KEGG   ORTHOLOGY: K21883
Entry
K21883                      KO                                     
Symbol
lra5
Name
2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) [EC:1.1.1.401]
Pathway
map00051  Fructose and mannose metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K21883  lra5; 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.401  2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
     K21883  lra5; 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
Other DBs
RN: R11339
COG: COG1028
Genes
XAX: XACM_2065
XFU: XFF4834R_chr21390
XPE: BJD13_06130
XPH: XppCFBP6546_02695(XppCFBP6546P_02695)
XAN: AC801_10760
XTH: G4Q83_12700
SML: Smlt2912
SMT: Smal_2364
BUJ: BurJV3_2418
SMZ: SMD_2548
SINC: DAIF1_25010(linC)
PPF: Pput_2199
PPI: YSA_00165
PPX: T1E_2289
PPUT: L483_18725
PPUN: PP4_22550
GAI: IMCC3135_16660(fabG_4)
HOL: HORIV_71480(fabG_2)
REH: H16_B1075(h16_B1075)
CNC: CNE_2c10320(fabG7) CNE_BB1p11630(fabG16)
CGD: CR3_3352(fabG)
BFN: OI25_6822
PDIO: PDMSB3_2084.1(LRA)
PPUL: RO07_13835
CABA: SBC2_60230(LRA5)
PVAC: HC248_01488(lra5)
VEI: Veis_0638
RTA: Rta_09040
LIM: L103DPR2_00634(fabG_5)
LIH: L63ED372_02617(fabG_7)
HSE: Hsero_0584(fabG) Hsero_1263(fabG)
HRB: Hrubri_1079(fabG)
URU: DSM104443_01671(lra5)
UPL: DSM104440_01594(lra5)
ALK: ALEK_0863
HEBR: AEBR_0817
ATU: Atu3813(fabG) Atu4595
RLE: RL2674
RLG: Rleg_2210
NEN: NCHU2750_48930(fabG)
KAI: K32_02130
BJA: bll3655(bll3655) bll3913(fabG) bll6359(bll6359)
BRA: BRADO3101
BBT: BBta_3549
BRS: S23_43210(fabG)
AOL: S58_45070
BRAD: BF49_1142
BRO: BRAD285_2845(fabG)
BARH: WN72_21055
BEL: BE61_63390(fabG)
RPA: RPA3474(fabG4)
RPB: RPB_2093
RPC: RPC_3650
RPD: RPD_3326
RPE: RPE_3690
RPT: Rpal_3964
VGO: GJW-30_1_00198(fabG_1)
XAU: Xaut_1907
AZC: AZC_2269
SNO: Snov_4089
MET: M446_4913
MAQU: Maq22A_c13140(fabG)
MIND: mvi_05200
HDI: HDIA_4541(fabG_25)
MMED: Mame_04374(actIII_3)
RBM: TEF_05635
TSV: DSM104635_01778(fabG_4)
SIL: SPO2413
RUT: FIU92_00170(fabG1)
RDE: RD1_3872
KRO: BVG79_p1000086(fabG)
SPSE: SULPSESMR1_01364(fabG)
MALU: KU6B_07020
RSP: RSP_3888(fabG)
HBA: Hbal_2758
SPHI: TS85_02210
SSAN: NX02_22765
SPHR: BSY17_3164
BLAS: BSY18_1711
ACR: Acry_2467
GDI: GDI3269
GDJ: Gdia_3096
GXY: GLX_03410
GXL: H845_1309
KEU: S101446_00441(butA)
SHUM: STHU_24740(fabG_3)
SVC: STVA_30890(fabG_3)
STEL: STAQ_22350(fabG_5)
HADH: FRZ61_45110(fabG)
PSAB: PSAB_03640
CGT: cgR_2332
CCYC: SCMU_10800
RER: RER_46900
REY: O5Y_22145
ROP: ROP_15410
ACH: Achl_0572
NAL: B005_2522
GOB: Gobs_2441
PAUT: Pdca_38240(fabG_8)
CTHE: Chro_4734
SDYN: Mal52_25750(fabG_5)
GES: VT84_10250(fabG_6)
ULI: ETAA1_18450(fabG_5)
SACI: Sinac_5872
PBOR: BSF38_05220(tsaC1)
ABAS: ACPOL_0913
PHE: Phep_2313
SLI: Slin_0608
DFE: Dfer_3040
ALAM: RT761_01057(lRA5)
AG: EAT09364(LRA5)
 » show all
Reference
  Authors
Watanabe S, Makino K
  Title
Novel modified version of nonphosphorylated sugar metabolism--an alternative L-rhamnose pathway of Sphingomonas sp.
