS: 141974977(RIMKLB)
DCC: 119859155(RIMKLB)
CPIC: 101943668(RIMKLB)
TST: 117884982(RIMKLB)
EOB: 135895333(RIMKLB)
CABI: 116823843(RIMKLB)
MRV: 120404562(RIMKLB)
EMQ: 137141971(RIMKLB)
ACS: 100563778(rimklb)
ASAO: 132767973(RIMKLB)
PVT: 110069781(RIMKLB)
SUND: 121921715(RIMKLB)
PBI: 103055545(RIMKLB)
PMUR: 107288539(RIMKLB)
CTIG: 120318691(RIMKLB)
TSR: 106544566(RIMKLB)
PGUT: 117661914(RIMKLB)
PCAE: 139310985(RIMKLB)
APRI: 131189735(RIMKLB)
PTEX: 113444557(RIMKLB)
NSS: 113425290(RIMKLB)
VKO: 123017759(RIMKLB)
PMUA: 114588043(RIMKLB)
PRAF: 128405389(RIMKLB)
ZVI: 118097943(RIMKLB)
HCG: 128346831(RIMKLB)
GJA: 107117747(RIMKLB)
STOW: 125437091(RIMKLB)
EMC: 129345231(RIMKLB)
XLA: 108696039 108697330
XTR: 100486701(rimklb)
NPR: 108799485(RIMKLB)
RTEM: 120946910(RIMKLB)
ACAT: 141105844(RIMKLB)
PADS: 140339450(RIMKLB)
BBUF: 121005412(RIMKLB)
BGAR: 122941782(RIMKLB)
DTC: 141056266(RIMKLB)
HSQ: 130283165(RIMKLB)
PCOB: 135056857(RIMKLB)
PWL: 138303676(RIMKLB)
MUO: 115457690(RIMKLB)
GSH: 117350096(RIMKLB)
DRE: 447815(rimkla)
DAES: 130233465(rimkla)
SRX: 107711947 107717536
SANH: 107669631
SGH: 107556480 107591767
CCAR: 109084979 109084984
CAUA: 113078389 113093917 113107768
CGIB: 127964047 128018591
PTET: 122350397(rimkla)
LROH: 127170090(rimkla)
GRF: 141287159(rimkla)
OMC: 131545407(rimkla)
PPRM: 120483739(rimkla)
RKG: 130094558(rimkla)
MAMB: 125279787(rimkla)
CIDE: 127517732
CERY: 137027117(rimkla)
MASI: 127414466 127424193
TROS: 130567859(rimkla)
TDW: 130439951(rimkla)
MANU: 129413961(rimkla)
PDAB: 135729453(rimkla)
IPU: 108265850
IFU: 128607997(rimkla)
PHYP: 113529230
SMEO: 124399561(rimkla)
TFD: 113655760(rimkla)
TVC: 132853464(rimkla)
CGAR: 128530413(rimkla)
NGRA: 132893232(rimkla)
TRN: 134318214(rimkla)
AMEX: 103035057(rimkla)
CMAO: 118813696(rimkla)
EEE: 113572086
CHAR: 105902183(rimkla)
SPIL: 134087340(rimkla)
ASAD: 121712880(rimkla)
TRU: 101062827
TFS: 130530628(rimkla)
TNG: GSTEN00013753G001
LCO: 104920219
NCC: 104955181(rimkla)
TBEN: 117494141(rimkla)
CGOB: 115011073
PGEO: 117449663(rimkla)
GACU: 117541819(rimkla)
EMAC: 134870674(rimkla)
ELY: 117258509(rimkla)
EFO: 125891718(rimkla)
PLEP: 121947276(rimkla)
SLUC: 116040663(rimkla)
SVIT: 144520736(rimkla)
ECRA: 117948232(rimkla)
ESP: 116692402
PFLV: 114558866
PFLT: 120558683(rimkla)
GAT: 120828693(rimkla)
PPUG: 119222662(rimkla)
AFB: 129100051(rimkla)
CLUM: 117732964(rimkla)
PSWI: 130199585(rimkla)
CANA: 137800381(rimkla)
CVE: 137889322(rimkla)
AMIR: 142948848(rimkla)
MSAM: 119905637(rimkla)
SCHU: 122882832(rimkla)
EARM: 139289516(rimkla)
CUD: 121518035(rimkla)
SPUL: 138590367(rimkla)
LMIX: 132989383(rimkla)
HTC: 141799542(rimkla)
ALAT: 119022909(rimkla)
ASTR: 137611234(rimkla)
PKLU: 139210026(rimkla)
MZE: 101477475(rimkla)
ONL: 100698845
OAU: 116309725(rimkla)
OLA: 101169452(rimklb)
OML: 112159079(rimkla)
CSAI: 133457317(rimkla)
XMA: 102218635
XCO: 114141086
XHE: 116725681
PRET: 103467997(rimkla)
PFOR: 103138952(rimkla)
PLAI: 106957454(rimkla)
PMEI: 106907435(rimkla)
GAF: 122836233(rimkla)
