| Entry |
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| Name |
ent-13-epi-manoyl oxide synthase;
SmKSL2;
ent-LDPP synthase
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
ent-8alpha-hydroxylabd-13-en-15-yl-diphosphate diphosphate-lyase (cyclizing, ent-13-epi-manoyl-oxide-forming)
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| Reaction(IUBMB) |
ent-8alpha-hydroxylabd-13-en-15-yl diphosphate = ent-13-epi-manoyl oxide + diphosphate [RN: R11851]
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| Reaction(KEGG) |
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| Substrate |
ent-8alpha-hydroxylabd-13-en-15-yl diphosphate [CPD: C21656]
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| Product |
ent-13-epi-manoyl oxide [CPD: C21714];
diphosphate [CPD: C00013]
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| Comment |
Isolated from the plant Salvia miltiorrhiza (red sage).
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| History |
EC 4.2.3.186 created 2017
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| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K22947 | ent-13-epi-manoyl oxide synthase |
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| Genes |
| SSPL: | 121774692 121777194 |
| SHIS: | 125207091 125207100 |
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| Reference |
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| Authors |
Cui G, Duan L, Jin B, Qian J, Xue Z, Shen G, Snyder JH, Song J, Chen S, Huang L, Peters RJ, Qi X |
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| Title |
Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.3.186 |
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| LinkDB |
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