KEGG   ORTHOLOGY: K22799
Entry
K22799            Tight     KO                                     
Symbol
auaA
Name
2-methyl-4-hydroxyquinoline prenyltransferase [EC:2.5.1.-]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00848  Aurachin biosynthesis, anthranilate => aurachin A
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K22799  auaA; 2-methyl-4-hydroxyquinoline prenyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.-
     K22799  auaA; 2-methyl-4-hydroxyquinoline prenyltransferase
Other DBs
RN: R12050
Genes
AG: CAL48953(auaA)
Reference
PMID:21770425
  Authors
Pistorius D, Li Y, Mann S, Muller R
  Title
Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis.
  Journal
J Am Chem Soc 133:12362-5 (2011)
DOI:10.1021/ja203653w
  Sequence
[ag:CAL48953]
LinkDB

KEGG   REACTION: R12050
Entry
R12050                      Reaction                               
Definition
2-Methylquinolin-4-ol + trans,trans-Farnesyl diphosphate <=> Aurachin D + Diphosphate
Equation
C21873 + C00448 <=> C10641 + C00013
Enzyme
2.5.1.-
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00848  Aurachin biosynthesis, anthranilate => aurachin A
Orthology
K22799  2-methyl-4-hydroxyquinoline prenyltransferase [EC:2.5.1.-]
Reference
1  [PMID:17335090]
  Authors
Sandmann A, Dickschat J, Jenke-Kodama H, Kunze B, Dittmann E, Muller R
  Title
A Type II polyketide synthase from the gram-negative Bacterium Stigmatella aurantiaca is involved in Aurachin alkaloid biosynthesis.
  Journal
Angew Chem Int Ed Engl 46:2712-6 (2007)
DOI:10.1002/anie.200603513
LinkDB

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