KEGG   ORTHOLOGY: K21785
Entry
K21785                      KO                                     

Symbol
pigM, redV
Name
4-hydroxy-2,2'-bipyrrole-5-methanol dehydrogenase
Pathway
map00333  Prodigiosin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21785  pigM, redV; 4-hydroxy-2,2'-bipyrrole-5-methanol dehydrogenase
Other DBs
RN: R11668 R11669
Genes
SMW: SMWW4_v1c10920(pigM)
SRR: SerAS9_1741
SRS: SerAS12_1741
SRA: SerAS13_1742
SERF: L085_23090
SERA: Ser39006_020635
SERQ: CWC46_20640
SERM: CLM71_22550
SSUR: ATE40_002175
VGA: BSQ33_01015
VSR: Vspart_01691(pigM)
HCH: HCH_06036
SCO: SCO5882(redV)
STRD: NI25_09820
AG: CAH55641(pigM)
 » show all
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence
LinkDB

KEGG   REACTION: R11668
Entry
R11668                      Reaction                               

Name
4-hydroxy-2,2'-bipyrrole-5-methanal:NADP+ oxidoreductase
Definition
4-Hydroxy-2,2'-bipyrrole-5-methanol + NADP+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADPH + H+
Equation
Comment
NAD+ (see R11669)
Reaction class
RC00116  C21568_C21569
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Orthology
K21785  4-hydroxy-2,2'-bipyrrole-5-methanol dehydrogenase
LinkDB

KEGG   REACTION: R11669
Entry
R11669                      Reaction                               

Name
4-hydroxy-2,2'-bipyrrole-5-methanal:NAD+ oxidoreductase
Definition
4-Hydroxy-2,2'-bipyrrole-5-methanol + NAD+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADH + H+
Equation
Comment
NADP+ (see R11668)
Reaction class
RC00116  C21568_C21569
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Orthology
K21785  4-hydroxy-2,2'-bipyrrole-5-methanol dehydrogenase
LinkDB

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