KEGG   ORTHOLOGY: K21624
Entry
K21624                      KO                                     
Symbol
c3lhypd
Name
cis-L-3-hydroxyproline dehydratase [EC:4.2.1.171]
Pathway
map00330  Arginine and proline metabolism
Reaction
R11625  cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K21624  c3lhypd; cis-L-3-hydroxyproline dehydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.171  cis-L-3-hydroxyproline dehydratase
     K21624  c3lhypd; cis-L-3-hydroxyproline dehydratase
Other DBs
COG: COG4948
Genes
PAO: Pat9b_4270
PSET: THL1_3344
PVW: HU752_019980
MBS: MRBBS_3090(tfdDII)
MPQ: ABA45_14590
MSQ: BKP64_15685
MARA: D0851_07090
MANP: EHN06_15625
MSAN: LPB19_16680
MNK: RE428_12230
MMEE: NLK58_07890
NJO: ABXT42_09255
ABC: ACICU_02599
ABX: ABK1_2717
ABZ: ABZJ_02793
ABR: ABTJ_01114
ABD: ABTW07_2847
ABH: M3Q_2866
ABJ: BJAB07104_02757
ABAJ: BJAB0868_02639
ABW: BL01_04805
AVIV: LF296_05015
SHEM: HWQ47_23085
TLO: J9253_15835 J9253_15855
THIP: N838_12815 N838_12860 N838_12870
SPIU: SPICUR_01015
SROS: BBH56_00085
HSI: BOX17_15820
MRZ: KDW95_05240
THIN: CRN91_06570
BYI: BYI23_C003400
PSAA: QEN71_36505
BUE: BRPE67_CCDS08810
CDN: BN940_10836
CENP: M9799_16870
MLO: mll7353
MLN: A9174_28980
MCI: Mesci_5127 Mesci_5761
MCIC: A4R28_01460
MOP: Mesop_5709 Mesop_6338
MAM: Mesau_05204 Mesau_05810
MAMO: A6B35_11260 A6B35_31395 A6B35_31430
MESW: A9K65_028120
MESM: EJ066_15875
MESP: C1M53_25745
MHUA: MCHK_0861
MJR: EB229_29560
MERD: EB233_25595
MOH: IHQ72_30340
MMEI: LRP31_29715
MESJ: MJ8_18320
MESI: LGH82_11675
MESU: LHFGNBLO_005515
MEWS: QAZ47_29055
MEWM: QAZ22_29160
MEAA: ACG873_25555
NKI: KW403_09930
NRH: T8J41_04005
NTU: NTH_02373
AAK: AA2016_4178
AMIH: CO731_04096(ykfB)
AMIS: Amn_22550
ANJ: AMD1_4117
AMIO: N7E70_020625
PHT: BLM14_28020
PPED: LLE51_006950
AMAX: ABWH92_03180
RHI: NGR_c20510
SFH: SFHH103_04919
EMX: FKV68_08830 FKV68_29340
ENP: JVX98_03955
RLT: Rleg2_2920 Rleg2_6270
RAD: CO657_07130 CO657_14970
ROY: G3A56_25895 G3A56_27920
RHIZ: QMO80_003708
BRAB: RX331_25325
STAR: G3545_19660
SNO: Snov_0156
ANC: GBB76_15705
APRA: G3A50_11695
APOL: K9D25_02010
DEQ: XM25_06480
DAG: PSQ19_00040
DRP: PSQ90_03085
MMYR: MXMO3_02558
YTI: FNA67_10595
MHAR: L1P08_15150
LAP: ACP90_03845
LABR: CHH27_14510 CHH27_14515 CHH27_14520 CHH27_16900
LABP: FJ695_09465 FJ695_25345 FJ695_25350 FJ695_25355
LABT: FIU93_09480(hpbD2)
LAGG: B0E33_15405
