KEGG   ORTHOLOGY: K21667
Entry
K21667            Tight     KO                                     

Name
vGPCR
Definition
KSHV G-protein coupled receptor
Pathway
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05203  Viral carcinogenesis
Network
nt06124  Chemokine signaling (viruses)
nt06150  Cytokine-cytokine receptor interaction (viruses)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06224  CXCR signaling
  Element
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N01218  CCL1 to KSHV vGPCR signaling
N01234  CXCL1/5/8 to KSHV vGPCR signaling
N01235  CXCL6 to KSHV vGPCR signaling
N01239  CXCL2/3/7 to KSHV vGPCR signaling
N01242  CXCL4 to KSHV vGPCR signaling
N01243  CXCL10 to KSHV vGPCR signaling
N01251  CXCL12 to KSHV vGPCR signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    K21667  vGPCR; KSHV G-protein coupled receptor
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K21667  vGPCR; KSHV G-protein coupled receptor
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K21667  vGPCR; KSHV G-protein coupled receptor
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21667  vGPCR; KSHV G-protein coupled receptor
Viral proteins [BR:ko03200]
 dsDNA viruses
  Kaposi's sarcoma-associated herpesvirus (Human herpesvirus 8)
   K21667  vGPCR; KSHV G-protein coupled receptor
Genes
VG: 4961460(HHV8GK18_gp84)
Reference
PMID:8892957
  Authors
Cesarman E, Nador RG, Bai F, Bohenzky RA, Russo JJ, Moore PS, Chang Y, Knowles DM
  Title
Kaposi's sarcoma-associated herpesvirus contains G protein-coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma.
  Journal
J Virol 70:8218-23 (1996)
DOI:10.1128/JVI.70.11.8218-8223.1996
  Sequence
[vg:4961460]
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