  Journal
FEBS J 276:1554-67 (2009)
DOI:10.1111/j.1742-4658.2009.06885.x
  Sequence
LinkDB

KEGG   ENZYME: 1.1.1.401
Entry
EC 1.1.1.401                Enzyme                                 
Name
2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+);
2-keto-3-deoxy-L-rhamnonate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
2-dehydro-3-deoxy-L-rhamnonate:NAD+ 4-oxidoreductase
Reaction(IUBMB)
2-dehydro-3-deoxy-L-rhamnonate + NAD+ = 2,4-didehydro-3-deoxy-L-rhamnonate + NADH + H+ [RN:R11339]
Reaction(KEGG)
R11339
Substrate
2-dehydro-3-deoxy-L-rhamnonate [CPD:C03979];
NAD+ [CPD:C00003]
Product
2,4-didehydro-3-deoxy-L-rhamnonate [CPD:C20781];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the bacteria Sphingomonas sp. SKA58 and Sulfobacillus thermosulfidooxidans, is involved in the non-phosphorylative degradation pathway for L-rhamnose. It does not show any detectable activity with NADP+ or with other aldoses.
History
EC 1.1.1.401 created 2016
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K21883  2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
Genes
XAXXACM_2065
XFUXFF4834R_chr21390
XPEBJD13_06130
XPHXppCFBP6546_02695(XppCFBP6546P_02695)
XANAC801_10760
XTHG4Q83_12700
SMLSmlt2912
SMTSmal_2364
BUJBurJV3_2418
SMZSMD_2548
SRHBAY15_2207
SLMBIZ42_01235
STENCCR98_12530
STEMCLM74_12860
STESMG068_12375
SINCDAIF1_25010(linC)
SPAQSTNY_R25550
PPFPput_2199
PPGPputGB1_2345
PPWPputW619_2844
PPIYSA_00165
PPXT1E_2289
PPUTL483_18725
PPUNPP4_22550
PEZHWQ56_14835
HAESLO767_10730
GAIIMCC3135_16660(fabG_4)
HOLHORIV_71480(fabG_2)
MMEMarme_1649
LLPGH975_02675
JEUBJP62_03425
REHH16_B1075(h16_B1075)
CNCCNE_2c10320(fabG7) CNE_BB1p11630(fabG16)
CGDCR3_3352(fabG)
CCUPBKK81_19460
CUPBKK80_22485
CUUBKK79_27725
BACBamMC406_1205
BUGBC1001_3866
BGFBC1003_5542
BYIBYI23_B004390 BYI23_B007570 BYI23_C012390 BYI23_D004990
BUEBRPE67_BCDS07010 BRPE67_BCDS11520 BRPE67_CCDS14200 BRPE67_DCDS06790
BUQAC233_21665
BUMAXG89_17650 AXG89_39135
BUIAX768_21210 AX768_27430
BXEBxe_A2719 Bxe_B1028 Bxe_C0296
BXBDR64_403 DR64_6349 DR64_8137
BPHBphy_3470 Bphy_6096 Bphy_6716
BGEBC1002_4239
BPXBUPH_00440
BPYBphyt_5691
BFNOI25_6822
BCAIK788_0006074 K788_0008440 K788_0008516
PSPWBJG93_25600
PARABTO02_31840
PARBCJU94_23875 CJU94_35365
PHSC2L64_21010 C2L64_22515 C2L64_33470 C2L64_40795
PTERC2L65_25445 C2L65_30060
PGPCUJ91_21865
PCJCUJ87_23080 CUJ87_29425
PTSCUJ90_29515
PCAFDSC91_001130
PMEGFNZ07_09770
PTROG5S35_23000 G5S35_23835
PGISI6I06_22805 I6I06_24305
PACPFAZ97_21170 FAZ97_29965
PACSFAZ98_17360 FAZ98_27105
PEWKZJ38_34640
PDIOPDMSB3_2084.1(LRA)
