KEGG   ORTHOLOGY: K21374
Entry
K21374            Tight     KO                                     
Symbol
UGT85A23_24
Name
7-deoxyloganetin glucosyltransferase [EC:2.4.1.324]
Pathway
map00902  Monoterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R10835  UDP-alpha-D-glucose:7-deoxyloganetin O-D-glucosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00902 Monoterpenoid biosynthesis
    K21374  UGT85A23_24; 7-deoxyloganetin glucosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K21374  UGT85A23_24; 7-deoxyloganetin glucosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.324  7-deoxyloganetin glucosyltransferase
     K21374  UGT85A23_24; 7-deoxyloganetin glucosyltransferase
Glycosyltransferases [BR:ko01003]
 Others
  Hydrophobic molecule
   K21374  UGT85A23_24; 7-deoxyloganetin glucosyltransferase
Other DBs
CAZy: GT1
Genes
AG: BAK55737(UGT85A24) BAK55749(UGT85A23)
Reference
  Authors
Nagatoshi M, Terasaka K, Nagatsu A, Mizukami H
  Title
Iridoid-specific glucosyltransferase from Gardenia jasminoides.
  Journal
J Biol Chem 286:32866-74 (2011)
DOI:10.1074/jbc.M111.242586
  Sequence
Reference
  Authors
Asada K, Salim V, Masada-Atsumi S, Edmunds E, Nagatoshi M, Terasaka K, Mizukami H, De Luca V
  Title
A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle.
  Journal
Plant Cell 25:4123-34 (2013)
DOI:10.1105/tpc.113.115154
  Sequence
LinkDB

KEGG   ENZYME: 2.4.1.324
Entry
EC 2.4.1.324                Enzyme                                 
Name
7-deoxyloganetin glucosyltransferase;
UDPglucose:iridoid glucosyltransferase;
UGT6;
UGT85A24
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-glucose:7-deoxyloganetin O-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + 7-deoxyloganetin = UDP + 7-deoxyloganin [RN:R10835]
Reaction(KEGG)
R10835
Substrate
UDP-alpha-D-glucose [CPD:C00029];
7-deoxyloganetin [CPD:C20790]
Product
UDP [CPD:C00015];
7-deoxyloganin [CPD:C06071]
Comment
Isolated from the plants Catharanthus roseus (Madagascar periwinkle) and Gardenia jasminoides (cape jasmine). With Gardenia it also acts on genipin. Involved in loganin and secologanin biosynthesis. Does not react with 7-deoxyloganetate. cf. EC 2.4.1.323 7-deoxyloganetic acid glucosyltransferase.
History
EC 2.4.1.324 created 2014
Pathway
ec00902  Monoterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K21374  7-deoxyloganetin glucosyltransferase
Reference
1  [PMID:21799001]
  Authors
Nagatoshi M, Terasaka K, Nagatsu A, Mizukami H
  Title
Iridoid-specific glucosyltransferase from Gardenia jasminoides.
  Journal
J Biol Chem 286:32866-74 (2011)
DOI:10.1074/jbc.M111.242586
  Sequence
Reference
2  [PMID:24104568]
  Authors
Asada K, Salim V, Masada-Atsumi S, Edmunds E, Nagatoshi M, Terasaka K, Mizukami H, De Luca V
  Title
A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle.
  Journal
Plant Cell 25:4123-34 (2013)
DOI:10.1105/tpc.113.115154
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.324
IUBMB Enzyme Nomenclature: 2.4.1.324
ExPASy - ENZYME nomenclature database: 2.4.1.324
BRENDA, the Enzyme Database: 2.4.1.324
LinkDB

KEGG   REACTION: R10835
Entry
R10835                      Reaction                               
Name
UDP-alpha-D-glucose:7-deoxyloganetin O-D-glucosyltransferase
Definition
UDP-glucose + 7-Deoxyloganetin <=> UDP + Deoxyloganin
Equation
Reaction class
RC00005  C00015_C00029
RC00049  C06071_C20790
Enzyme
Pathway
rn00902  Monoterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.324
     R10835  UDP-glucose + 7-Deoxyloganetin <=> UDP + Deoxyloganin
Glycosyltransferase reactions [BR:br08203]
 Glucosyltransferase reactions
  R10835  Glc b1- Deoxyloganin
Orthology
K21374  7-deoxyloganetin glucosyltransferase [EC:2.4.1.324]
Other DBs
RHEA: 39902
LinkDB

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