KEGG   ORTHOLOGY: K21261
Entry
K21261                      KO                                     
Symbol
calO4
Name
acyltransferase
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Reaction
R11419  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21261  calO4; acyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21261  calO4; acyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Others
   K21261  calO4; acyltransferase
Other DBs
COG: COG0332
Genes
SFIY: F0344_26045
AMOG: QRX60_31730
SAQ: Sare_2030
AG: AAM70354(calO4)
Reference
PMID:12183629
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
[ag:AAM70354]
LinkDB

KEGG   REACTION: R11419
Entry
R11419                      Reaction                               
Definition
4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0 + 5-Iodo-2,3-dimethoxyorsellinate-[acp] <=> Calicheamicin PsAg + Acyl-carrier protein
Equation
C21339 + C21347 <=> C21340 + C00229
Reaction class
RC00039  C00229_C21347
RC03435  C21339_C21340
Pathway
rn01059  Biosynthesis of enediyne antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Orthology
K21261  acyltransferase
LinkDB

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