KEGG   ORTHOLOGY: K21208
Entry
K21208            Tight     KO                                     
Symbol
CYP96T1
Name
noroxomaritidine synthase [EC:1.14.19.50 1.14.19.-]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R08440  
R11482  4'-O-methylnorbelladine,NADPH---hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming)
R11483  4'-O-methylnorbelladine,NADPH---hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K21208  CYP96T1; noroxomaritidine synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K21208  CYP96T1; noroxomaritidine synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.50  noroxomaritidine synthase
     K21208  CYP96T1; noroxomaritidine synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP96 family
   K21208  CYP96T1; noroxomaritidine synthase
Genes
AG: AMO65741(CYP96T1)
Reference
PMID:26941773
  Authors
Kilgore MB, Augustin MM, May GD, Crow JA, Kutchan TM
  Title
CYP96T1 of Narcissus sp. aff. pseudonarcissus Catalyzes Formation of the Para-Para' C-C Phenol Couple in the Amaryllidaceae Alkaloids.
  Journal
Front Plant Sci 7:225 (2016)
DOI:10.3389/fpls.2016.00225
  Sequence
[ag:AMO65741]
LinkDB

KEGG   REACTION: R08440
Entry
R08440                      Reaction                               
Definition
4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Demethylnarwedine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C16702 + C03024 + C00007 <=> C16703 + C03161 + 2 C00001
Reaction class
RC02283  C16702_C16703
Enzyme
1.14.19.-
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.-
     R08440  4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Demethylnarwedine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Orthology
K21208  noroxomaritidine synthase [EC:1.14.19.50 1.14.19.-]
LinkDB

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