KEGG   ORTHOLOGY: K19979
Entry
K19979                      KO                                     
Symbol
acbM
Name
2-epi-5-epi-valiolone 7-kinase [EC:2.7.1.188]
Pathway
map00525  Acarbose and validamycin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00814  Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00525 Acarbose and validamycin biosynthesis
    K19979  acbM; 2-epi-5-epi-valiolone 7-kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.188  2-epi-5-epi-valiolone 7-kinase
     K19979  acbM; 2-epi-5-epi-valiolone 7-kinase
Other DBs
RN: R11185
COG: COG1940
Genes
SERA: Ser39006_003955
SERQ: CWC46_03955
PEZ: HWQ56_09185
CVC: BKX93_19950
AVM: JQX13_08235
MUL: MUL_0546
MMI: MMAR_0581
MMAE: MMARE11_05380
NSR: NS506_05936
NAH: F5544_18750
RER: RER_54460
REY: O5Y_25935
RHB: NY08_86
RHS: A3Q41_04756(nanK_2)
SALS: SLNWT_0590
SRW: TUE45_05036(glcK)
SLE: sle_45860(sle_45860)
SAUH: SU9_022205
SESP: BN6_52650
ACTI: UA75_21505
ACAD: UA74_21025
ASE: ACPL_3676(acbM) ACPL_6249
 » show all
Reference
  Authors
Zhang CS, Stratmann A, Block O, Bruckner R, Podeschwa M, Altenbach HJ, Wehmeier UF, Piepersberg W
  Title
Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway.
  Journal
J Biol Chem 277:22853-62 (2002)
DOI:10.1074/jbc.M202375200
  Sequence
[ase:ACPL_3676]
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