KEGG ORTHOLOGY: K18366

ORTHOLOGY: K18366

Entry

K18366                      KO

Symbol

bphJ, xylQ, nahO, tesF

Name

acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]

Pathway

map00362

Benzoate degradation

map00620

Pyruvate metabolism

map00621

Dioxin degradation

map00622

Xylene degradation

map00650

Butanoate metabolism

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00569

Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA

Reaction

R00228

acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)

R01172

butanal:NAD+ oxidoreductase (CoA-acylating)

R09097

propanal:NAD+ oxidoreductase (CoA-propanoylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
   00650 Butanoate metabolism
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
   00622 Xylene degradation
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
   00621 Dioxin degradation
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.10  acetaldehyde dehydrogenase (acetylating)
     K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
    1.2.1.87  propanal dehydrogenase (CoA-propanoylating)
     K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
Dioxygenases [br01602.html]
Dioxygenases in aromatic ring cleavage
  K18366

Other DBs

COG:

COG4569

GO:

0008774

Genes

PATR:

EV46_07230

PATO:

GZ59_14670(nahO)

PSD:

DSC_09370

LSY:	H8L67_00475

RGL:	CS053_01765

RTH:	LRK53_10285

RBD:	ALSL_0878 ALSL_1081

VAF:	D1115_22445

PRE:	PCA10_13830

PFUW:

KF707C_12180 KF707C_16060(salG) KF707C_16240(bphX2)

PPI:	ND085(nahO)

PPUT:

L483_14060

PPUN:

PP4_27270(mhpF)

PVR:	PverR02_11590 PverR02_14705

PPUU:

PputUW4_01661(mhpF)

PKC:	PKB_4238(nahO)

PFZ:	AV641_10530

PLQ:	AA042_19760

PALK:

PSAKL28_05970

PPSY:

AOC04_07830

PFK:	PFAS1_28770

PSET:

THL1_1434

PSIL:

PMA3_11730

PKE:	DLD99_14745

PALL:

UYA_06975 UYA_07055

PUM:	HGP31_20765

PPSH:

G5J76_13485

PLAL:

FXN65_06425

PAZE:

KSS91_19290

PTAE:

NCTC10697_02056(bphJ)

PCAV:

D3880_17510

PPHN:

HU825_04965 HU825_14760

PIZ:	LAB08_R40960

PKM:	PZ739_11540

PSHS:

JJN09_05430

PFOU:

OZ911_14075

PSKP:

KU43P_19450(mhpF_1)

PSC:	A458_06515

PSTU:

UIB01_22745

PBM:	CL52_14715

SDEG:

GOM96_01765

AVN:	Avin_30580(lapF)

AVL:	AvCA_30580(lapF)

AVD:	AvCA6_30580(lapF)

HARR:

HV822_17980

PPHA:

BVH74_17965

HASM:

QAO71_12435

MARJ:

MARI_05450(bphJ)

MSHE:

MAALD49_03440(mhpF)

KAK:	Kalk_07860

ALC:	OTEC02_08815

AEI:	AOY20_01980

ASJ:	AsACE_CH00351

ADV:	DJ533_16965

ARJ:	DOM24_01570

AWU:	BEN71_02685

ACUM:

C9E88_006010

ALW:	FOB21_11705

ATN:	FM020_13985

ACHI:

CDG60_02960

ALJ:	G8D99_13405

AWG:	GFH30_01710

ASHA:

G8E00_02250

ATG:	J4G44_04385

AVB:	RYU24_27160

ABOU:

ACBO_27750

ACIU:

A3K93_01260

APOT:

MZO21_10845

ATZ:	M5E07_14195

ACIE:

ACIG:

SPL:

SHL:

SWD:

COLW:

CBER:

THT:	E2K93_11205

PHA:	PSHAa2142(mhpF)

PTN:	PTRA_a2595(bphJ)

PNG:	PNIG_a2789(bphJ)

LAL:	AT746_01295

SALH:

HMF8227_02731(bphJ)

CJA:	CJA_1528(nahO)

CEG:	D0C16_06470

TTU:	TERTU_1282

SPOI:

IMCC21906_00396 IMCC21906_02715

SNAN:

I6N98_10795

STAW:

NCG89_14275

ZAL:	AZF00_03865 AZF00_11425 AZF00_17815

HJA:	BST95_09510

HALC:

EY643_13290

AFUS:

EYZ66_02680 EYZ66_12970

PAQM:

E0F26_07470

HMAR:

HVMH_0575(mhpF)

CYQ:	Q91_0509(nahO) Q91_1490

CZA:	CYCME_0970(nahO) CYCME_2102

CYY:	CPC19_05400 CPC19_10510

BLEP:

THIS:

AEH:

TBN:

MMW:	Mmwyl1_3802

MPRI:

MP3633_3150

MGEO:

CFI10_00430 CFI10_04965 CFI10_06045

MSEC:

LN244_04510 LN244_04770 LN244_11325

MRZ:	KDW95_00760

NCU:	F0U83_03050

NJP:	NEJAP_0672(mhpF)

NIK:	F5I99_02025 F5I99_10100 F5I99_10515

AJP:	AMJAP_2525 AMJAP_2998

EMP:	EZMO1_1318(tesF)

ASIM:

FE240_03465

ZDF:	AN401_14620

SOK:	D0B54_06195

SINI:

