KEGG   ORTHOLOGY: K19630
Entry
K19630            Tight     KO                                     
Symbol
tsaC1
Name
4-formylbenzenesulfonate dehydrogenase [EC:1.2.1.62]
Pathway
map00623  Toluene degradation
map01120  Microbial metabolism in diverse environments
Reaction
R05272  4-formylbenzenesulfonate:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00623 Toluene degradation
    K19630  tsaC1; 4-formylbenzenesulfonate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.62  4-formylbenzenesulfonate dehydrogenase
     K19630  tsaC1; 4-formylbenzenesulfonate dehydrogenase
Other DBs
GO: 0018482
Genes
AG: AAC44807(tsaC1)
Reference
PMID:8828208
  Authors
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM
  Title
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.
  Journal
Microbiology 142 ( Pt 9):2419-27 (1996)
DOI:10.1099/00221287-142-9-2419
  Sequence
[ag:AAC44807]
LinkDB

KEGG   ENZYME: 1.2.1.62
Entry
EC 1.2.1.62                 Enzyme                                 
Name
4-formylbenzenesulfonate dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4-formylbenzenesulfonate:NAD+ oxidoreductase
Reaction(IUBMB)
4-formylbenzenesulfonate + NAD+ + H2O = 4-sulfobenzoate + NADH + 2 H+ [RN:R05272]
Reaction(KEGG)
R05272
Substrate
4-formylbenzenesulfonate [CPD:C06679];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-sulfobenzoate [CPD:C02236];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the toluene-4-sulfonate degradation pathway.
History
EC 1.2.1.62 created 2000
Pathway
ec00623  Toluene degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K19630  4-formylbenzenesulfonate dehydrogenase
Reference
1  [PMID:8828208]
  Authors
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM
  Title
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.
  Journal
Microbiology 142 ( Pt 9):2419-27 (1996)
DOI:10.1099/00221287-142-9-2419
  Sequence
[ag:AAC44807]
Reference
2  [PMID:9006050]
  Authors
Junker F, Kiewitz R, Cook AM
  Title
Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2.
  Journal
J Bacteriol 179:919-27 (1997)
DOI:10.1128/JB.179.3.919-927.1997
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.62
IUBMB Enzyme Nomenclature: 1.2.1.62
ExPASy - ENZYME nomenclature database: 1.2.1.62
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.62
BRENDA, the Enzyme Database: 1.2.1.62
CAS: 167973-68-4
LinkDB

KEGG   REACTION: R05272
Entry
R05272                      Reaction                               
Name
4-formylbenzenesulfonate:NAD+ oxidoreductase
Definition
4-Sulfobenzaldehyde + NAD+ + H2O <=> 4-Sulfobenzoate + NADH + H+
Equation
C06679 + C00003 + C00001 <=> C02236 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00075  C02236_C06679
Enzyme
1.2.1.62
Pathway
rn00623  Toluene degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.62
     R05272  4-Sulfobenzaldehyde + NAD+ + H2O <=> 4-Sulfobenzoate + NADH + H+
Orthology
K19630  4-formylbenzenesulfonate dehydrogenase [EC:1.2.1.62]
Other DBs
RHEA: 18836
LinkDB

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