KEGG   ORTHOLOGY: K19670
Entry
K19670                      KO                                     
Symbol
phnA
Name
phosphonoacetate hydrolase [EC:3.11.1.2]
Pathway
map00440  Phosphonate and phosphinate metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K19670  phnA; phosphonoacetate hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.11  Acting on carbon-phosphorus bonds
   3.11.1  Acting on carbon-phosphorus bonds (only sub-subclass identified to date)
    3.11.1.2  phosphonoacetate hydrolase
     K19670  phnA; phosphonoacetate hydrolase
Other DBs
RN: R00318
COG: COG1524
GO: 0047400
Genes
SPIS: 111345410
SOD: Sant_0055
LGU: LG3211_2563(phnA)
AVN: Avin_17500
AVL: AvCA_17500
AVD: AvCA6_17500
MARS: A8C75_10790
REH: H16_B0836(phnA) H16_B1948(h16_B1948)
CNC: CNE_2c07990(phnA1) CNE_2c19110(phnA2)
CUH: BJN34_32285
CGD: CR3_4144
COX: E0W60_03290(phnA)
BMA: BMAA0859(phnA)
BMV: BMASAVP1_1762(phnA)
BML: BMA10229_2214(phnA)
BMN: BMA10247_A0900(phnA)
BMAE: DM78_3993(phnA)
BMAI: DM57_09860
BMAF: DM51_4553(phnA)
BMAZ: BM44_4873(phnA)
BMAB: BM45_3775(phnA)
BPS: BPSS0348
BPM: BURPS1710b_A1904(phnA)
BPL: BURPS1106A_A0491(phnA)
BPD: BURPS668_A0588(phnA)
BPSE: BDL_3580(phnA)
BPSM: BBQ_5851(phnA)
BPSU: BBN_3744(phnA)
BPSD: BBX_5418(phnA)
BPK: BBK_5560(phnA)
BPSH: DR55_4999(phnA)
BPSA: BBU_5769(phnA)
BPSO: X996_4768(phnA)
BUT: X994_4268(phnA)
BTE: BTH_II2050(phnA-2)
BTQ: BTQ_5330(phnA)
BTJ: BTJ_3982(phnA)
BTZ: BTL_4806(phnA)
BTD: BTI_4382(phnA)
BTV: BTHA_5424(phnA)
BTHE: BTN_4456(phnA)
BTHM: BTRA_4721(phnA)
BTHA: DR62_4570
BTHL: BG87_4787(phnA)
BOK: DM82_4423(phnA)
BOC: BG90_6147(phnA)
BSAV: WS86_20580
BVE: AK36_3215(phnA)
BCJ: BCAL0450 BCAM2494(phnA)
BCEN: DM39_3244(phnA) DM39_5343(phnA)
BCEW: DM40_3146(phnA)
BCEO: I35_3215 I35_6394(phnA)
BMK: DM80_1720(phnA) DM80_4810(phnA)
BMUL: NP80_114(phnA) NP80_5122(phnA)
BCED: DM42_1816(phnA) DM42_5480(phnA)
BDL: AK34_3335(phnA)
BUB: BW23_1740(phnA) BW23_3715(phnA)
BLAT: WK25_28320
BANN: JFN94_16085(phnA) JFN94_16835(phnA)
BGU: KS03_5526(phnA)
BGO: BM43_4195(phnA) BM43_444(phnA)
BUK: MYA_3171
BUL: BW21_3915(phnA)
BGP: BGL_2c04860(phnA)
BURK: DM992_04075(phnA) DM992_24155(phnA)
BXE: Bxe_B1870
BXB: DR64_7180(phnA)
BPH: Bphy_5070
BFN: OI25_4328(phnA) OI25_4864(phnA)
PSPW: BJG93_17435(phnA)
PARB: CJU94_20355(phnA)
PHS: C2L64_27730(phnA) C2L64_33580(phnA)
PTER: C2L65_20770(phnA) C2L65_30160(phnA)
PGP: CUJ91_07045(phnA) CUJ91_26155(phnA)
PCJ: CUJ87_19130(phnA)
PTS: CUJ90_19165(phnA)
PMEG: FNZ07_09305(phnA)
PEW: KZJ38_30325(phnA) KZJ38_33540(phnA)