GT972_14665

FCE:	JN531_005835

GBI:	PG2T_09670

GPB:	HDN1F_27080(aphF)

NZO:	SAMEA4504057_0443(bphJ)

NCI:	NCTC10296_00918(bphJ)

NWD:	H3L96_04780

NDU:	LVJ88_00575

VFF:	VITFI_CDS1375

PTES:

JQU52_04845

USU:	LVJ78_03645

AQL:	BXU06_16255 BXU06_16880 BXU06_17060

RPI:

Rpic_4618

RPF:	Rpic12D_3542

RIN:	ACS15_4355

REH:	H16_B0596(h16_B0596)

CNC:	CNE_2c05410

CUH:	BJN34_24655

RME:	Rmet_1320(mhpF)

CTI:	RALTA_B0400(mhpF)

CBW:	RR42_s2314

COX:	E0W60_08020

CCAX:

KZ686_10000

CUK:	KB879_20420

BVI:	Bcep1808_7604

BUR:	Bcep18194_B1458 Bcep18194_B2960

BCJ:	BCAM1614(mhpF)

BCEN:

DM39_3382 DM39_4833

BCEO:

I35_5474(mhpF)

BCT:	GEM_4110 GEM_5402

BCED:

DM42_4992 DM42_6344

BCEP:

APZ15_31150

BPYR:

ABD05_27815

BCON:

NL30_04135 NL30_24595

BDF:	WI26_15990 WI26_21150

BTEI:

WS51_00565 WS51_05700

BPSL:

WS57_06040 WS57_12160

BMEC:

WJ16_26795

BSTL:

BBJ41_10515 BBJ41_21345

BANN:

JFN94_19130 JFN94_25655

BARI:

NLX30_30180

BAEN:

L3V59_21745 L3V59_30400

BUQ:	AC233_11190

BURK:

DM992_32620

BXE:	Bxe_C1188(bphJ)

BXB:

DR64_8617

BFN:

OI25_4590

PARB:

CJU94_37875 CJU94_38120

PCAF:

PMEG:

PBRY:

PPAI:

PHUN:

PPK:	U875_01895

PRB:	X636_07575

CABA:

SBC2_49010(bphJ)

LIMN:

HKT17_03825

AXY:	AXYL_04308

APES:

FOC84_00310

AALN:

Q3V95_01640

CDN:	BN940_14426

RFR:

Rfer_0455

RLH:	MIZ03_0649 MIZ03_1025

PNA:

AJS:

ACID:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VBO:	CKY39_28500

VAV:	IG196_08135

CTT:	CtCNB1_1352 CtCNB1_3148

CTES:

O987_07735

COF:	FOZ74_08310

CRJ:	QMY55_07015

ADN:	Alide_0338

ADK:	Alide2_0283

OTD:	J1M35_00050

HYL:	LPB072_18195

HPSE:

HPF_01855(bphJ)

HYN:	F9K07_02770 F9K07_11455

HTN:	KI616_01950

DIH:	G7047_09700

SIMP:

C6571_13620

MELA:

C6568_07855

MJE:	LVC68_01010

STHM:

IS481_10545

SAQA:

OMP39_09125

MPT:	Mpe_A2267 Mpe_A3322

METP:

C1M51_06445 C1M51_16315

SNN:	EWH46_19315

SMIO:

CATMQ487_04060(mhpF_1) CATMQ487_17580 CATMQ487_31620(mhpF_2)

IDC:	LRM40_19580

LCH:

Lcho_3341

JAJ:	EKL02_01795 EKL02_13155

MASW:

AM586_18655

TMJ:	P0M04_30660

RBU:	PG1C_14095

ABRE:

pbN1_20570(mhpF)

DAR:	Daro_0906 Daro_1355 Daro_3783 Daro_3807

DEY:	HYN24_14115 HYN24_14205

DDEN:

KI615_16875

QAU:	KI612_15150

FLE:	KI610_08590 KI610_13430 KI610_15455

AZO:	azo1856(lapF) azo1973(mhpF) azo2432(nahO)

AOA:	dqs_2009 dqs_2128 dqs_2576

AZI:	AzCIB_1508 AzCIB_4410

AZD:	CDA09_09960 CDA09_10330 CDA09_10455 CDA09_21435

AZR:	CJ010_12265 CJ010_12840 CJ010_15210

TMZ:	Tmz1t_2078 Tmz1t_3106

THU:	AC731_001815 AC731_008900

THAU:

C4PIVTH_2808(mhpF) C4PIVTH_4320(mhpF) C4PIVTH_4381(mhpF)

THK:	CCZ27_04600 CCZ27_10755

THAG:

CKCBHOJB_01547(bphJ_1) CKCBHOJB_02380(bphJ_2)

AZQ:	G3580_00545 G3580_08275

ACOM:

CEW83_03605

NPM:	QEO92_31655

SHZ:

shn_33315

CID:

P73_1381

DAA:	AKL17_3p0138

TEC:	AKL02_008265

PGV:	SL003B_p0057

NPP:	PP1Y_AT32733

SGI:	SGRAN_1580(mhpF)

SJP:	SJA_C1-11900(mhpF)

SINB:

SIDU_08315

SYB:	TZ53_09025 TZ53_23470

SHYD:

CJD35_06510

SUFL:

FIL70_18990

SBAR:

H5V43_20640

SFLA:

SPHFLASMR4Y_02367(bphJ)

SPHJ:

BSL82_10440

ALTN:

LBX01_06755

PMAS:

NCF86_10600

TFV:	IDJ81_04965

TXI:

TH3_21413

HTL:

HPTL_0048

ACIB:

ACBT_0260(dmpF)

AFC:	AFAEC_1845(dmpF)

AAQI:

AAQM_0981(dmpF)

ACLO:

ACLO_a0140(dmpF)

ADZ:	ADFLV_2552(dmpF)

ARC:

ABLL_2443

AROS:

NJU99_01645

ALK:	ALEK_0382(dmpF)

AANA:

AANAER_1259(dmpF)

BSM:	BSM4216_0948

BACI:

B1NLA3E_08430 B1NLA3E_09190 B1NLA3E_13975

BACQ:

DOE78_09225

BHK:	B4U37_13940

OCN:	CUC15_03675

GJF:	M493_00040

PARG:

PspKH34_15470

LGY:	T479_19650

LYZ:	DCE79_01750

LYG:	C1N55_08070

VIG:	BKP57_09385

VNT:	OLD84_14185

VIK:	KFZ58_14505

LAO:	AOX59_17245

BSJ:	UP17_10520

PFRI:

L8956_11385

PRD:	F7984_12030

RUE:	DT065_13785 DT065_15200

SALE:

EPH95_15035

SIV:

SSIL_0067

SSIL:

SOLI23_18500 SOLI23_19600

SOB:	CSE16_14635

PLL:	I858_008615

PLIQ:

QWY22_10470 QWY22_17945

PSHE:

QWY16_03555 QWY16_10570 QWY16_17805

PSHX:

QWY21_10865 QWY21_17790

KZO:	NCTC404_01742(bphJ)

SPOO:

J3U78_11180

CFM:	BJL90_19995

DCA:	Desca_1928

LACY:

A4V08_07735

MTHO:

MOTHE_c17900

MTHZ:

MOTHA_c18730

STED:

SPTER_02990(bphJ_1) SPTER_36970(bphJ_2)

SSPH:

SPSPH_044550(bphJ)

MMUC:

SPAV:

SAQ:

CWO:

Reference

PMID:16151114

Authors

Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T

Title

Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.

Journal

Appl Environ Microbiol 71:5275-81 (2005)
DOI:10.1128/AEM.71.9.5275-5281.2005

Sequence

[ctt:CtCNB1_1352]

LinkDB

ENZYME: 1.2.1.87

Entry

EC 1.2.1.87                 Enzyme

Name

propanal dehydrogenase (CoA-propanoylating);
BphJ

Class

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

Sysname

propanal:NAD+ oxidoreductase (CoA-propanoylating)

Reaction(IUBMB)

propanal + CoA + NAD+ = propanoyl-CoA + NADH + H+ [RN:R09097]

Reaction(KEGG)

R09097;
(other) R01172

Substrate

propanal [CPD:C00479];
CoA [CPD:C00010];
NAD+ [CPD:C00003]

Product

propanoyl-CoA [CPD:C00100];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

The enzyme forms a bifunctional complex with EC 4.1.3.43, 4-hydroxy-2-oxohexanoate aldolase, with a tight channel connecting the two subunits [1,2,3]. Also acts, more slowly, on glycolaldehyde and butanal. In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39, 4-hydroxy-2-oxovalerate aldolase. The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10, acetaldehyde dehydrogenase (acetylating). NADP+ can replace NAD+ with a much slower rate [3].

History

EC 1.2.1.87 created 2013

Pathway

ec00622

Xylene degradation

ec00640

Propanoate metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K13922

propionaldehyde dehydrogenase

K18366

acetaldehyde/propanal dehydrogenase

Genes

ECG:	E2348C_2143(pduP)

ECW:	EcE24377A_2292(pduP)

ECV:	APECO1_2291(eutE)

ECQ:	ECED1_3458

EUM:	ECUMN_2347

ECZ:	ECS88_4675

ECC:

c4534

ELN:	NRG857_10215

ELF:

LF82_343

EFE:

EFER_2021

EMA:	C1192_01885

ESZ:	FEM44_24955(pduP)

ERUY:

OSH18_00545(pduP)

STY:	STY2256(pduP)

STT:	t0823(pduP)

SEX:	STBHUCCB_8780

SENT:

TY21A_04180

STM:	STM2051(pduP)

SEO:	STM14_2540(pduP)

SEV:	STMMW_20811

SEY:	SL1344_2027(pduP)

SEM:	STMDT12_C20730

SEJ:	STMUK_2081(pduP)

SEB:	STM474_2136(pduP)

SEF:	UMN798_2216(pduP)

SETU:

STU288_06645

SETC:

CFSAN001921_06530

SENR:

STMDT2_20241(pduP)

SEND:

DT104_21081(pduP)

SENI:

CY43_11070

SEEN:

SE451236_16465

SPT:	SPA0820(pduP)

SEK:

SSPA0767

SPQ:	SPAB_01053

SEI:	SPC_1663(pduP)

SEC:	SCH_2059(pduP)

SEH:	SeHA_C2274

SHB:

SU5_02645

SENH:

CFSAN002069_21565

SEEH:

SEEH1578_19535

SEE:	SNSL254_A2228

SENN:

SN31241_31520

SEW:	SeSA_A2221

SEA:	SeAg_B2174

SENS:

Q786_10125

SED:

SeD_A2387

SEG:	SG2080(pduP)

SEL:	SPUL_0849(pduP)