RPOP: K1718_06480 K1718_06485 K1718_27215
RAGG: QUB73_04835
SIL: SPO1594 SPO1595
RUA: D1823_12765 D1823_12770 D1823_12775 D1823_21560
RUT: FIU92_00705(hpbD1) FIU92_00710(hpbD2) FIU92_00715(hpbD3) FIU92_20915(hpbD5)
RCON: K3740_13660
RUY: NOR97_00395 NOR97_00400 NOR97_19640
LMD: METH_03715 METH_03720 METH_21600
LEJ: ETW24_04555 ETW24_04565 ETW24_21125
LAQU: R2C4_00195
LEV: ETW23_15635 ETW23_15645 ETW23_22605
LCAE: K3721_03860 K3721_19995
LEIM: K3557_13825 K3557_13835
SULZ: C1J03_24310 C1J03_24880
SULI: C1J05_17360
ROM: EI983_11265 EI983_11280 EI983_11285
ROH: FIU89_04720(hpbD)
RPHC: RZ517_08190 RZ517_08200 RZ517_08210 RZ517_08215 RZ517_15890
RRL: RZS32_001540 RZS32_001545 RZS32_001555 RZS32_001565
AHT: ANTHELSMS3_01689
ASCA: QEZ52_11040 QEZ52_16335 QEZ52_16340
ACLD: ACIRQ6_17365 ACIRQ6_17370 ACIRQ6_17375
PPAN: ESD82_09265
PFEO: E3U26_15715
PAED: G5B38_08205 G5B38_08210
CACT: HZ995_06700 HZ995_06705 HZ995_06920
AMYL: QBD29_01610 QBD29_15440 QBD29_15445
PBAE: P8S53_16060
BOSG: GKR98_13460 GKR98_13465
NTN: D5366_04125
HTQ: FRZ44_05750
HADH: FRZ61_05880
APM: HIMB5_00009000
APB: SAR116_0305
ALK: ALEK_0483
ROO: G5S37_15600
PSL: Psta_4279
PIR: VN12_04975(hpbD)
RUL: UC8_12350(hpbD)
RML: FF011L_25140(hpbD)
ROL: CA51_17900(hpbD)
RUV: EC9_16410(hpbD)
RCF: Poly24_22630(hpbD)
AHEL: Q31a_31920(hpbD)
LCRE: Pla8534_37390(hpbD)
BVO: Pan97_28130(hpbD)
BREM: PSR63_25240
RLC: K227x_20600(hpbD)
SMAM: Mal15_54400(hpbD)
SNEP: Enr13x_18630(hpbD)
SMAE: TBK1r_28770(hpbD)
PLM: Plim_2539
PEH: Spb1_33100(hpbD)
FMR: Fuma_04875(ykfB_3)
GFM: Enr17x_02110(hpbD)
GAW: V144x_54800(hpbD)
MRI: Mal4_18100(hpbD)
TPOL: Mal48_25250(hpbD)
PVAR: SH412_000371
CCOP: Mal65_51760(hpbD)
SCHL: QJS52_21450
SSPE: ACGY09_08345
GES: VT84_28150(hpbD)
GOG: C1280_02595
GMS: SOIL9_51450
TIM: GMBLW1_09120
LRS: PX52LOC_08191
FTJ: FTUN_7844
ULI: ETAA1_44860(hpbD)
TSPH: KIH39_25405
AGV: OJF2_01180(hpbD)
HBS: IPV69_07755
PFER: IRI77_22655
GBA: J421_4704
MDX: BTO20_21610
MMAG: MMAD_17950
ROP: ROP_33630
ROA: Pd630_LPD07639
RKO: JWS14_15390
RHWY: GFS60_01884(catB)
SVL: Strvi_4532
SPHV: F9278_41770
MANT: BHD05_12270
ARQ: BWQ92_12360
CCYC: SCMU_39940
PROP: QQ658_07770
OCF: WJM97_15600
HDF: AArcSl_2466
AG: EAV42585(c3LHypD)
 » show all
Reference
PMID:25608448
  Authors
Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA
  Title
A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily.
