KEGG   ORTHOLOGY: K21221
Entry
K21221            Tight     KO                                     
Symbol
kedU38
Name
iterative type I polyketide synthase KedU38
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
Module
M00831  Kedarcidin 2-hydroxynaphthoate moiety biosynthesis, malonyl-CoA => 3,6,8-trihydroxy-2-naphthoate => 3-hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21221  kedU38; iterative type I polyketide synthase KedU38
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21221  kedU38; iterative type I polyketide synthase KedU38
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Iterative type I PKS
   Bacterial type
    K21221  kedU38; iterative type I polyketide synthase KedU38
Other DBs
COG: COG0331 COG3321
Genes
AG: AFV52200(kedU38)
Reference
  Authors
Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B
  Title
Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.
  Journal
Mol Biosyst 9:478-91 (2013)
DOI:10.1039/c3mb25523a
  Sequence
LinkDB

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