| Entry |
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| Definition |
5 ATP + 3 L-4-Hydroxyphenylglycine + L-Arginine + L-Serine + H2O <=> 5 AMP + 5 Diphosphate + Nocardicin G + L-4-Hydroxyphenylglycyl-L-arginine
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| Equation |
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| Comment |
nocardicin nonribosomal peptide synthetase
(1) 3 L-pHPG + L-Arg + L-Ser + 5 ATP <=> Pro-nocardicin G + 5 AMP + 5 Diphosphate
(2) Pro-nocardicin G + H2O <=> Nocardicin G + L-pHPG-L-Arg
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| Reaction class |
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| Pathway |
| rn01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00736 | Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A |
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| Orthology |
| K19102 | nocardicin nonribosomal peptide synthetase NocA |
| K19103 | nocardicin nonribosomal peptide synthetase NocB |
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| Reference |
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| Authors |
Gaudelli NM, Long DH, Townsend CA |
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| Title |
beta-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis. |
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| Journal |
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| Reference |
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| Authors |
Gaudelli NM, Townsend CA |
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| Title |
Epimerization and substrate gating by a TE domain in beta-lactam antibiotic biosynthesis. |
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| Journal |
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| LinkDB |
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