  Journal
J Am Chem Soc 137:1388-91 (2015)
DOI:10.1021/ja5103986
  Sequence
[ag:EAV42585]
LinkDB

KEGG   ORTHOLOGY: K09123
Entry
K09123                      KO                                     
Symbol
lhpI
Name
cis-L-3-hydroxyproline dehydratase [EC:4.2.1.171]
Pathway
map00330  Arginine and proline metabolism
Reaction
R11625  cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K09123  lhpI; cis-L-3-hydroxyproline dehydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.171  cis-L-3-hydroxyproline dehydratase
     K09123  lhpI; cis-L-3-hydroxyproline dehydratase
Other DBs
COG: COG1679
Genes
FGR: FGSG_12672
FPU: FPSE_04942
FVN: FVRRES_08487
FVR: FVEG_06026
FOX: FOXG_08647
NHE: NECHADRAFT_47437 NECHADRAFT_75968
FFC: NCS54_00212200 NCS54_00358700
FKR: NCS57_00207300 NCS57_00364200
FMU: J7337_004742
TRE: TRIREDRAFT_59073
TRR: M419DRAFT_74960
TATV: 25777700(TrAtP1_009533)
TASP: 36611872(TrAFT101_011592)
PLJ: 28886251(PLICBS_007736)
PTKZ: JDV02_004404
CFJ: CFIO01_08286
CHIG: CH63R_05392
CDET: 87948356(CDEST_11856)
PFY: PFICI_14003
ANI: ANIA_08629
AFM: AFUA_6G00490
NFI: NFIA_047620
AOR: AO090005000232 AO090011000420
ANG: An05g02230
AFV: AFLA_003015 AFLA_007807
ALUC: AKAW2_81366A
ACHE: ACHE_30838S
APUU: APUU_10326S APUU_12323S
PCS: N7525_011371
AALT: CC77DRAFT_973712
FFU: CLAFUR5_10550
CBET: CB0940_08741
CCAC: CcaHIS019_0400830(CcaverHIS019_0400830)
PTI: PHATRDRAFT_47407
FCY: FRACYDRAFT_147078
TPS: THAPSDRAFT_263799
AAF: AURANDRAFT_25937
EHX: EMIHUDRAFT_464728
SLIG: GTU79_12535
TCI: A7K98_03655
PAE: PA1259
PAEV: N297_1298
PAEI: N296_1298
PAU: PA14_47930
PAG: PLES_40531
PAF: PAM18_3772
PNC: NCGM2_2141
PAEB: NCGM1900_1317
PDK: PADK2_19355
PSG: G655_18875
PRP: M062_06850
PAEP: PA1S_19620
PAER: PA1R_gp4865
PAEM: U769_19460
PAEL: T223_20710
PAES: SCV20265_4155
PAEU: BN889_01338(acnD)
PAEG: AI22_14345
PAEC: M802_1295
PAEO: M801_1298
SECH: B18_18030
PMUI: G4G71_28390
PNT: G5B91_04390
PAP: PSPA7_4133
PPAA: B7D75_18885
POR: APT59_02410
PPSL: BJP27_16675
PFUV: NLK61_00825
PFE: PSF113_3724(acnD)
PZA: HU749_017235
PCG: AXG94_01235
PMED: E3Z27_15360
PBA: PSEBR_a3202
PBC: CD58_14035
PDR: H681_03730
PFZ: AV641_10920
PALK: PSAKL28_28670
PRH: LT40_08305
PFK: PFAS1_24885
PSET: THL1_3354
PUM: HGP31_13910
PGG: FX982_00231
PPSH: G5J76_14175
PVK: EPZ47_13980
PBZ: GN234_05105
PDW: BV82_1493
PVW: HU752_014605
PQI: KH389_15865
PAZE: KSS91_13940
PALV: KSS97_15470
PCAS: LOY40_14815
PTK: EXN22_15850
PKJ: Q1W70_21720
PCUC: PSH97_10615
PTRL: OU419_04155
PRHZ: CRX69_05425
PHEF: PSH57_16170
PBEJ: PSH84_17495
PBAM: NUH87_04880
PBEN: V6W80_02345
PBEZ: SBP02_04130
PBUB: V6B39_15065
PSML: V6P94_14425
PSMZ: V6L79_14615
