KEGG   ORTHOLOGY: K19744
Entry
K19744                      KO                                     
Symbol
dauB
Name
L-arginine dehydrogenase [EC:1.4.1.25]
Pathway
map00470  D-Amino acid metabolism
map01100  Metabolic pathways
Module
M00947  D-Arginine racemization, D-arginine => L-arginine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K19744  dauB; L-arginine dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.25  L-arginine dehydrogenase
     K19744  dauB; L-arginine dehydrogenase
Other DBs
RN: R11031 R11032
COG: COG2423
Genes
PALH: B1H58_18955
PPR: PBPRB0030(PA3862)
PAE: PA3862(dauB)
PAEV: N297_3988
PAEI: N296_3988
PAU: PA14_14020
PAP: PSPA7_1243
PAG: PLES_11121
PAF: PAM18_1076
PNC: NCGM2_5052
PAEP: PA1S_05510
PAEM: U769_05545
PAEL: T223_05460
PAEG: AI22_28105
PAEC: M802_3986
PAEO: M801_3854
PMY: Pmen_3566
PFL: PFL_1045
PPRO: PPC_1082
PFB: VO64_5502
PMAN: OU5_2435
PKC: PKB_0989
PSEM: TO66_05260
PSOS: POS17_1042
PANR: A7J50_2221
PSET: THL1_1153
PSIL: PMA3_04250
POJ: PtoMrB4_46060(dauB)
PSEP: C4K39_1054
PTW: TUM18999_49970(dauB)
BCN: Bcen_0365
BCJ: BCAL3157
BCEN: DM39_657
BCEW: DM40_1511
BCEO: I35_0706
BAM: Bamb_0723
BMU: Bmul_2539
BMK: DM80_839
BMUL: NP80_860
BCT: GEM_2683
BCED: DM42_982
BDL: AK34_2328
BCON: NL30_11560
BLAT: WK25_03945
BTEI: WS51_14505
BSEM: WJ12_03835
BPSL: WS57_21640
BMEC: WJ16_03870
BSTG: WT74_04145
BPH: Bphy_3431
BFN: OI25_6281
SHZ: shn_32355
SMAZ: LH19_04515
SECH: B18_02355
STRE: GZL_01015
 » show all
Reference
  Authors
Li C, Lu CD
  Title
Arginine racemization by coupled catabolic and anabolic dehydrogenases.
  Journal
Proc Natl Acad Sci U S A 106:906-11 (2009)
DOI:10.1073/pnas.0808269106
  Sequence
[pae:PA3862]
LinkDB