PPRL: 129372418(rimkla)
CVG: 107088869(rimkla)
CTUL: 119797064(rimkla)
GMU: 124867677(rimkla)
NFU: 107390714
KMR: 108236831(rimkla)
ALIM: 106524174
NWH: 119417065(rimkla)
LTU: 140272080(rimkla)
AOCE: 111585273(rimkla)
EJA: 138192771(rimkla)
BFRE: 138615433(rimkla)
MCEP: 124997852(rimkla)
CSEM: 103384935
POV: 109630621(rimkla)
SSEN: 122776960(rimkla)
SSOE: 131468340(rimkla)
HHIP: 117764653(rimkla)
HSP: 118110963(rimkla)
PPLT: 128442387(rimkla)
SMAU: 118317585(rimkla)
LCF: 108891717
SDU: 111219047
SLAL: 111670604
XGL: 120804092(rimkla)
HCQ: 109526583
SSCV: 125988093(rimkla)
SBIA: 133508604(rimkla)
PEE: 133405192(rimkla)
PTAO: 133482673(rimkla)
BPEC: 110161111
ENY: 140362622(rimkla)
MALB: 109970719
BSPL: 114858903(rimkla)
SJO: 128357364(rimkla)
SSCO: 133988051(rimkla)
TTY: 137184314(rimkla)
GMH: 115542815
SASA: 106567384 106572158
STRU: 115166047 115168921
OTW: 112215953 112221609
OMY: 110491822 110532211
OGO: 124017459 124031877
ONE: 115102623 115132092
OKI: 109869491 109907940
OKE: 118360188 118361096
OMM: 135504472 135528563
OCLA: 139368314 139416442
SALP: 111966388 111976646
SNH: 120059373 120060966
SFON: 129824174 129830218
CCLU: 121538272 121545958
ELS: 105013808
OEP: 134019365(rimkla)
SFM: 108918203 108924922
PKI: 111856970 111859075(rimkla)
AANG: 118208179(rimkla)
AROT: 135233914(rimkla)
CCOG: 133139031(rimkla)
LOC: 102687393(rimkla)
PSPA: 121296514 121325367 121328885 121329280
ARUT: 117424072 117425213 117425745 117432003
PSEX: 120530966(rimkla) 120535665
LCM: 102351441(RIMKLB) 102354509(RIMKLA)
CMK: 103190080(rimkla)
RTP: 109924989(rimkla)
CPLA: 122540248(rimkla)
HOC: 132833521(rimkla)
LERI: 129711474(rimkla)
HAKA: 140718279(rimkla)
PMRN: 116937615 116948844
LRJ: 133345229
 » show all
Reference
1  [PMID:20657015]
  Authors
Collard F, Stroobant V, Lamosa P, Kapanda CN, Lambert DM, Muccioli GG, Poupaert JH, Opperdoes F, Van Schaftingen E
  Title
Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.
  Journal
J Biol Chem 285:29826-33 (2010)
DOI:10.1074/jbc.M110.152629
  Sequence
[mmu:108653]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.1.17
IUBMB Enzyme Nomenclature: 6.3.1.17
ExPASy - ENZYME nomenclature database: 6.3.1.17
BRENDA, the Enzyme Database: 6.3.1.17
LinkDB

KEGG   REACTION: R10677
Entry
R10677                      Reaction                               
Name
citrate:L-glutamate ligase (ADP-forming)
Definition
ATP + Citrate + L-Glutamate <=> ADP + Orthophosphate + beta-Citryl-L-glutamate
Equation
C00002 + C00158 + C00025 <=> C00008 + C00009 + C20775
Reaction class
RC00002  C00002_C00008
RC00064  C00025_C20775
RC03233  C00158_C20775
Enzyme
6.3.1.17
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.1  Acid-D-ammonia (or amine) ligases (amide synthases)
    6.3.1.17
     R10677  ATP + Citrate + L-Glutamate <=> ADP + Orthophosphate + beta-Citryl-L-glutamate
Orthology
K18310  beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41]
Other DBs
RHEA: 40046
LinkDB

DBGET integrated database retrieval system