PSWO: SD196_03940
PMOR: PMm318_A48530
PTHV: CE140_03830
PAGB: AWM79_20320
PBAB: AAEO81_09045
PKH: JLK41_24650
PSTT: CH92_01045
PDEN: F1C79_29240
PALC: A0T30_01495
MBS: MRBBS_3771
MPQ: ABA45_17665
HAM: HALO1339
HAFN: KF947_05040
HOL: HORIV_50720
HNP: SR894_14715
PLG: NCTC10937_03090(acnD_2)
XYK: GT347_12675
XYG: R9X41_13655
MESP: C1M53_22690
MESS: ABSY17_02495
SME: SM_b20269
SMK: Sinme_3904
SMQ: SinmeB_4401
SMX: SM11_pD1342
SMI: BN406_06397
SMEG: C770_GR4pD1328
SMEL: SM2011_b20269
SMER: DU99_32025
SMD: Smed_3862
SIX: BSY16_2983
ESJ: SJ05684_b60010
EAK: EKH55_4112
EMX: FKV68_18765
EGI: PZN02_002064
SKM: PZL22_001039
STEG: QA637_13150
SCHP: RB548_16670
EAD: OV14_a1338
EAH: FA04_26875
ECAA: J3R84_21105
ENP: JVX98_05445
EAW: ACEP9W_25910
ATU: Atu4683
ATA: AWN88_02300
AGR: AGROH133_09591
ATF: Ach5_44050
ARAI: ACN9MK_14555
AGC: BSY240_1189
AGT: EYD00_22635
ASAL: CFBP5507_15640
RIR: BN877_II1777
RPUS: CFBP5875_22530
ACUC: KZ699_23385
ALEG: CFBP4996_24750
AGRC: GSF67_16185
AGRZ: A6U84_21825
RLE: pRL120183
RLG: Rleg_2143
RHL: LPU83_0079
RHV: BA939_17435
RHR: CKA34_24580
RII: FFM53_000485
RRG: J3P73_13310
RROS: D4A92_14680
RAW: NE851_02080
ARO: B0909_14110
RBW: RLCC275e_10980
RHIB: I8E17_25755
RHIY: BLX90_21810
RHT: NT26_0740
RFV: RFYW14_00933
SHZ: shn_20870
SZO: K8M09_18915
PDES: FE840_011060
HOAX: ABWH89_21900
ASIT: N7E02_06440
BVES: QO058_19440
BOI: BLM15_16215
BOF: FQV39_07085
BOW: NWE53_04125
BAPA: BBC0178_003880
LNE: FZC33_04685
APRA: G3A50_17100
MOC: BB934_22210
MTEZ: HPT29_010405
PEM: OF122_09000
PLEO: OHA_1_00386
AUA: M673_01845
AUB: LXB15_02640
JAV: OXU80_05805
PAQT: E8L99_00855
ACUT: MRB58_03890
APAH: KB221_08735
SIL: SPO0606
JOV: P8627_10250
YPAC: CEW88_21655
SULD: B5M07_16970
SINL: DSM14862_03938
SFAV: PL335_15950
SDUB: R1T39_17435
RMM: ROSMUCSMR3_03766
ROK: RAK1035_2606
RPEL: N7U68_02680
HAT: RC74_17905
LSAL: KBK07_17620
RMAI: MACH21_04910
RBL: B6K69_11125
PDE: Pden_4854
PAMI: JCM7686_pAMI5p194
PCON: B0A89_11820
PARU: CYR75_12385
PARS: DRW48_02020
PAAK: FIU66_17575
PKD: F8A10_10085
PPAN: ESD82_09110
PSAN: HGN31_03530
PMEH: JWJ88_18830
PAEZ: PAE61_15555
PALS: PAF20_17090
GEH: HYN69_18950
GFU: KM031_16585
TAW: EI545_04775
PSEB: EOK75_17430
LIT: FPZ52_12375
PAED: G5B38_02540
PALW: PSAL_037680
CMAG: CBW24_05650
FAP: GR316_11095
AALK: LGT41_0005615
SINR: O5O51_10065
RHP: LPB142_00840
KSC: CD178_02790
SCIA: HUG15_20565
NCM: QNK12_12465
BHV: BLHYD_07880
MPH: MLP_31270
 » show all
Reference
PMID:27929065
  Authors
Watanabe S, Tajima K, Fujii S, Fukumori F, Hara R, Fukuda R, Miyazaki M, Kino K, Watanabe Y
  Title
Functional characterization of aconitase X as a cis-3-hydroxy-L-proline dehydratase.