SEGA:

SPUCDC_0849(pduP)

SET:	SEN2049(pduP)

SENA:

AU38_10340

SENO:

AU37_10350

SENV:

AU39_10350

SENQ:

AU40_11595

SENL:

IY59_10635

SENJ:

CFSAN001992_01180

SEEC:

CFSAN002050_17215

SEEB:

SEEB0189_009210

SEEP:

I137_03830

SENB:

BN855_21360

SENE:

IA1_10235

SENC:

SEET0819_17400

SES:	SARI_00836

SALZ:

EOS98_08755

SSN:	SSON_2071(pduP)

KPN:	KPN_03216(pduP)

KPU:	KP1_4485(pduP)

KPM:	KPHS_42790

KPP:

A79E_0893

KPH:	KPNIH24_07395

KPZ:	KPNIH27_20735

KPV:	KPNIH29_21505

KPW:	KPNIH30_21525

KPY:	KPNIH31_20790

KPG:	KPNIH32_22385

KPC:	KPNIH10_21320

KPQ:	KPR0928_20810

KPT:	VK055_4309

KPO:	KPN2242_19030

KPR:	KPR_1818(pduP)

KPJ:

N559_1023

KPI:	D364_16325

KPA:	KPNJ1_01028

KPS:	KPNJ2_01059

KPX:	PMK1_00697(adhE_2)

KPB:	FH42_12040

KPNE:

KU54_005045

KPNU:

LI86_05055

KPNK:

BN49_0892(pduP)

KVA:

Kvar_0854

KPE:	KPK_0899(pduP)

KPK:	A593_06210

KVD:	KR75_03660

KVQ:	SP68_10205

KOX:

KOX_01510

KOE:

A225_4767

KOY:	J415_08185

KOM:	HR38_27645

KOK:	KONIH1_23950

KOC:	AB185_12440

KQU:	AVR78_25830

KQV:	B8P98_04975

KLL:	BJF97_23780

KLW:	DA718_05410(pduP)

KAR:	LGL98_04555(pduP)

KGR:	JJJ10_05430(pduP)

KPAS:

LUW96_01605(pduP)

KLC:	K7H21_05095(pduP)

KLM:	BWI76_23170

REE:	electrica_01995(adhE_2)

ROR:	RORB6_03630

RPLN:

B1209_10115

RAO:	DSD31_10070

CRO:	ROD_21371(pduP)

CKO:

CKO_00785

CFD:	CFNIH1_21250

CBRA:

A6J81_01060

CWE:	CO701_07975

CYO:	CD187_09160

CPOT:

FOB25_20470(pduP)

CFQ:	C2U38_15370

CSED:

JY391_08735(pduP)

CAMA:

F384_10465

CAF:	AL524_12215

CIF:	AL515_09995

CFAR:

CI104_16250

CIR:	C2U53_26060

CIE:	AN232_13940

CPAR:

CUC49_05370

CTEL:

GBC03_14230(pduP)

CITZ:

E4Z61_02800(pduP)

CARS:

E1B03_16780(pduP)

CIX:	M4I31_09085(pduP)

CIB:	HF677_009335(pduP)

ESC:	Entcl_1746

KLE:	AO703_13215

BUF:	D8682_02430

BFT:	MNO13_13040

AHN:	NCTC12129_00739(eutE)

ASUB:

NLZ15_18905(grpJ)

KIN:	AB182_08085

PDZ:	HHA33_11210(pduP)

METY:

MRY16398_18470(pduP)

SUPE:

P0H77_17595

EBC:	C2U52_18670

EBU:	CUC76_20230

EBB:

F652_949

YEN:	YE2741(pduP)

YEP:	YE105_C1544

YEY:

Y11_16281

YEW:

CH47_2090

YET:

CH48_3140

YEF:	FORC2_2722

YEE:	YE5303_31741(pduP)

YAL:

AT01_4022

YFR:

AW19_708

YIN:

CH53_3356

YKR:

CH54_954

YAK:	ACZ76_01720

YMA:	DA391_08085

YHI:	D5F51_11565

YCA:	F0T03_14035

YMO:	HRD69_13100

YAS:	N0H69_17145

YKI:	HRD70_18685

RVC:	J9880_23725

RBON:

QNM34_08670

GQU:	AWC35_20645

PATR:

EV46_07230

PATO:

GZ59_14670(nahO)

PWA:	Pecwa_4095

PPAR:

A8F97_21010

PEC:

W5S_4254

PWS:	A7983_05610

SOD:	Sant_2129(eutE)

SLIG:

GTU79_14960

MINT:

C7M51_00183(adhE_2)

MTHI:

C7M52_02536(adhE_2)

HPAR:

AL518_16385

PSD:

DSC_09370

LSY:	H8L67_00475

RGL:	CS053_01765

RTH:	LRK53_10285

RBD:	ALSL_0878 ALSL_1081

VEJ:	VEJY3_08440

VAF:	D1115_22445

VAS:	GT360_18010

VZI:	G5S32_07725

VIB:	VspSTUT11_17390

PRE:	PCA10_13830

PFUW:

KF707C_12180 KF707C_16060(salG) KF707C_16240(bphX2)

PPI:	ND085(nahO)

PPUT:

L483_14060

PPUN:

PP4_27270(mhpF)

PVR:	PverR02_11590 PverR02_14705

PPUU:

PputUW4_01661(mhpF)