PPULRO07_13835
CABASBC2_60230(LRA5)
BUOBRPE64_BCDS05680 BRPE64_BCDS08830 BRPE64_CCDS02950
BBROBAU06_17515
BFZBAU07_03410 BAU07_08710
BOHAKI39_16775 AKI39_21445
BOJCBF45_16040
PUSCKA81_16410
AKATKWG_22980 TKWG_24470
AMIMMIM_c37220 MIM_c39460
PIGEGT29_25860
PACRFXN63_19505
KGYEHF36_16085
PARKLSG25_14995
RHYRD110_04410 RD110_09810 RD110_13105 RD110_25030
RHFEUB48_18795
POLBpro_1491 Bpro_3960
POSDT070_03350
POOF7R28_06085
PVACHC248_01488(lra5)
AMONH9L24_05015
AANTHUK68_21720
VEIVeis_0638
VAPVapar_0789
VPEVarpa_0812 Varpa_4230
VPDVAPA_1c08500 VAPA_1c34560 VAPA_1c40710
VAAAX767_07345
VBOCKY39_03990 CKY39_23990
VAMC4F17_15270
CODOLAD35_14540
RTARta_09040
LIML103DPR2_00634(fabG_5)
LIHL63ED372_02617(fabG_7)
JAJEKL02_03045
HSEHsero_0584(fabG) Hsero_1263(fabG)
HSZACP92_02925 ACP92_06345
HHTF506_05085 F506_06205
HRBHrubri_1079(fabG)
HEEhmeg3_06350 hmeg3_20535
HHFE2K99_03270 E2K99_06180
HFRG5S34_03150 G5S34_06475
RGUA4W93_06530
XYKGT347_22460
URUDSM104443_01671(lra5)
UPLDSM104440_01594(lra5)
BEBABWI17_18635
ANTArnit_0850
ALKALEK_0863
ALPLPB137_03815
HEBRAEBR_0817
MLOmll5243 mlr7680
MLNA9174_01320 A9174_27675
MCIMesci_0269 Mesci_0299
MOPMesop_0255
MAMMesau_00256
MAMOA6B35_06440
MESWA9K65_001345 A9K65_001495 A9K65_021660
MESMEJ066_10000
MESPC1M53_17335 C1M53_28885
MHUAMCHK_1138 MCHK_6293
MJREB229_01345 EB229_27935
MERDEB233_01420
MESMeso_0411 Meso_0784
HOEIMCC20628_00090
PHTBLM14_17760
RPODE0E05_09135
NKIKW403_18990
KMNHW532_07945
ATUAtu3813(fabG) Atu4595
AGRAGROH133_09944
AROB0909_14590
RLERL2674
RLGRleg_2210
RLBRLEG3_21705
RGARGR602_PC01505
RIIFFM53_000160
NENNCHU2750_48930(fabG)
RFVRFYW14_03817
ABAWD5400_03555
KAIK32_02130
OINIAR37_20445
OCHCES85_3153
OCRHGK82_17775
BJAbll3655(bll3655) bll3913(fabG) bll6359(bll6359)
BJUBJ6T_59230
BJPRN69_28710
BRABRADO3101
BBTBBta_3549
BRSS23_43210(fabG)
AOLS58_45070
BRCBCCGELA001_16275
BRADBF49_1142
BICLMTR13_23485
BROBRAD285_2845(fabG)
BRKCWS35_27950
BOTCIT37_34445
BRQCIT40_12295
BGQX265_23805
BGZXH91_20995
BSYMCIT39_11545
BBETF8237_02255
BARHWN72_21055
BVZBRAD3257_2220 BRAD3257_5027 BRAD3257_5135(fabG)
BELBE61_63390(fabG)
BDGLPJ38_21680
BSEPHAP48_0034515
BQBJ4P68_0035760
RPARPA3474(fabG4)
RPBRPB_2093
RPCRPC_3650
RPDRPD_3326
RPERPE_3690
RPTRpal_3964
RPXRpdx1_1900
RBKE0H22_11315 E0H22_14510
VGOGJW-30_1_00198(fabG_1)
TRBHB776_05295
BOPAXW83_06685 AXW83_15660 AXW83_15690 AXW83_20390
BOSBSY19_1292 BSY19_346
BVVBHK69_05300 BHK69_29605
BOIBLM15_15895 BLM15_16500 BLM15_19670
BOFFQV39_13175 FQV39_13575 FQV39_14755 FQV39_17890 FQV39_19460 FQV39_30970
XAUXaut_1907
XDIEZH22_08125 EZH22_12750