  Journal
Sci Rep 6:38720 (2016)
DOI:10.1038/srep38720
  Sequence
[pae:PA1259]
LinkDB

KEGG   ENZYME: 4.2.1.171
Entry
EC 4.2.1.171                Enzyme                                 
Name
cis-L-3-hydroxyproline dehydratase;
cis-L-3-hydroxyproline hydro-lyase;
c3LHypD
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
Reaction(IUBMB)
cis-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O [RN:R11625]
Reaction(KEGG)
R11625
Substrate
cis-3-hydroxy-L-proline [CPD:C19706]
Product
1-pyrroline-2-carboxylate [CPD:C03564];
H2O [CPD:C00001]
History
EC 4.2.1.171 created 2017
Pathway
ec00330  Arginine and proline metabolism
Orthology
K09123  cis-L-3-hydroxyproline dehydratase
K21624  cis-L-3-hydroxyproline dehydratase
Genes
FGR: FGSG_12672
FPU: FPSE_04942
FVN: FVRRES_08487
FVR: FVEG_06026
FOX: FOXG_08647
NHE: NECHADRAFT_47437 NECHADRAFT_75968
FFC: NCS54_00212200 NCS54_00358700
FKR: NCS57_00207300 NCS57_00364200
FMU: J7337_004742
TRE: TRIREDRAFT_59073
TRR: M419DRAFT_74960
TATV: 25777700(TrAtP1_009533)
TASP: 36611872(TrAFT101_011592)
PLJ: 28886251(PLICBS_007736)
PTKZ: JDV02_004404
CFJ: CFIO01_08286
CHIG: CH63R_05392
CDET: 87948356(CDEST_11856)
PFY: PFICI_14003
ANI: ANIA_08629
AFM: AFUA_6G00490
NFI: NFIA_047620
AOR: AO090005000232 AO090011000420
ANG: An05g02230
AFV: AFLA_003015 AFLA_007807
ALUC: AKAW2_81366A
ACHE: ACHE_30838S
APUU: APUU_10326S APUU_12323S
PCS: N7525_011371
AALT: CC77DRAFT_973712
FFU: CLAFUR5_10550
CBET: CB0940_08741
CCAC: CcaHIS019_0400830(CcaverHIS019_0400830)
PTI: PHATRDRAFT_47407
FCY: FRACYDRAFT_147078
TPS: THAPSDRAFT_263799
AAF: AURANDRAFT_25937
EHX: EMIHUDRAFT_464728
SLIG: GTU79_12535
PAO: Pat9b_4270
TCI: A7K98_03655
PAE: PA1259
PAEV: N297_1298
PAEI: N296_1298
PAU: PA14_47930
PAG: PLES_40531
PAF: PAM18_3772
PNC: NCGM2_2141
PAEB: NCGM1900_1317
PDK: PADK2_19355
PSG: G655_18875
PRP: M062_06850
PAEP: PA1S_19620
PAER: PA1R_gp4865
PAEM: U769_19460
PAEL: T223_20710
PAES: SCV20265_4155
PAEU: BN889_01338(acnD)
PAEG: AI22_14345
PAEC: M802_1295
PAEO: M801_1298
SECH: B18_18030
PMUI: G4G71_28390
PNT: G5B91_04390
PAP: PSPA7_4133
PPAA: B7D75_18885
POR: APT59_02410
PPSL: BJP27_16675
PFUV: NLK61_00825
PFE: PSF113_3724(acnD)
PZA: HU749_017235
PCG: AXG94_01235
PMED: E3Z27_15360
PBA: PSEBR_a3202
PBC: CD58_14035
PDR: H681_03730
PFZ: AV641_10920
PALK: PSAKL28_28670
PRH: LT40_08305
PFK: PFAS1_24885
PSET: THL1_3344 THL1_3354
PUM: HGP31_13910
PGG: FX982_00231
PPSH: G5J76_14175
PVK: EPZ47_13980
PBZ: GN234_05105
PDW: BV82_1493
PVW: HU752_014605 HU752_019980
PQI: KH389_15865
PAZE: KSS91_13940
PALV: KSS97_15470
PCAS: LOY40_14815
