KEGG   ORTHOLOGY: K22091
Entry
K22091                      KO                                     
Symbol
OMT
Name
7'-O-demethylcephaeline/cephaeline O-methyltransferase [EC:2.1.1.395 2.1.1.396 2.1.1.-]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R11681  S-adenosyl-L-methionine:deacetylisoipecoside 6-O-methyltransferase
R11685  S-adenosyl-L-methionine:7'-O-demethylcephaeline 7'-O-methyltransferase
R11686  S-adenosyl-L-methionine:cephaeline 6'-O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K22091  OMT; 7'-O-demethylcephaeline/cephaeline O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.395  7'-O-demethylcephaeline methyltransferase
     K22091  OMT; 7'-O-demethylcephaeline/cephaeline O-methyltransferase
    2.1.1.396  cephaeline 6'-O-methyltransferase
     K22091  OMT; 7'-O-demethylcephaeline/cephaeline O-methyltransferase
Genes
CARB: 113728612 140035835
AG: BAI79243(OMT1) BAI79244(OMT2) BAI79245(OMT3) BAJ72588(OMT1)
Reference
PMID:20061395
  Authors
Nomura T, Kutchan TM
  Title
Three new O-methyltransferases are sufficient for all O-methylation reactions of ipecac alkaloid biosynthesis in root culture of Psychotria ipecacuanha.
  Journal
J Biol Chem 285:7722-38 (2010)
DOI:10.1074/jbc.M109.086157
  Sequence
[ag:BAI79243 BAI79244]
Reference
PMID:21228475
  Authors
Cheong BE, Takemura T, Yoshimatsu K, Sato F
  Title
Molecular cloning of an O-methyltransferase from adventitious roots of Carapichea ipecacuanha.
  Journal
Biosci Biotechnol Biochem 75:107-13 (2011)
DOI:10.1271/bbb.100605
  Sequence
[ag:BAJ72588]
LinkDB

KEGG   REACTION: R11681
Entry
R11681                      Reaction                               
Name
S-adenosyl-L-methionine:deacetylisoipecoside 6-O-methyltransferase
Definition
Deacetylisoipecoside + S-Adenosyl-L-methionine <=> 6-O-Methyldeacetylisoipecoside + S-Adenosyl-L-homocysteine
Equation
C07304 + C00019 <=> C21566 + C00021
Reaction class
RC00392  C07304_C21566
Enzyme
2.1.1.-
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R11681  Deacetylisoipecoside + S-Adenosyl-L-methionine <=> 6-O-Methyldeacetylisoipecoside + S-Adenosyl-L-homocysteine
Orthology
K22091  7'-O-demethylcephaeline/cephaeline O-methyltransferase [EC:2.1.1.395 2.1.1.396 2.1.1.-]
LinkDB

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