PDIO: PDMSB3_1180.1(phnA) PDMSB3_3466(phnA)
PPNO: DA70_13415
PPNM: LV28_17285
PPUL: RO07_11410
PSPU: NA29_07230
PAPI: SG18_11790
PAND: DRB87_02880(phnA)
PFIB: PI93_002835(phnA)
PLG: NCTC10937_03430(phnA)
CABA: SBC2_67570(phnA_1) SBC2_80210(phnA_2)
BPAR: BN117_3778(phnA)
BBH: BN112_2433(phnA)
BBR: BB1010(phnA)
BBM: BN115_0965(phnA)
BBX: BBS798_0984(phnA)
AAQU: D3M96_18740(phnA)
BOZ: DBV39_15360(phnA)
PIG: EGT29_11350(phnA)
RHG: EXZ61_00860(phnA)
POS: DT070_07560(phnA)
POO: F7R28_01860(phnA)
VEI: Veis_1096
VBO: CKY39_09870(phnA) CKY39_30080(phnA)
VAM: C4F17_27625(phnA) C4F17_29370(phnA)
LIM: L103DPR2_01228(phnA)
DIH: G7047_26105(phnA)
DRG: H9K76_21720(phnA)
HEE: hmeg3_09350(phnA)
CFU: CFU_0637(phnA)
CARE: LT85_0694
CPRA: CPter91_0748(phnA) CPter91_4526(phnA)
SWS: I6J16_03765(phnA)
URU: DSM104443_01235(phnA)
UPL: DSM104440_01165(phnA)
MESP: C1M53_19320(phnA)
MERD: EB233_26580(phnA)
MESR: FGU64_08325(phnA)
AMIH: CO731_05468(phnA)
SME: SM_b21538(phnA)
SMI: BN406_05686(phnA)
SMEL: SM2011_b21538(phnA)
SMER: DU99_28545
SMD: Smed_4875
SIX: BSY16_5628(phnA)
EMX: FKV68_16760(phnA)
AVI: Avi_9252
PSCQ: KHQ08_12900(phnA)
AOL: S58_09400
BRK: CWS35_18315(phnA) CWS35_21300(phnA)
BQB: J4P68_0002465(phnA)
RPA: RPA3737
RPC: RPC_2339
RPT: Rpal_4258
OCA: OCAR_6851(phnA)
BOS: BSY19_940
STAR: G3545_02510(phnA)
APRA: G3A50_07905(phnA)
DEA: FPZ08_14935(phnA)
AALM: LUX29_13235(phnA)
NOH: G5V57_22795(phnA)
PSTG: E8M01_18205(phnA) E8M01_19125(phnA) E8M01_31375(phnA)
ACUT: MRB58_08750(phnA)
RUA: D1823_18760(phnA)
RUT: FIU92_18145(phnA)
LAQU: R2C4_02150(phnA)
SULI: C1J05_07705(phnA)
ROM: EI983_15765(phnA)
PZH: CX676_16685(phnA)
PLIA: E4191_05970(phnA)
SEDI: EBB79_05345(phnA)
PAED: G5B38_01295(phnA) G5B38_14160(phnA)
THAS: C6Y53_07950(phnA)
SMAZ: LH19_15825
SHUM: STHU_12460
SVC: STVA_36690(phnA)
STEL: STAQ_37220
HTQ: FRZ44_32160(phnA)
HADH: FRZ61_15490(phnA)
CBE: Cbei_3507
CBZ: Cbs_3507
CBEI: LF65_03952
MMAT: MMAGJ_34320(phnA)
RHS: A3Q41_02879(phnA)
SALU: DC74_7218
SALL: SAZ_37420
SXN: IAG42_18295(phnA)
SAIU: J4H86_07150(phnA)
FAL: FRAAL6035
TRO: trd_1148
LUO: HHL09_10175(phnA)
LAMB: KBB96_15735(phnA)
SDYN: Mal52_16190(phnA)
SUS: Acid_4377
FLC: KJS93_18185(phnA)
PGS: CPT03_11840(phnA)
AALG: AREALGSMS7_02093(phnA)
AG: AAC15507(phnA)
 » show all
Reference
PMID:8529644
  Authors
McGrath JW, Wisdom GB, McMullan G, Larkin MJ, Quinn JP
  Title
The purification and properties of phosphonoacetate hydrolase, a novel carbon-phosphorus bond-cleavage enzyme from Pseudomonas fluorescens 23F.