PTK: EXN22_15850
PKJ: Q1W70_21720
PCUC: PSH97_10615
PTRL: OU419_04155
PRHZ: CRX69_05425
PHEF: PSH57_16170
PBEJ: PSH84_17495
PBAM: NUH87_04880
PBEN: V6W80_02345
PBEZ: SBP02_04130
PBUB: V6B39_15065
PSML: V6P94_14425
PSMZ: V6L79_14615
PSWO: SD196_03940
PMOR: PMm318_A48530
PTHV: CE140_03830
PAGB: AWM79_20320
PBAB: AAEO81_09045
PKH: JLK41_24650
PSTT: CH92_01045
PDEN: F1C79_29240
PALC: A0T30_01495
MBS: MRBBS_3090(tfdDII) MRBBS_3771
MPQ: ABA45_14590 ABA45_17665
MSQ: BKP64_15685
MARA: D0851_07090
MANP: EHN06_15625
MSAN: LPB19_16680
MNK: RE428_12230
MMEE: NLK58_07890
NJO: ABXT42_09255
ABC: ACICU_02599
ABX: ABK1_2717
ABZ: ABZJ_02793
ABR: ABTJ_01114
ABD: ABTW07_2847
ABH: M3Q_2866
ABJ: BJAB07104_02757
ABAJ: BJAB0868_02639
ABW: BL01_04805
AVIV: LF296_05015
SHEM: HWQ47_23085
TLO: J9253_15835 J9253_15855
THIP: N838_12815 N838_12860 N838_12870
SPIU: SPICUR_01015
SROS: BBH56_00085
HAM: HALO1339
HSI: BOX17_15820
HAFN: KF947_05040
HOL: HORIV_50720
HNP: SR894_14715
MRZ: KDW95_05240
THIN: CRN91_06570
BYI: BYI23_C003400
PSAA: QEN71_36505
PLG: NCTC10937_03090(acnD_2)
BUE: BRPE67_CCDS08810
CDN: BN940_10836
CENP: M9799_16870
XYK: GT347_12675
XYG: R9X41_13655
MLO: mll7353
MLN: A9174_28980
MCI: Mesci_5127 Mesci_5761
MCIC: A4R28_01460
MOP: Mesop_5709 Mesop_6338
MAM: Mesau_05204 Mesau_05810
MAMO: A6B35_11260 A6B35_31395 A6B35_31430
MESW: A9K65_028120
MESM: EJ066_15875
MESP: C1M53_22690 C1M53_25745
MHUA: MCHK_0861
MJR: EB229_29560
MERD: EB233_25595
MOH: IHQ72_30340
MMEI: LRP31_29715
MESJ: MJ8_18320
MESI: LGH82_11675
MESU: LHFGNBLO_005515
MESS: ABSY17_02495
MEWS: QAZ47_29055
MEWM: QAZ22_29160
MEAA: ACG873_25555
NKI: KW403_09930
NRH: T8J41_04005
NTU: NTH_02373
AAK: AA2016_4178
AMIH: CO731_04096(ykfB)
AMIS: Amn_22550
ANJ: AMD1_4117
AMIO: N7E70_020625
PHT: BLM14_28020
PPED: LLE51_006950
AMAX: ABWH92_03180
SME: SM_b20269
SMK: Sinme_3904
SMQ: SinmeB_4401
SMX: SM11_pD1342
SMI: BN406_06397
SMEG: C770_GR4pD1328
SMEL: SM2011_b20269
SMER: DU99_32025
SMD: Smed_3862
RHI: NGR_c20510
SFH: SFHH103_04919
SIX: BSY16_2983
ESJ: SJ05684_b60010
EAK: EKH55_4112
EMX: FKV68_08830 FKV68_18765 FKV68_29340
EGI: PZN02_002064
SKM: PZL22_001039
STEG: QA637_13150
SCHP: RB548_16670
EAD: OV14_a1338
EAH: FA04_26875
ECAA: J3R84_21105
ENP: JVX98_03955 JVX98_05445
EAW: ACEP9W_25910
ATU: Atu4683
ATA: AWN88_02300
AGR: AGROH133_09591
ATF: Ach5_44050
ARAI: ACN9MK_14555
AGC: BSY240_1189
AGT: EYD00_22635
ASAL: CFBP5507_15640
RIR: BN877_II1777
RPUS: CFBP5875_22530
ACUC: KZ699_23385
ALEG: CFBP4996_24750
AGRC: GSF67_16185
AGRZ: A6U84_21825
RLE: pRL120183
RLT: Rleg2_2920 Rleg2_6270
RLG: Rleg_2143