PKC:	PKB_4238(nahO)

PFZ:	AV641_10530

PLQ:	AA042_19760

PALK:

PSAKL28_05970

PPSY:

AOC04_07830

PFK:	PFAS1_28770

PSET:

THL1_1434

PSIL:

PMA3_11730

PKE:	DLD99_14745

PALL:

UYA_06975 UYA_07055

PUM:	HGP31_20765

PPSH:

G5J76_13485

PLAL:

FXN65_06425

PAZE:

KSS91_19290

PTAE:

NCTC10697_02056(bphJ)

PCAV:

D3880_17510

PPHN:

HU825_04965 HU825_14760

PIZ:	LAB08_R40960

PKM:	PZ739_11540

PSHS:

JJN09_05430

PFOU:

OZ911_14075

PSKP:

KU43P_19450(mhpF_1)

PSC:	A458_06515

PSTU:

UIB01_22745

PBM:	CL52_14715

SDEG:

GOM96_01765

AVN:	Avin_30580(lapF)

AVL:	AvCA_30580(lapF)

AVD:	AvCA6_30580(lapF)

HARR:

HV822_17980

PPHA:

BVH74_17965

HASM:

QAO71_12435

MARJ:

MARI_05450(bphJ)

MSHE:

MAALD49_03440(mhpF)

KAK:	Kalk_07860

ALC:	OTEC02_08815

AEI:	AOY20_01980

ASJ:	AsACE_CH00351

ADV:	DJ533_16965

ARJ:	DOM24_01570

AWU:	BEN71_02685

ACUM:

C9E88_006010

ALW:	FOB21_11705

ATN:	FM020_13985

ACHI:

CDG60_02960

ALJ:	G8D99_13405

AWG:	GFH30_01710

ASHA:

G8E00_02250

ATG:	J4G44_04385

AVB:	RYU24_27160

ABOU:

ACBO_27750

ACIU:

A3K93_01260

APOT:

MZO21_10845

ATZ:	M5E07_14195

ACIE:

KIP84_08185

ACIG:

BS636_03600

SPC:	Sputcn32_0199

SPL:

Spea_2117

SHW:	Sputw3181_0418

SHL:

Shal_2089

SWD:

Swoo_1391

COLW:

A3Q33_18580

CBER:

B5D82_11265

THT:	E2K93_11205

PHA:	PSHAa2142(mhpF)

PTN:	PTRA_a2595(bphJ)

PNG:	PNIG_a2789(bphJ)

LAL:	AT746_01295

SALH:

HMF8227_02731(bphJ)

CJA:	CJA_1528(nahO)

CEG:	D0C16_06470

TTU:	TERTU_1282

SPOI:

IMCC21906_00396 IMCC21906_02715

SNAN:

I6N98_10795

STAW:

NCG89_14275

ZAL:	AZF00_03865 AZF00_11425 AZF00_17815

HJA:	BST95_09510

HALC:

EY643_13290

AFUS:

EYZ66_02680 EYZ66_12970

PAQM:

E0F26_07470

HMAR:

HVMH_0575(mhpF)

CYQ:	Q91_0509(nahO) Q91_1490

CZA:	CYCME_0970(nahO) CYCME_2102

CYY:	CPC19_05400 CPC19_10510

BLEP:

AL038_01295

THIS:

HZT40_10610

AEH:

Mlg_2461

TBN:

TBH_C0929

MMW:	Mmwyl1_3802

MPRI:

MP3633_3150

MGEO:

CFI10_00430 CFI10_04965 CFI10_06045

MSEC:

LN244_04510 LN244_04770 LN244_11325

MRZ:	KDW95_00760

NCU:	F0U83_03050

NJP:	NEJAP_0672(mhpF)

NIK:	F5I99_02025 F5I99_10100 F5I99_10515

AJP:	AMJAP_2525 AMJAP_2998

EMP:	EZMO1_1318(tesF)

ASIM:

FE240_03465

TAU:

Tola_1697

ZDF:	AN401_14620

SOK:	D0B54_06195

SINI:

GT972_14665

FCE:	JN531_005835

GBI:	PG2T_09670

GPB:	HDN1F_27080(aphF)

NZO:	SAMEA4504057_0443(bphJ)

NCI:	NCTC10296_00918(bphJ)

NWD:	H3L96_04780

NDU:	LVJ88_00575

VFF:	VITFI_CDS1375

PTES:

JQU52_04845

USU:	LVJ78_03645

AQL:	BXU06_16255 BXU06_16880 BXU06_17060

RPI:

Rpic_4618

RPF:	Rpic12D_3542

RIN:	ACS15_4355

REH:	H16_B0596(h16_B0596)

CNC:	CNE_2c05410

CUH:	BJN34_24655

RME:	Rmet_1320(mhpF)

CTI:	RALTA_B0400(mhpF)

CBW:	RR42_s2314

COX:	E0W60_08020

CCAX:

KZ686_10000

CUK:	KB879_20420

BVI:	Bcep1808_7604

BUR:	Bcep18194_B1458 Bcep18194_B2960

BCJ:	BCAM1614(mhpF)

BCEN:

DM39_3382 DM39_4833

BCEO:

I35_5474(mhpF)

BCT:	GEM_4110 GEM_5402

BCED:

DM42_4992 DM42_6344

BCEP:

APZ15_31150

BPYR:

ABD05_27815

BCON:

NL30_04135 NL30_24595

BDF:	WI26_15990 WI26_21150

BTEI:

WS51_00565 WS51_05700

BPSL:

WS57_06040 WS57_12160

BMEC:

WJ16_26795

BSTL:

BBJ41_10515 BBJ41_21345

BANN:

JFN94_19130 JFN94_25655

BARI:

NLX30_30180

BAEN:

L3V59_21745 L3V59_30400

BUQ:	AC233_11190

BURK:

DM992_32620

BXE:	Bxe_C1188(bphJ)

BXB:

DR64_8617

BFN:

OI25_4590

PARB:

CJU94_37875 CJU94_38120

PCAF:

DSC91_003290

PMEG:

FNZ07_21160

PBRY:

NDK50_32880

PPAI:

E1956_37235

PHUN:

U0042_26775

PPK:	U875_01895

PRB:	X636_07575

CABA:

SBC2_49010(bphJ)

LIMN:

HKT17_03825

AXY:	AXYL_04308

APES:

FOC84_00310

AALN:

Q3V95_01640

CDN:	BN940_14426

RFR:

Rfer_0455

RLH:	MIZ03_0649 MIZ03_1025

PNA:

Pnap_4143

AJS:

Ajs_0223

ACID:

CBP33_01110

ACIP:

CBP36_01205

ACIN:

CBP34_01115

ACIS:

CBP35_17745

AMON:

H9L24_14180

VEI:

Veis_2782

VBO:	CKY39_28500

VAV:	IG196_08135

CTT:	CtCNB1_1352 CtCNB1_3148

CTES:

O987_07735

COF:	FOZ74_08310

CRJ:	QMY55_07015

ADN:	Alide_0338

ADK:	Alide2_0283

OTD:	J1M35_00050

HYL:	LPB072_18195

HPSE:

HPF_01855(bphJ)

HYN:	F9K07_02770 F9K07_11455

HTN:	KI616_01950

DIH:	G7047_09700

SIMP:

C6571_13620

MELA:

C6568_07855

MJE:	LVC68_01010

STHM:

IS481_10545

SAQA:

OMP39_09125

MPT:	Mpe_A2267 Mpe_A3322

METP:

C1M51_06445 C1M51_16315

SNN:	EWH46_19315

SMIO:

CATMQ487_04060(mhpF_1) CATMQ487_17580 CATMQ487_31620(mhpF_2)

IDC:	LRM40_19580

LCH:

Lcho_3341

JAJ:	EKL02_01795 EKL02_13155

MASW:

AM586_18655

TMJ:	P0M04_30660

RBU:	PG1C_14095

ABRE:

pbN1_20570(mhpF)

DAR:	Daro_0906 Daro_1355 Daro_3783 Daro_3807

DEY:	HYN24_14115 HYN24_14205

DDEN:

KI615_16875

QAU:	KI612_15150

FLE:	KI610_08590 KI610_13430 KI610_15455

AZO:	azo1856(lapF) azo1973(mhpF) azo2432(nahO)

AOA:	dqs_2009 dqs_2128 dqs_2576

AZI:	AzCIB_1508 AzCIB_4410

AZD:	CDA09_09960 CDA09_10330 CDA09_10455 CDA09_21435

AZR:	CJ010_12265 CJ010_12840 CJ010_15210

TMZ:	Tmz1t_2078 Tmz1t_3106

THU:	AC731_001815 AC731_008900

THAU:

C4PIVTH_2808(mhpF) C4PIVTH_4320(mhpF) C4PIVTH_4381(mhpF)

THK:	CCZ27_04600 CCZ27_10755

THAG:

CKCBHOJB_01547(bphJ_1) CKCBHOJB_02380(bphJ_2)

AZQ:	G3580_00545 G3580_08275

ACOM:

CEW83_03605

NPM:	QEO92_31655

SHZ:

shn_33315

RPC:

RPC_1174

CID:

P73_1381

RCP:	RCAP_rcc02201(adhE)

RSU:	NHU_00544(adhE)

RHM:	B5V46_15215

DAA:	AKL17_3p0138

TEC:	AKL02_008265

PGV:	SL003B_p0057

NPP:	PP1Y_AT32733

SGI:	SGRAN_1580(mhpF)

SJP:	SJA_C1-11900(mhpF)

SINB:

SIDU_08315

SYB:	TZ53_09025 TZ53_23470

SHYD:

CJD35_06510

SUFL:

FIL70_18990

SBAR:

H5V43_20640

SFLA:

SPHFLASMR4Y_02367(bphJ)

SPHJ:

BSL82_10440

ALTN:

LBX01_06755

PMAS:

NCF86_10600

TFV:	IDJ81_04965

RRU:

Rru_A0914

RRF:

F11_04715

TXI:

TH3_21413

HTL:

HPTL_0048

ACIB:

ACBT_0260(dmpF)

AFC:	AFAEC_1845(dmpF)

AAQI:

AAQM_0981(dmpF)

ACLO:

ACLO_a0140(dmpF)

ADZ:	ADFLV_2552(dmpF)

ARC:

ABLL_2443

AROS:

NJU99_01645

ALK:	ALEK_0382(dmpF)

AANA:

AANAER_1259(dmpF)

DAL:

Dalk_4987

MRM:	A7982_04322

HOH:

Hoch_5813

BBAE:

FRD01_01510

BSM:	BSM4216_0948

BSHI:

LGQ02_18580

BACI:

B1NLA3E_08430 B1NLA3E_09190 B1NLA3E_13975

BACQ:

DOE78_09225

BACA:

FAY30_13310

BHK:	B4U37_13940 B4U37_21085

OCN:	CUC15_03675

GMC:	GY4MC1_1873

GJF:	M493_00040

GTH:	Geoth_1939

PTL:	AOT13_13035

PARG:

PspKH34_15470

LGY:	T479_19650

LYZ:	DCE79_01750

LYG:	C1N55_08070

VIG:	BKP57_09385

VNT:	OLD84_14185

VIK:	KFZ58_14505

LAO:	AOX59_17245

BSJ:	UP17_10520

PFRI:

L8956_11385

PRD:	F7984_12030

RUE:	DT065_13785 DT065_15200

SALE:

EPH95_15035

NCM:	QNK12_17325

NNV:	QNH39_13905

LMO:

lmo1165

LMN:	LM5578_1238

LMY:	LM5923_1191

LMT:	LMRG_00608

LMOC:

LMOSLCC5850_1154(pduP)

LMOE:

BN418_1367

LMOB:

BN419_1365

LMOD:

LMON_1158

LMOW:

AX10_14330

LMOQ:

LM6179_01472

LMR:	LMR479A_1186(eutE)

LMOM:

IJ09_04510

LMF:	LMOf2365_1173(pduP)

LMC:	Lm4b_01170

LMOG:

BN389_11840(eutE)

LMP:

MUO_06020

LMOL:

LMOL312_1152(pduP)

LMOJ:

LM220_17082

LMOZ:

LM1816_08253

LMOX:

AX24_03195

LMH:	LMHCC_1486

LMQ:	LMM7_1171(pduP)

LML:	lmo4a_1148(pduP)

LMG:	LMKG_01769

LMS:

LMLG_1099

LMJ:	LMOG_00564

LMW:	LMOSLCC2755_1157(pduP)

LMX:	LMOSLCC2372_1160(pduP)

LMZ:	LMOSLCC2482_1204(pduP)

LMON:

LMOSLCC2376_1116(pduP)

LMOS:

LMOSLCC7179_1132(pduP)

LMOO:

LMOSLCC2378_1169

LMOY:

LMOSLCC2479_1161(pduP)

LMOT:

LMOSLCC2540_1143(pduP)

LMOA:

LMOATCC19117_1165(pduP)

LMOK:

CQ02_05990

LMV:	Y193_09910

LIN:

lin1129

LWE:	lwe1123(pduP)

LSG:	lse_1043(pduP)

LIV:

LIV_1097

LII:	JL52_05820

LIW:	AX25_05925

LIA:	JL58_05945

LIO:	JL53_06475

LMAR:

LAX80_005405

SIV:

SSIL_0067

SSIL:

SOLI23_18500 SOLI23_19600

SOB:	CSE16_14635

PLL:	I858_008615

PLIQ:

QWY22_10470 QWY22_17945

PSHE:

QWY16_03555 QWY16_10570 QWY16_17805

PSHX:

QWY21_10865 QWY21_17790

KZO:	NCTC404_01742(bphJ)

SPOO:

J3U78_11180

LRE:

Lreu_1735

LRF:

LAR_1623

LRU:	HMPREF0538_20921

LNG:	BSQ50_09370

LBR:

LVIS_1603

LBK:	LVISKB_1534

LNA:	RIN67_06085

LCY:	LC20004_04075

LPD:	AYR62_10165

PCE:	PECL_1370(pduP)

PACI:

A4V11_08150

LROS:

LROSL1_1559

LGN:	ABM34_00615

LGM:	LG542_00695

EAV:	EH197_11725

ERAF:

J9537_04855

VCP:	H9L18_05050 H9L18_05435

VHY:	G7082_00730

VIE:	OL234_05830

CBK:	CLL_A1748 CLL_A2134

CBT:

CLH_1846

CBE:	Cbei_3832 Cbei_4045 Cbei_4054

CBZ:	Cbs_3832 Cbs_4045 Cbs_4054

CBEI:

LF65_04317 LF65_04554 LF65_04563

CSR:	Cspa_c21450(eutE) Cspa_c56880

CSB:	CLSA_c22740(eutE) CLSA_c33640(ald)

CSQ:

CSCA_5280

CCK:	Ccar_06105 Ccar_14685

CEU:	A7L45_05685

CTAE:

BGI42_07385 BGI42_07955

CFM:	BJL90_19995

CCHV:

BTM20_07295

CDRK:

B9W14_18820

CDY:	F3K33_19585 F3K33_20700 F3K33_20745

CCOH:

SAMEA4530647_0801(sucD)

CGAS:

J1C67_05805

CCAA:

KQH81_03695 KQH81_03720

CMAH:

C1I91_22750

CNN:	CNEO_2844(eutE)

CINT:

HZF06_17650 HZF06_17695

CALE:

FDN13_09695 FDN13_12855

CPRF:

K7H06_13890

FPLA:

A4U99_10740

RUM:

CK1_20690

OVA:

OBV_17600

DCA:	Desca_1928

TFR:	BR63_18135

FWA:	DCMF_27365

AACX:

DEACI_1969

TJR:	TherJR_0630

ELM:

ELI_4072

EMT:	CPZ25_010665

ELIM:

B2M23_06190

AWO:	Awo_c25770(pduP)

AWI:	CHL1_000951

ACAE:

HYG86_04020

IBU:	IB211_01996c

ROB:

CK5_18240

BLAB:

EYS05_10205

BWX:	NQ550_05520

BMAS:

LK422_13470

BLUI:

Blut17040_26900

CPY:

Cphy_1178

LACY:

A4V08_01395 A4V08_01420 A4V08_07735

CSO:	CLS_23700 CLS_23750

LXA:	OW255_01210 OW255_01230

EHL:

EHLA_3029

PXV:	FXF36_06965 FXF36_06995

ACEL:

acsn021_21700

RGN:	RGna_15045

CBOL:

CGC65_23885 CGC65_23910

WHJ:	H9Q79_16945

LBX:	lbkm_1142 lbkm_1149

VGU:	HYG85_06815

AMIC:

Ami3637_01490

ABUT:

Ami103574_07470

ETM:	CE91St48_36280

GFE:	Gferi_18345 Gferi_26075

ROC:	HF520_07510

RHOM:

FRIFI_1259

TEX:	Teth514_1942

THX:

Thet_0994

GEK:	kuro4_24440 kuro4_26240

TTO:	Thethe_02116

TXY:	Thexy_2095

TSH:

Tsac_0219

MAS:	Mahau_0819 Mahau_0828

MTHO:

MOTHE_c17900

MTHZ:

MOTHA_c18730

TOC:

Toce_0560

HAS:	Halsa_0996

IFN:	GM661_12920

AFT:	BBF96_02150

KME:	H0A61_00535(sucD)

VDN:	NCTC11831_01740(sucD)

VNK:	VEIT17_16000

VRG:	OKW85_08425

PUF:

UFO1_1126

PFT:

JBW_03293

STED:

SPTER_02990(bphJ_1) SPTER_36970(bphJ_2)

SSPH:

SPSPH_010810(adhE_2) SPSPH_044550(bphJ)

SSID:

SPSIL_047060(sucD)

ERZ:	ER308_02900

MMUC:

C1S78_007400

SPAV:

Spa2297_32965

PFR:	PFREUD_09130(pduP)

PFRE:

RM25_1259

PACD:

EGX94_11970

PAUS:

NCTC13651_01469(adhE_2)

PPC:	HMPREF9154_2990

ARUB:

J5A65_14235

TEJ:	KDB89_01955

TLS:	QH948_12160

PROP:

QQ658_06750

SAQ:

Sare_4566

CWO:

Cwoe_4834

PBF:	CFX0092_A2147

BIP:

Bint_1611

MSIL:

METEAL_19450

FUS:	HMPREF0409_01360

FNE:	FSDG_02008

FHW:	RN87_00245

FUL:	C4N20_01445

FCI:	I6I83_03175

FPOL:

ERS445057_00525(adhE_1)

IPO:	Ilyop_2358

STR:	Sterm_1037

CPOR:

BED41_08950

SBR:

SY1_15720

TLI:

Tlie_0209

AMO:	Anamo_0127

ARAM:

KAR29_11995

ALAM:

RT761_00620(adhE)

» show all

Reference

1 [PMID:19476337]

Authors

Baker P, Pan D, Carere J, Rossi A, Wang W, Seah SY

Title

Characterization of an aldolase-dehydrogenase complex that exhibits substrate channeling in the polychlorinated biphenyls degradation pathway.

Journal

Biochemistry 48:6551-8 (2009)
DOI:10.1021/bi9006644

Sequence

[bxe:Bxe_C1188]

Reference

2 [PMID:21838275]

Authors

Carere J, Baker P, Seah SY

Title

Investigating the molecular determinants for substrate channeling in BphI-BphJ, an aldolase-dehydrogenase complex from the polychlorinated biphenyls degradation pathway.

Journal

Biochemistry 50:8407-16 (2011)
DOI:10.1021/bi200960j

Sequence

[bxe:Bxe_C1188]

Reference

3 [PMID:22316175]

Authors

Baker P, Hillis C, Carere J, Seah SY

Title

Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes.

Journal

Biochemistry 51:1942-52 (2012)
DOI:10.1021/bi201832a

Sequence

[ttj:TTHB247]

Other DBs

ExplorEnz - The Enzyme Database:

1.2.1.87

IUBMB Enzyme Nomenclature:

1.2.1.87

ExPASy - ENZYME nomenclature database:

1.2.1.87

BRENDA, the Enzyme Database:

1.2.1.87

LinkDB

REACTION: R09097

Entry

R09097                      Reaction

Name

propanal:NAD+ oxidoreductase (CoA-propanoylating)

Definition

Propanal + NAD+ + CoA <=> Propanoyl-CoA + NADH + H+

Equation

C00479 + C00003 + C00010 <=> C00100 + C00004 + C00080

Reaction class

RC00001

C00003_C00004

RC00004

C00010_C00100

RC00184

C00100_C00479

Enzyme

1.2.1.87

Pathway

rn00622

Xylene degradation

rn00640

Propanoate metabolism

rn01100

Metabolic pathways

rn01120

Microbial metabolism in diverse environments

rn01220

Degradation of aromatic compounds

Module

M00569

Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.87
     R09097  Propanal + NAD+ + CoA <=> Propanoyl-CoA + NADH + H+

Orthology

K13922

propionaldehyde dehydrogenase [EC:1.2.1.87]

K18366

acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]

Other DBs

RHEA:

36030

LinkDB

DBGET integrated database retrieval system