  Journal
Eur J Biochem 234:225-30 (1995)
DOI:10.1111/j.1432-1033.1995.225_c.x
  Sequence
LinkDB

KEGG   ENZYME: 3.11.1.2
Entry
EC 3.11.1.2                 Enzyme                                 
Name
phosphonoacetate hydrolase
Class
Hydrolases;
Acting on carbon-phosphorus bonds;
Acting on carbon-phosphorus bonds (only sub-subclass identified to date)
Sysname
phosphonoacetate phosphonohydrolase
Reaction(IUBMB)
phosphonoacetate + H2O = acetate + phosphate [RN:R00318]
Reaction(KEGG)
R00318
Substrate
phosphonoacetate [CPD:C05682];
H2O [CPD:C00001]
Product
acetate [CPD:C00033];
phosphate [CPD:C00009]
Comment
A zinc-dependent enzyme. Belongs to the alkaline phosphatase superfamily of zinc-dependent hydrolases.
History
EC 3.11.1.2 created 1999
Pathway
ec00440  Phosphonate and phosphinate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K19670  phosphonoacetate hydrolase
Genes
SPIS111345410
SODSant_0055
LGULG3211_2563(phnA)
AVNAvin_17500
AVLAvCA_17500
AVDAvCA6_17500
MARSA8C75_10790
REHH16_B0836(phnA) H16_B1948(h16_B1948)
CNCCNE_2c07990(phnA1) CNE_2c19110(phnA2)
CUHBJN34_32285
REUReut_B3720 Reut_B5876
CTIRALTA_B0698(phnA) RALTA_B1649
CGDCR3_4144
COXE0W60_03290(phnA)
BMABMAA0859(phnA)
BMVBMASAVP1_1762(phnA)
BMLBMA10229_2214(phnA)
BMNBMA10247_A0900(phnA)
BMAEDM78_3993(phnA)
BMAIDM57_09860
BMAFDM51_4553(phnA)
BMAZBM44_4873(phnA)
BMABBM45_3775(phnA)
BPSBPSS0348
BPMBURPS1710b_A1904(phnA)
BPLBURPS1106A_A0491(phnA)
BPDBURPS668_A0588(phnA)
BPSEBDL_3580(phnA)
BPSMBBQ_5851(phnA)
BPSUBBN_3744(phnA)
BPSDBBX_5418(phnA)
BPZBP1026B_II0378
BPQBPC006_II0468
BPKBBK_5560(phnA)
BPSHDR55_4999(phnA)
BPSABBU_5769(phnA)
BPSOX996_4768(phnA)
BUTX994_4268(phnA)
BTEBTH_II2050(phnA-2)
BTQBTQ_5330(phnA)
BTJBTJ_3982(phnA)
BTZBTL_4806(phnA)
BTDBTI_4382(phnA)
BTVBTHA_5424(phnA)
BTHEBTN_4456(phnA)
BTHMBTRA_4721(phnA)
BTHADR62_4570
BTHLBG87_4787(phnA)
BOKDM82_4423(phnA)
BOCBG90_6147(phnA)
BUUWS70_19235
BSAVWS86_20580
BVIBcep1808_3544
BVEAK36_3215(phnA)
BURBcep18194_A6493 Bcep18194_B0352
BCNBcen_2529 Bcen_3071
BCHBcen2424_3142 Bcen2424_5296
BCMBcenmc03_3158 Bcenmc03_4972
BCJBCAL0450 BCAM2494(phnA)
BCENDM39_3244(phnA) DM39_5343(phnA)
BCEWDM40_3146(phnA)
BCEOI35_3215 I35_6394(phnA)
BAMBamb_3194 Bamb_4657
BACBamMC406_3077 BamMC406_5185
BMJBMULJ_00095
BMUBmul_3134 Bmul_3427
BMKDM80_1720(phnA) DM80_4810(phnA)
BMULNP80_114(phnA) NP80_5122(phnA)
BCTGEM_0290 GEM_5901
BCEDDM42_1816(phnA) DM42_5480(phnA)
BCEPAPZ15_03720 APZ15_23025
BDLAK34_3335(phnA)
BPYRABD05_05795 ABD05_23085
BCONNL30_16300 NL30_28870
BUBBW23_1740(phnA) BW23_3715(phnA)
BDFWI26_15225 WI26_25290
BLATWK25_28320