RHL: LPU83_0079
RHV: BA939_17435
RHR: CKA34_24580
RAD: CO657_07130 CO657_14970
ROY: G3A56_25895 G3A56_27920
RII: FFM53_000485
RRG: J3P73_13310
RROS: D4A92_14680
RAW: NE851_02080
ARO: B0909_14110
RBW: RLCC275e_10980
RHIZ: QMO80_003708
RHIB: I8E17_25755
RHIY: BLX90_21810
RHT: NT26_0740
RFV: RFYW14_00933
SHZ: shn_20870
SZO: K8M09_18915
PDES: FE840_011060
HOAX: ABWH89_21900
ASIT: N7E02_06440
BRAB: RX331_25325
BVES: QO058_19440
BOI: BLM15_16215
BOF: FQV39_07085
BOW: NWE53_04125
BAPA: BBC0178_003880
STAR: G3545_19660
LNE: FZC33_04685
SNO: Snov_0156
ANC: GBB76_15705
APRA: G3A50_11695 G3A50_17100
APOL: K9D25_02010
MOC: BB934_22210
MTEZ: HPT29_010405
PEM: OF122_09000
DEQ: XM25_06480
DAG: PSQ19_00040
DRP: PSQ90_03085
MMYR: MXMO3_02558
YTI: FNA67_10595
MHAR: L1P08_15150
PLEO: OHA_1_00386
AUA: M673_01845
AUB: LXB15_02640
JAV: OXU80_05805
LAP: ACP90_03845
LABR: CHH27_14510 CHH27_14515 CHH27_14520 CHH27_16900
LABP: FJ695_09465 FJ695_25345 FJ695_25350 FJ695_25355
LABT: FIU93_09480(hpbD2)
LAGG: B0E33_15405
RPOP: K1718_06480 K1718_06485 K1718_27215
RAGG: QUB73_04835
PAQT: E8L99_00855
ACUT: MRB58_03890
APAH: KB221_08735
SIL: SPO0606 SPO1594 SPO1595
RUA: D1823_12765 D1823_12770 D1823_12775 D1823_21560
RUT: FIU92_00705(hpbD1) FIU92_00710(hpbD2) FIU92_00715(hpbD3) FIU92_20915(hpbD5)
RCON: K3740_13660
RUY: NOR97_00395 NOR97_00400 NOR97_19640
JOV: P8627_10250
LMD: METH_03715 METH_03720 METH_21600
LEJ: ETW24_04555 ETW24_04565 ETW24_21125
LAQU: R2C4_00195
LEV: ETW23_15635 ETW23_15645 ETW23_22605
LCAE: K3721_03860 K3721_19995
LEIM: K3557_13825 K3557_13835
YPAC: CEW88_21655
SULZ: C1J03_24310 C1J03_24880
SULI: C1J05_17360
SULD: B5M07_16970
SINL: DSM14862_03938
SFAV: PL335_15950
SDUB: R1T39_17435
RMM: ROSMUCSMR3_03766
ROK: RAK1035_2606
ROM: EI983_11265 EI983_11280 EI983_11285
ROH: FIU89_04720(hpbD)
RPEL: N7U68_02680
RPHC: RZ517_08190 RZ517_08200 RZ517_08210 RZ517_08215 RZ517_15890
RRL: RZS32_001540 RZS32_001545 RZS32_001555 RZS32_001565
AHT: ANTHELSMS3_01689
HAT: RC74_17905
LSAL: KBK07_17620
RMAI: MACH21_04910
ASCA: QEZ52_11040 QEZ52_16335 QEZ52_16340
ACLD: ACIRQ6_17365 ACIRQ6_17370 ACIRQ6_17375
RBL: B6K69_11125
PDE: Pden_4854
PAMI: JCM7686_pAMI5p194
PCON: B0A89_11820
PARU: CYR75_12385
PARS: DRW48_02020
PAAK: FIU66_17575
PKD: F8A10_10085
PPAN: ESD82_09110 ESD82_09265
PSAN: HGN31_03530
PMEH: JWJ88_18830
PAEZ: PAE61_15555
PALS: PAF20_17090
PFEO: E3U26_15715
GEH: HYN69_18950
GFU: KM031_16585
TAW: EI545_04775
PSEB: EOK75_17430
LIT: FPZ52_12375
PAED: G5B38_02540 G5B38_08205 G5B38_08210
PALW: PSAL_037680
CACT: HZ995_06700 HZ995_06705 HZ995_06920
