KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
K21146 CYP105A1; vitamin D 1,25-hydroxylase
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450
K21146 CYP105A1; vitamin D 1,25-hydroxylase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15.22 vitamin D 1,25-hydroxylase
K21146 CYP105A1; vitamin D 1,25-hydroxylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, bacteria type
CYP105 family
K21146 CYP105A1; vitamin D 1,25-hydroxylase
vitamin D 1,25-hydroxylase;
CYP105A1;
Streptomyces griseolus cytochrome P450SU-1
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
A P-450 (heme-thiolate) enzyme found in the bacterium Streptomyces griseolus. cf. EC 1.14.14.24, vitamin D 25-hydroxylase and EC 1.14.15.18, calcidiol 1-monooxygenase.
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15.22
R11459 Calcidiol + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Calcitriol + 2 Oxidized ferredoxin + H2O