BTEIWS51_09425 WS51_26120
BSEMWJ12_15750 WJ12_32530
BPSLWS57_01645 WS57_34550
BMECWJ16_15940 WJ16_31005
BSTGWT74_16575 WT74_31355
BSTLBBJ41_12775 BBJ41_26450
BANNJFN94_16085(phnA) JFN94_16835(phnA)
BGLbglu_2g03940
BGUKS03_5526(phnA)
BUGBC1001_5539
BGDbgla_2g05650
BGOBM43_4195(phnA) BM43_444(phnA)
BYIBYI23_D005240
BUKMYA_3171
BUEBRPE67_DCDS07040
BULBW21_3915(phnA)
BUQAC233_30045
BGPBGL_2c04860(phnA)
BPLAbpln_2g05410
BUDAQ610_21330
BUMAXG89_18175
BUIAX768_20705 AX768_27950
BURKDM992_04075(phnA) DM992_24155(phnA)
BXEBxe_B1870
BXBDR64_7180(phnA)
BPHBphy_5070
BGEBC1002_3628 BC1002_6646
BPXBUPH_05554
BPYBphyt_4794
BUZAYM40_24085
BFNOI25_4328(phnA) OI25_4864(phnA)
BCAIK788_0006027 K788_0008336
PSPWBJG93_17435(phnA)
PARABTO02_27725
PARBCJU94_20355(phnA)
PHSC2L64_27730(phnA) C2L64_33580(phnA)
PTERC2L65_20770(phnA) C2L65_30160(phnA)
PGPCUJ91_07045(phnA) CUJ91_26155(phnA)
PCJCUJ87_19130(phnA)
PTSCUJ90_19165(phnA)
PCAFDSC91_001813
PMEGFNZ07_09305(phnA)
PEWKZJ38_30325(phnA) KZJ38_33540(phnA)
PDIOPDMSB3_1180.1(phnA) PDMSB3_3466(phnA)
PPKU875_20725
PPNODA70_13415
PPNMLV28_17285
PRBX636_13450
PPULRO07_11410
PSPUNA29_07230
PAPISG18_11790
PVEUC34_03105
POXMB84_07605
PTXABW99_14195
PFGAB870_14320
PNRAT302_11255
PANDDRB87_02880(phnA)
PFIBPI93_002835(phnA)
PLGNCTC10937_03430(phnA)
CABASBC2_67570(phnA_1) SBC2_80210(phnA_2)
BUOBRPE64_CCDS06620
BPARBN117_3778(phnA)
BBHBN112_2433(phnA)
BBRBB1010(phnA)
BBMBN115_0965(phnA)
BBXBBS798_0984(phnA)
AAQUD3M96_18740(phnA)
BOZDBV39_15360(phnA)
PIGEGT29_11350(phnA)
RHGEXZ61_00860(phnA)
POLBpro_3220 Bpro_4692
POSDT070_07560(phnA)
POOF7R28_01860(phnA)
VEIVeis_1096
VPEVarpa_1737 Varpa_2142
VBOCKY39_09870(phnA) CKY39_30080(phnA)
VAMC4F17_27625(phnA) C4F17_29370(phnA)
ADNAlide_4219
ADKAlide2_4560
LIML103DPR2_01228(phnA)
DIHG7047_26105(phnA)
DRGH9K76_21720(phnA)
HEEhmeg3_09350(phnA)
CFUCFU_0637(phnA)
CARELT85_0694
CPRACPter91_0748(phnA) CPter91_4526(phnA)
SWSI6J16_03765(phnA)
URUDSM104443_01235(phnA)
UPLDSM104440_01165(phnA)
BEBABWI17_20735
SCUSCE1572_15275
MRMA7982_05269
MCIMesci_5290
MOPMesop_5913
MAMMesau_05387
MESWA9K65_028935
MESPC1M53_19320(phnA)
MERDEB233_26580(phnA)
MESRFGU64_08325(phnA)
HOEIMCC20628_02178
AAKAA2016_5848
AMIHCO731_05468(phnA)
PHTBLM14_26045
SMESM_b21538(phnA)
SMKSinme_4733
SMQSinmeB_3692
SMXSM11_pD0622
SMIBN406_05686(phnA)
SMEGC770_GR4pD0607
SMELSM2011_b21538(phnA)
SMERDU99_28545
SMDSmed_4875
SIXBSY16_5628(phnA)
EAHFA04_31245
EMXFKV68_16760(phnA)
AVIAvi_9252
SHZshn_14570 shn_17315
PSCQKHQ08_12900(phnA)
AOLS58_09400
BRKCWS35_18315(phnA) CWS35_21300(phnA)
BELBE61_49280
BQBJ4P68_0002465(phnA)
RPARPA3737