CMAG: CBW24_05650
FAP: GR316_11095
AALK: LGT41_0005615
AMYL: QBD29_01610 QBD29_15440 QBD29_15445
PBAE: P8S53_16060
BOSG: GKR98_13460 GKR98_13465
SINR: O5O51_10065
RHP: LPB142_00840
KSC: CD178_02790
NTN: D5366_04125
HTQ: FRZ44_05750
HADH: FRZ61_05880
APM: HIMB5_00009000
APB: SAR116_0305
ALK: ALEK_0483
ROO: G5S37_15600
PSL: Psta_4279
PIR: VN12_04975(hpbD)
RUL: UC8_12350(hpbD)
RML: FF011L_25140(hpbD)
ROL: CA51_17900(hpbD)
RUV: EC9_16410(hpbD)
RCF: Poly24_22630(hpbD)
AHEL: Q31a_31920(hpbD)
LCRE: Pla8534_37390(hpbD)
BVO: Pan97_28130(hpbD)
BREM: PSR63_25240
RLC: K227x_20600(hpbD)
SMAM: Mal15_54400(hpbD)
SNEP: Enr13x_18630(hpbD)
SMAE: TBK1r_28770(hpbD)
PLM: Plim_2539
PEH: Spb1_33100(hpbD)
FMR: Fuma_04875(ykfB_3)
GFM: Enr17x_02110(hpbD)
GAW: V144x_54800(hpbD)
MRI: Mal4_18100(hpbD)
TPOL: Mal48_25250(hpbD)
PVAR: SH412_000371
CCOP: Mal65_51760(hpbD)
SCHL: QJS52_21450
SSPE: ACGY09_08345
GES: VT84_28150(hpbD)
GOG: C1280_02595
GMS: SOIL9_51450
TIM: GMBLW1_09120
LRS: PX52LOC_08191
FTJ: FTUN_7844
ULI: ETAA1_44860(hpbD)
TSPH: KIH39_25405
AGV: OJF2_01180(hpbD)
HBS: IPV69_07755
PFER: IRI77_22655
GBA: J421_4704
SCIA: HUG15_20565
NCM: QNK12_12465
BHV: BLHYD_07880
MDX: BTO20_21610
MMAG: MMAD_17950
ROP: ROP_33630
ROA: Pd630_LPD07639
RKO: JWS14_15390
RHWY: GFS60_01884(catB)
SVL: Strvi_4532
SPHV: F9278_41770
MANT: BHD05_12270
ARQ: BWQ92_12360
CCYC: SCMU_39940
MPH: MLP_31270
PROP: QQ658_07770
OCF: WJM97_15600
HDF: AArcSl_2466
 » show all
Reference
1  [PMID:25608448]
  Authors
Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA
  Title
A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily.
  Journal
J Am Chem Soc 137:1388-91 (2015)
DOI:10.1021/ja5103986
  Sequence
[ag:EAV42585]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.171
IUBMB Enzyme Nomenclature: 4.2.1.171
ExPASy - ENZYME nomenclature database: 4.2.1.171
BRENDA, the Enzyme Database: 4.2.1.171
LinkDB

KEGG   REACTION: R11625
Entry
R11625                      Reaction                               
Name
cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
Definition
cis-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O
Equation
C19706 <=> C03564 + C00001
Reaction class
RC01139  C03564_C19706
Enzyme
4.2.1.171
Pathway
rn00330  Arginine and proline metabolism
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.171
     R11625  cis-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O
Orthology
K09123  cis-L-3-hydroxyproline dehydratase [EC:4.2.1.171]
K21624  cis-L-3-hydroxyproline dehydratase [EC:4.2.1.171]
Other DBs
RHEA: 47627
LinkDB

DBGET integrated database retrieval system