KEGG   ORTHOLOGY: K20678
Entry
K20678            Tight     KO                                     
Symbol
fcf2
Name
dTDP-fucopyranose mutase [EC:5.4.99.59]
Pathway
map00523  Polyketide sugar unit biosynthesis
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K20678  fcf2; dTDP-fucopyranose mutase
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K20678  fcf2; dTDP-fucopyranose mutase
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.59  dTDP-fucopyranose mutase
     K20678  fcf2; dTDP-fucopyranose mutase
Other DBs
RN: R10536
COG: COG0562
Genes
AG: AAS99162(fcf2)
Reference
  Authors
Wang Q, Ding P, Perepelov AV, Xu Y, Wang Y, Knirel YA, Wang L, Feng L
  Title
Characterization of the dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52.
  Journal
Mol Microbiol 70:1358-67 (2008)
DOI:10.1111/j.1365-2958.2008.06449.x
  Sequence
LinkDB

KEGG   ENZYME: 5.4.99.59
Entry
EC 5.4.99.59                Enzyme                                 
Name
dTDP-fucopyranose mutase;
Fcf2
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
dTDP-alpha-D-fucopyranose furanomutase
Reaction(IUBMB)
dTDP-alpha-D-fucopyranose = dTDP-alpha-D-fucofuranose [RN:R10536]
Reaction(KEGG)
R10536
Substrate
dTDP-alpha-D-fucopyranose [CPD:C07277]
Product
dTDP-alpha-D-fucofuranose [CPD:C20682]
Comment
The enzyme is involved in the biosynthesis of the Escherichia coli O52 O antigen.
History
EC 5.4.99.59 created 2013
Pathway
ec00523  Polyketide sugar unit biosynthesis
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K20678  dTDP-fucopyranose mutase
Reference
1  [PMID:19019146]
  Authors
Wang Q, Ding P, Perepelov AV, Xu Y, Wang Y, Knirel YA, Wang L, Feng L
  Title
Characterization of the dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52.
  Journal
Mol Microbiol 70:1358-67 (2008)
DOI:10.1111/j.1365-2958.2008.06449.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.59
IUBMB Enzyme Nomenclature: 5.4.99.59
ExPASy - ENZYME nomenclature database: 5.4.99.59
BRENDA, the Enzyme Database: 5.4.99.59
LinkDB

KEGG   REACTION: R10536
Entry
R10536                      Reaction                               
Name
dTDP-alpha-D-fucopyranose furanomutase
Definition
dTDP-D-fucose <=> dTDP-alpha-D-fucofuranose
Equation
Reaction class
RC00317  C07277_C20682
Enzyme
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Orthology
K20678  dTDP-fucopyranose mutase [EC:5.4.99.59]
Other DBs
RHEA: 36818
LinkDB

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