RPCRPC_2339
RPTRpal_4258
OCAOCAR_6851(phnA)
OCGOCA5_c12270
OCOOCA4_c12270
BOPAXW83_08860
BOSBSY19_940
BVVBHK69_06145
BOIBLM15_05125 BLM15_17275
BOFFQV39_06790
STARG3545_02510(phnA)
APRAG3A50_07905(phnA)
CHELAL346_10075
DEAFPZ08_14935(phnA)
AALMLUX29_13235(phnA)
PSINCAK95_11570
NOHG5V57_22795(phnA)
PSTGE8M01_18205(phnA) E8M01_19125(phnA) E8M01_31375(phnA)
ACUTMRB58_08750(phnA)
RUAD1823_18760(phnA)
RUTFIU92_18145(phnA)
LMDMETH_22745
LAQUR2C4_02150(phnA)
SULIC1J05_07705(phnA)
ROMEI983_15765(phnA)
HATRC74_13420
PZHCX676_16685(phnA)
PLIAE4191_05970(phnA)
DAAAKL17_3749
SEDIEBB79_05345(phnA)
PAEDG5B38_01295(phnA) G5B38_14160(phnA)
THASC6Y53_07950(phnA)
SMAGAN936_06190
SMAZLH19_15825
SPHXE5675_16840
SHUMSTHU_12460
SVCSTVA_36690(phnA)
STELSTAQ_37220
HTQFRZ44_32160(phnA)
HADHFRZ61_15490(phnA)
PELSAR11G3_00179
APCHIMB59_00004470
BBADK7T73_09505
CBECbei_3507
CBZCbs_3507
CBEILF65_03952
CDYF3K33_17780
PEDING2D1G_1557
MEGDKB62_09155
MGOAFA91_28195
MLLB1R94_12005
MMATMMAGJ_34320(phnA)
RHSA3Q41_02879(phnA)
RHWBFN03_00275 BFN03_19650
DITC3V38_14300
DPCA6048_08745
DLUA6035_08305
SALUDC74_7218
SALLSAZ_37420
SVTSVTN_38865
SXNIAG42_18295(phnA)
ARYATC04_16335
LMOIVV02_16600 VV02_16745
NOYEXE57_08285
SAIUJ4H86_07150(phnA)
FREFranean1_0937
FRIFraEuI1c_0768
FALFRAAL6035
FSYFsymDg_0922
TROtrd_1148
KBSEPA93_07555
LUOHHL09_10175(phnA)
LAMBKBB96_15735(phnA)
SDYNMal52_16190(phnA)
GMSSOIL9_67960
SUSAcid_4377
FLCKJS93_18185(phnA)
PCMAY601_2826
PSTYBFS30_02930
PGSCPT03_11840(phnA)
MUHHYN43_024620
MGKFSB76_03615
MRUBDEO27_027060
SBXCA265_07365
FPSZAMR72_12790
AALGAREALGSMS7_02093(phnA)
HALXM0R89_21275
 » show all
Reference
1  [PMID:8529644]
  Authors
McGrath JW, Wisdom GB, McMullan G, Larkin MJ, Quinn JP
  Title
The purification and properties of phosphonoacetate hydrolase, a novel carbon-phosphorus bond-cleavage enzyme from Pseudomonas fluorescens 23F.
  Journal
Eur J Biochem 234:225-30 (1995)
DOI:10.1111/j.1432-1033.1995.225_c.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.11.1.2
IUBMB Enzyme Nomenclature: 3.11.1.2
ExPASy - ENZYME nomenclature database: 3.11.1.2
BRENDA, the Enzyme Database: 3.11.1.2
CAS: 153570-68-4
LinkDB

KEGG   REACTION: R00318
Entry
R00318                      Reaction                               
Name
Phosphonoacetate phosphonohydrolase
Definition
Phosphonoacetate + H2O <=> Acetate + Orthophosphate
Equation
Reaction class
RC01309  C00033_C05682
Enzyme
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K19670  phosphonoacetate hydrolase [EC:3.11.1.2]
Other DBs
RHEA: 16752
LinkDB

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