KEGG   ENZYME: 1.4.1.25
Entry
EC 1.4.1.25                 Enzyme                                 
Name
L-arginine dehydrogenase;
dauB (gene name);
anabolic L-arginine dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-arginine:NAD(P)+ oxidoreductase (deaminating)
Reaction(IUBMB)
L-arginine + H2O + NAD(P)+ = 5-guanidino-2-oxopentanoate + NH3 + NAD(P)H + H+ [RN:R11031 R11032]
Reaction(KEGG)
R11031 R11032
Substrate
L-arginine [CPD:C00062];
H2O [CPD:C00001];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
5-guanidino-2-oxopentanoate [CPD:C03771];
NH3 [CPD:C00014];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, which has been isolated from the bacterium Pseudomonas aeruginosa PAO1, forms with EC 1.4.99.6, D-arginine dehydrogenase, a two-enzyme complex involved in the racemization of D- and L-arginine.
History
EC 1.4.1.25 created 2017
Pathway
ec00470  D-Amino acid metabolism
ec01100  Metabolic pathways
Orthology
K19744  L-arginine dehydrogenase
Genes
PALHB1H58_18955
PPRPBPRB0030(PA3862)
PAEPA3862(dauB)
PAEVN297_3988
PAEIN296_3988
PAUPA14_14020
PAPPSPA7_1243
PAGPLES_11121
PAFPAM18_1076
PNCNCGM2_5052
PAEBNCGM1900_1111
PDKPADK2_05005
PSGG655_05385
PRPM062_20420
PAEPPA1S_05510
PAERPA1R_gp1756
PAEMU769_05545
PAELT223_05460
PAESSCV20265_1135
PAEUBN889_04293
PAEGAI22_28105
PAECM802_3986
PAEOM801_3854
PMYPmen_3566
PREPCA10_11000
PFUWKF707C_10270
PALCA0T30_06955
PMUIG4G71_09100
PFLPFL_1045
PPRCPFLCHA0_c10640
PPROPPC_1082
PFEPSF113_4742
PFOPfl01_0970
PFCPflA506_2228
PFBVO64_5502
PMANOU5_2435
PTVAA957_03145
PCGAXG94_09920
PVRPverR02_12350
PAZOAYR47_18380
PRXHRH33_11185
PFWPF1751_v1c20450
PFFPFLUOLIPICF726490
PFXA7318_09935
PBAPSEBR_a4580
PBCCD58_24250
PPUUPputUW4_04461
PDRH681_19275
PSKU771_12280
PKCPKB_0989
PCHEY04_04570
PCZPCL1606_50590
PCPJM49_25075
PALKPSAKL28_08840
PSEMTO66_05260
PSOSPOS17_1042
PKRAYO71_07590
PFKPFAS1_16745
PANRA7J50_2221
PSETTHL1_1153
PSILPMA3_04250
PKEDLD99_05210
PUMHGP31_04845
POJPtoMrB4_46060(dauB)
PGYAWU82_19030 AWU82_29060
PLALFXN65_05125
PVKEPZ47_24275
PBZGN234_24070
PATAJWU58_22700
PDWBV82_4677C
PZEHU754_006325
PMOEHV782_005900
PCAMHNE05_02895
PSEPC4K39_1054
PVWHU752_020810
PTRTHU722_0011760
PSAMHU731_027915
PTZHU718_005960
PQIKH389_22200
PHVHU739_012660
PPRGHU725_013415
PAZEKSS91_23795
PALVKSS97_06345
PORYEJA05_04850
PTKEXN22_22875
PTWTUM18999_49970(dauB)
PZAHU749_024085
PIEHU724_005725
ORBIPMB12_01150
VOGLCH97_01975
BURBcep18194_A3938
BCNBcen_0365
BCHBcen2424_0848
BCMBcenmc03_0820
BCJBCAL3157
BCENDM39_657
BCEWDM40_1511
BCEOI35_0706
BAMBamb_0723
BACBamMC406_0740
BMJBMULJ_00699
BMUBmul_2539
BMKDM80_839
BMULNP80_860
BCTGEM_2683
BCEDDM42_982
BCEPAPZ15_07875
BDLAK34_2328
BPYRABD05_09845
BCONNL30_11560
BDFWI26_03730
BLATWK25_03945
BTEIWS51_14505
BSEMWJ12_03835
BPSLWS57_21640
BMECWJ16_03870
BSTGWT74_04145
BSTLBBJ41_07940
BANNJFN94_04020
BUGBC1001_3931
BYIBYI23_C013410
BUEBRPE67_CCDS13080
BUQAC233_21940
BURKDM992_17370
BPHBphy_3431
BGEBC1002_4530
BPXBUPH_00515
BPYBphyt_2072
BUZAYM40_32340
BFNOI25_6281
BCAIK788_0007543
PHSC2L64_22690
PTERC2L65_24905
PGPCUJ91_21585
PCJCUJ87_22380
PTSCUJ90_24110
PCAFDSC91_002143
PTROG5S35_15200
EADOV14_b1239
EAHFA04_28125
RELREMIM1_PC00033
SHZshn_32355
ABAWD5400_18045
MOCBB934_32250
CAULKCG34_07640
SULZC1J03_09690
SEDIEBB79_04115
SMAGAN936_14040
SMAZLH19_04515
SECHB18_02355
STREGZL_01015
MCRAID554_30815
 » show all
Reference
1  [PMID:19139398]
  Authors
Li C, Lu CD
  Title
Arginine racemization by coupled catabolic and anabolic dehydrogenases.
  Journal
Proc Natl Acad Sci U S A 106:906-11 (2009)
DOI:10.1073/pnas.0808269106
  Sequence
[pae:PA3862]
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.25
IUBMB Enzyme Nomenclature: 1.4.1.25
ExPASy - ENZYME nomenclature database: 1.4.1.25
BRENDA, the Enzyme Database: 1.4.1.25
LinkDB

KEGG   REACTION: R11031
Entry
R11031                      Reaction                               
Name
L-arginine:NAD+ oxidoreductase (deaminating)
Definition
5-Guanidino-2-oxopentanoate + NADH + H+ + Ammonia <=> L-Arginine + NAD+ + H2O
Equation
Comment
L-arginine dehydrogenase
Reaction class
RC00001  C00003_C00004
RC00006  C00062_C03771
Enzyme
Pathway
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
Module
M00947  D-Arginine racemization, D-arginine => L-arginine
Orthology
K19744  L-arginine dehydrogenase [EC:1.4.1.25]
Other DBs
RHEA: 47635
LinkDB

KEGG   REACTION: R11032
Entry
R11032                      Reaction                               
Name
L-arginine:NADP+ oxidoreductase (deaminating)
Definition
5-Guanidino-2-oxopentanoate + NADPH + H+ + Ammonia <=> L-Arginine + NADP+ + H2O
Equation
Comment
L-arginine dehydrogenase
Reaction class
RC00001  C00005_C00006
RC00006  C00062_C03771
Enzyme
Pathway
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
Module
M00947  D-Arginine racemization, D-arginine => L-arginine
Orthology
K19744  L-arginine dehydrogenase [EC:1.4.1.25]
Other DBs
RHEA: 47639
LinkDB

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