AZCAZC_2269
SNOSnov_4089
STARG3545_16255 G3545_27160
LNEFZC33_13720 FZC33_22295 FZC33_26780
APRAG3A50_04745 G3A50_07825
METM446_4913
MNOMnod_2255 Mnod_2895 Mnod_6624
MAQUMaq22A_c13140(fabG)
MEEDA075_05270
MTEADK419_12605
MINDmvi_05200
MOCBB934_14870 BB934_28775
MIVC4E04_19010
CHELAL346_08150 AL346_11895
CDQBOQ54_01270 BOQ54_04120
DEQXM25_05675
DEIC4375_11170
DEAFPZ08_14720 FPZ08_18035
DSALK1X15_16270
YTIFNA67_09780
HDIHDIA_4541(fabG_25)
MMEDMame_04374(actIII_3)
AALAIGS74_14650
AALMLUX29_16565
AUBLXB15_00395
PSINCAK95_01485
NOHG5V57_32705
RBMTEF_05635
SIWGH266_15815
PHRC6569_17890
PSTGE8M01_12015
ACUTMRB58_10395 MRB58_15425 MRB58_21970
CSECseg_1772 Cseg_2744
CFHC1707_14135
BSBBresu_2871
BRDJL11_06970
BRGA4249_07710
BREVE7T10_08355
BNDKWG56_07400
AEXAstex_2137
TSVDSM104635_01778(fabG_4)
SILSPO2413
RUAD1823_15630
RUTFIU92_00170(fabG1)
RDERD1_3872
RLIRLO149_c005630
KROBVG79_p1000086(fabG)
OATOAN307_c00740
YPACCEW88_23325
SULIC1J05_04655
SMEDJNX03_16185 JNX03_16965
SPSESULPSESMR1_01364(fabG)
TOMBWR18_20325
AHTANTHELSMS3_00521
SAGUCDO87_12725 CDO87_23165 CDO87_25655
OCDFHY55_06055
MALUKU6B_07020
HATRC74_03370
RSPRSP_3888(fabG)
RSHRsph17029_4152
RBLB6K69_17915
PYEA6J80_10075
PCONB0A89_00190
PMUTDPM13_08275
PSANHGN31_05485
PTPRCA23_c06680 RCA23_c11890 RCA23_c23530
SALOEF888_07675
LITFPZ52_13135
HDHG5B40_02135
FAQG5B39_10225
HBAHbal_2758
STAXMC45_07210 MC45_07305
SPHITS85_02210
SSANNX02_22765
SNJA7E77_11695
SMYBJP26_16660
SPANAWL63_05980
SKRBRX40_01505
SPLMBXU08_18015
SPHCCVN68_10775
SARIH5J25_00355
SSUAFPZ54_00330
SPHRBSY17_3164
SYAA6768_21740
SPYGYGS_C1P2518
BLASBSY18_1711
BFWB5J99_17935
SPHSETR14_07005
TFVIDJ81_03385
ACRAcry_2467
AMVACMV_27830
GDIGDI3269
GDJGdia_3096
GXYGLX_03410
GXLH845_1309
KNAB0W47_16360
KEUS101446_00441(butA)
KREGWK63_06515
RGIRGI145_21810 RGI145_22280
RMTIAI58_20555
SHUMSTHU_24740(fabG_3)
SVCSTVA_30890(fabG_3)
STELSTAQ_22350(fabG_5)
NAOY958_05035
NCBC0V82_17100 C0V82_24305
SKTIGS68_28120
SMUCJL100_031380
SROEJL101_033735 JL101_034715
FERFNB15_04205
HTQFRZ44_47260
HADHFRZ61_45110(fabG)
ELIOKO353_11810
PUBSAR11_0767 SAR11_0846 SAR11_0869
PELSAR11G3_00249
PEGE5R92_01630 E5R92_02215
APMHIMB5_00003580
APBSAR116_0926
PARHI5S86_15670
PSABPSAB_03640
CGTcgR_2332
CGSC624_11910
CGGC629_11920
CMDB841_00465
CCYCSCMU_10800
RHARHA1_ro01856
RERRER_46900
REYO5Y_22145
REBXU06_22260
RQIC1M55_23600
ROPROP_15410
ROAPd630_LPD06026
RAVAAT18_25275
RRZCS378_14855
RHODAOT96_03635
RKOJWS14_09535 JWS14_41825
RGOKYT97_30365
SKACP970_39490
MHOSCXR34_05710
MPRTET475_04325
MLZF6J85_08210
MALKMalAC0309_0327
ARRARUE_c18400
