KEGG   ORTHOLOGY: K19570
Entry
K19570            Tight     KO                                     
Symbol
elmD
Name
8-demethyl-8-(2,3,4-trimethoxy-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase [EC:2.1.1.-]
Pathway
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00784  Elloramycin biosynthesis, 8-demethyltetracenomycin C => elloramycin A
Reaction
R10959  S-adenosyl-L-methionine:8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K19570  elmD; 8-demethyl-8-(2,3,4-trimethoxy-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K19570  elmD; 8-demethyl-8-(2,3,4-trimethoxy-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K19570  elmD; 8-demethyl-8-(2,3,4-trimethoxy-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase
Genes
AG: CAP12593(elmD)
Reference
PMID:18310024
  Authors
Ramos A, Lombo F, Brana AF, Rohr J, Mendez C, Salas JA
  Title
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.
  Journal
Microbiology 154:781-8 (2008)
DOI:10.1099/mic.0.2007/014035-0
  Sequence
[ag:CAP12593]
LinkDB

KEGG   REACTION: R10959
Entry
R10959                      Reaction                               
Name
S-adenosyl-L-methionine:8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase
Definition
S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + Elloramycin A
Equation
C00019 + C20977 <=> C00021 + C12381
Reaction class
RC00003  C00019_C00021
RC01324  C12381_C20977
Enzyme
2.1.1.-
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00784  Elloramycin biosynthesis, 8-demethyltetracenomycin C => elloramycin A
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R10959  S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + Elloramycin A
Orthology
K19570  8-demethyl-8-(2,3,4-trimethoxy-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase [EC:2.1.1.-]
LinkDB

DBGET integrated database retrieval system