KEGG   ORTHOLOGY: K18653
Entry
K18653                      KO                                     
Symbol
ntdA
Name
3-dehydro-glucose-6-phosphate---glutamate transaminase [EC:2.6.1.104]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00877  Kanosamine biosynthesis, glucose 6-phosphate => kanosamine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K18653  ntdA; 3-dehydro-glucose-6-phosphate---glutamate transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.104  3-dehydro-glucose-6-phosphate---glutamate transaminase
     K18653  ntdA; 3-dehydro-glucose-6-phosphate---glutamate transaminase
Other DBs
RN: R10698
COG: COG0399
Genes
ECV: APECO1_O1CoBM86
YEL: LC20_02629
EAM: EAMY_0627(yhjL)
EAY: EAM_2803(ntdA)
EPY: EpC_29560
EPR: EPYR_03197(yhjL)
ERJ: EJP617_17800
XBV: XBW1_3412(ntdA)
RHEY: FEE42_04990
BSU: BSU10550(ntdA)
BSR: I33_1189
BSL: A7A1_3679
BSH: BSU6051_10550(ntdA)
BSUT: BSUB_01152(ntdA)
BSUL: BSUA_01152(ntdA)
BSUS: Q433_05970
BSO: BSNT_07499(yhjL)
BSQ: B657_10550(ntdA)
BSX: C663_1079(ntdA)
BSS: BSUW23_05350(ntdA)
BST: GYO_1359
BLI: BL03980(ntdA)
BLD: BLi03946(ntdA)
BLH: BaLi_c39610(ntdA)
BSON: S101395_00443(ntdA)
BMOJ: HC660_11110(ntdA)
BAT: BAS3048
BCX: BCA_3326
BCF: bcf_16050
BTL: BALH_2925
BTW: BF38_4422
BPU: BPUM_0280
BPUM: BW16_01755
BPUS: UP12_01730
BACW: QR42_01710
BACY: QF06_04210
BACL: BS34A_11690(ntdA)
BALM: BsLM_1098
MAB: MAB_2610
MABB: MASS_2568
 » show all
Reference
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10550]
LinkDB

KEGG   ENZYME: 2.6.1.104
Entry
EC 2.6.1.104                Enzyme                                 
Name
3-dehydro-glucose-6-phosphate---glutamate transaminase;
3-oxo-glucose-6-phosphate:glutamate aminotransferase;
ntdA (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
kanosamine 6-phosphate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
kanosamine 6-phosphate + 2-oxoglutarate = 3-dehydro-D-glucose 6-phosphate + L-glutamate [RN:R10698]
Reaction(KEGG)
R10698
Substrate
kanosamine 6-phosphate [CPD:C12213];
2-oxoglutarate [CPD:C00026]
Product
3-dehydro-D-glucose 6-phosphate [CPD:C20668];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. The enzyme, found in the bacterium Bacillus subtilis, is involved in a kanosamine biosynthesis pathway.
History
EC 2.6.1.104 created 2014
Pathway
ec00998  Biosynthesis of various antibiotics
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K18653  3-dehydro-glucose-6-phosphate---glutamate transaminase
Genes
ECVAPECO1_O1CoBM86
YELLC20_02629
EAMEAMY_0627(yhjL)
EAYEAM_2803(ntdA)
EPYEpC_29560
EPREPYR_03197(yhjL)
ERJEJP617_17800
XBVXBW1_3412(ntdA)
RHEYFEE42_04990
BSUBSU10550(ntdA)
BSRI33_1189
BSLA7A1_3679
BSHBSU6051_10550(ntdA)
BSYI653_05335
BSUTBSUB_01152(ntdA)
BSULBSUA_01152(ntdA)
BSUSQ433_05970
BSOBSNT_07499(yhjL)
BSNBSn5_17160
BSQB657_10550(ntdA)
BSXC663_1079(ntdA)
BSPU712_05390
BSSBSUW23_05350(ntdA)
BSTGYO_1359
BLIBL03980(ntdA)
BLDBLi03946(ntdA)
BLHBaLi_c39610(ntdA)
BSONS101395_00443(ntdA)
BHTDIC78_04330
BMOJHC660_11110(ntdA)
BTEQG4P54_05595
BATBAS3048
BAHBAMEG_1338 BAMEG_1339
BAXH9401_3125 H9401_3126
BANSBAPAT_3142 BAPAT_3143
BANVDJ46_2023 DJ46_2024
BCUBCAH820_3273
BCXBCA_3326
BCFbcf_16050
BTLBALH_2925
BTHTH175_233p030
BTWBF38_4422
BWDCT694_13230
BMOBMLA2C4_13365
BPUBPUM_0280
BPUMBW16_01755
BPUSUP12_01730
BACWQR42_01710
BACYQF06_04210
BACLBS34A_11690(ntdA)
BALMBsLM_1098
BXIBK049_06530
BALTCFN77_01755
BSAFBSL056_01695
BITBIS30_15985
BGIBGM20_20550
SMUSC7J88_03315
SCHRDWB92_11000
SFFFOB90_09095
PCHIPC41400_15410
MABMAB_2610
MMVMYCMA_1411
MABBMASS_2568
MABLMMASJCM_2587
MIZBAB75_14135
MSAOMYCSP_09820
SMASAVERM_834
SHAWCEB94_31530
SVDCP969_03730
 » show all
Reference
1  [PMID:19342798]
  Authors
van Straaten KE, Langill DM, Palmer DR, Sanders DA
  Title
Purification, crystallization and preliminary X-ray analysis of NtdA, a putative  pyridoxal phosphate-dependent aminotransferase from Bacillus subtilis.
  Journal
Acta Crystallogr Sect F Struct Biol Cryst Commun 65:426-9 (2009)
DOI:10.1107/S1744309109009038
Reference
2  [PMID:23586652]
  Authors
Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR
  Title
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
  Journal
J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255
  Sequence
[bsu:BSU10550]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.104
IUBMB Enzyme Nomenclature: 2.6.1.104
ExPASy - ENZYME nomenclature database: 2.6.1.104
BRENDA, the Enzyme Database: 2.6.1.104
LinkDB

KEGG   REACTION: R10698
Entry
R10698                      Reaction                               
Name
kanosamine-6-phosphate:2-oxoglutarate aminotransferase
Definition
Kanosamine 6-phosphate + 2-Oxoglutarate <=> 3-Dehydro-D-glucose 6-phosphate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026
RC00781  C12213_C20668
Enzyme
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00877  Kanosamine biosynthesis, glucose 6-phosphate => kanosamine
Orthology
K18653  3-dehydro-glucose-6-phosphate---glutamate transaminase [EC:2.6.1.104]
Other DBs
RHEA: 37554
LinkDB

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