KEGG   ORTHOLOGY: K21335
Entry
K21335                      KO                                     
Symbol
calS10, atmS10
Name
dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase [EC:2.1.1.-]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R11476  S-adenosyl-L-methionine:dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K21335  calS10, atmS10; dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase
Genes
PKP: SK3146_06834(tylM1)
SLF: JEQ17_40460
SNIG: HEK616_47500
SJN: RI060_18325
SHAU: K9S39_40585
SKG: KJK29_16125
TALX: FOF52_07475
ACIR: OG979_40460 OG979_40540
SPIQ: OHA34_37515
NGN: LCN96_24350
SAQ: Sare_2049
AG: AAM70334(calS10) ABC02787(atmS10)
 » show all
Reference
  Authors
Peltier-Pain P, Singh S, Thorson JS
  Title
Characterization of Early Enzymes Involved in TDP-Aminodideoxypentose Biosynthesis en Route to Indolocarbazole AT2433.
  Journal
Chembiochem 16:2141-6 (2015)
DOI:10.1002/cbic.201500365
Reference
PMID:12183629 (calS10)
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
PMID:16873021 (atmS10)
  Authors
Gao Q, Zhang C, Blanchard S, Thorson JS
  Title
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.
  Journal
Chem Biol 13:733-43 (2006)
DOI:10.1016/j.chembiol.2006.05.009
  Sequence
LinkDB

KEGG   REACTION: R11476
Entry
R11476                      Reaction                               
Name
S-adenosyl-L-methionine:dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase
Definition
S-Adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-Adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose
Equation
Comment
deduced reaction
Reaction class
RC02262  C21354_C21355
Enzyme
2.1.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R11476  S-Adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-Adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose
Orthology
K21335  dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase [EC:2.1.1.-]
LinkDB

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