ARLAFL94_05110
ARYATC04_12775
ARTPE5206_14085
PNVJMY29_13020
ACHAchl_0572
APNAsphe3_04660
PSULAU252_01350
PSNINIBR502771_02820
GPRJQN66_05550
SATKSA2016_3915
BCVBcav_0122 Bcav_2984
HALTIM660_05995
NROK8W59_08275
AEZC3E78_14060
NALB005_2522
NOABKM31_10155
NOWGBF35_27275
GOBGobs_2441
SACGFDZ84_24815
PAUTPdca_38240(fabG_8)
PBROHOP40_26370
PSUUPsuf_070940
AEYCDG81_10675
PLANA1s21148_00900
PVSA1sIA79_05290
ABAMB1s21122_04950
NHIB1s21160_04755
ERZER308_18945
CTHEChro_4734
ROOG5S37_23950
SDYNMal52_25750(fabG_5)
GESVT84_10250(fabG_6)
GOGC1280_17780
GMSSOIL9_18330 SOIL9_49820
TIMGMBLW1_14200
LRSPX52LOC_06167
FTJFTUN_1341 FTUN_2607
ULIETAA1_18450(fabG_5)
TSPHKIH39_25055
SACISinac_5872
PBORBSF38_05220(tsaC1)
TALBFTW19_10835
ABASACPOL_0913
EDAGWR55_16765
FLASY85_11795
PGOFSB84_30420
FLCKJS93_09855 KJS93_18560
PHEPhep_2313
CMRCycma_1664
CAMUCA2015_1571
SLISlin_0608
SRDSD10_04060 SD10_11620
SMONAWR27_07945
SPIRCWM47_13545
SPIKEXU85_20030 EXU85_24690
SPIBG8759_20310
STAEHNV11_12675
RHOZGXP67_02250
DFEDfer_3040
RSIRunsl_1900
RUNDR864_18425
RUPDTQ70_25050
FBTD770_14490
CHKD4L85_32635
RBIRB2501_01515
AALGAREALGSMS7_01857
ALAMRT761_01057(lRA5)
 » show all
Reference
1  [PMID:19187228]
  Authors
Watanabe S, Makino K
  Title
Novel modified version of nonphosphorylated sugar metabolism--an alternative L-rhamnose pathway of Sphingomonas sp.
  Journal
FEBS J 276:1554-67 (2009)
DOI:10.1111/j.1742-4658.2009.06885.x
  Sequence
Reference
2  [PMID:25617114]
  Authors
Bae J, Kim SM, Lee SB
  Title
Identification and characterization of 2-keto-3-deoxy-L-rhamnonate dehydrogenase  belonging to the MDR superfamily from the thermoacidophilic bacterium Sulfobacillus thermosulfidooxidans: implications to L-rhamnose metabolism in archaea.
  Journal
Extremophiles 19:469-78 (2015)
DOI:10.1007/s00792-015-0731-8
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.401
IUBMB Enzyme Nomenclature: 1.1.1.401
ExPASy - ENZYME nomenclature database: 1.1.1.401
BRENDA, the Enzyme Database: 1.1.1.401
LinkDB

KEGG   REACTION: R11339
Entry
R11339                      Reaction                               
Name
2-dehydro-3-deoxy-L-rhamnonate:NAD+ 4-oxidoreductase
Definition
2-Dehydro-3-deoxy-L-rhamnonate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+
Equation
Reaction class
RC00089  C03979_C20781
Enzyme
Pathway
rn00051  Fructose and mannose metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K21883  2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) [EC:1.1.1.401]
Other DBs
RHEA: 36502
LinkDB

DBGET integrated database retrieval system