Entry
Symbol
elmMI
Name
8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase [EC:
2.1.1.305 ]
Pathway
map01057 Biosynthesis of type II polyketide products
map01110 Biosynthesis of secondary metabolites
Module
M00784 Elloramycin biosynthesis, 8-demethyltetracenomycin C => elloramycin A
Reaction
R10956 S-adenosyl-L-methionine:8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01057 Biosynthesis of type II polyketide products
K19567 elmMI; 8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K19567 elmMI; 8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase
Enzymes [BR:ko01000 ]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.305 8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase
K19567 elmMI; 8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008 ]
Polyketide tailoring proteins
Methylase
K19567 elmMI; 8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase
BRITE hierarchy
Genes
Taxonomy UniProt
Reference
Authors
Patallo EP, Blanco G, Fischer C, Brana AF, Rohr J, Mendez C, Salas JA
Title
Deoxysugar methylation during biosynthesis of the antitumor polyketide elloramycin by Streptomyces olivaceus. Characterization of three methyltransferase genes.
Journal
Sequence
LinkDB
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