KEGG   ORTHOLOGY: K23233
Entry
K23233                      KO                                     
Symbol
ODH1
Name
D-octopine dehydrogenase [EC:1.5.1.11]
Pathway
map00330  Arginine and proline metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K23233  ODH1; D-octopine dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.11  D-octopine dehydrogenase
     K23233  ODH1; D-octopine dehydrogenase
Other DBs
RN: R00562
GO: 0047830
Genes
GAE: 121375148 121375171 121375569 121375879
HRF: 124130929 124130932 124135646 124141222 124141236 124143581
HRJ: 124269418 124275434 124275436 124275497 124279633 124285795 124285908
CRG: 105331524 105331525 105331526 105331584 105342796
MYI: 110451252
PMAX: 117318100 117324891 117325339 117332653
MMER: 123524662 123525369 123525370 123525934
OSN: 115219799 115219972
AG: CAC36305(ODH1)
Reference
  Authors
Muller A, Janssen F, Grieshaber MK
  Title
Putative reaction mechanism of heterologously expressed octopine dehydrogenase from the great scallop, Pecten maximus (L).
  Journal
FEBS J 274:6329-39 (2007)
DOI:10.1111/j.1742-4658.2007.06151.x
  Sequence
LinkDB

KEGG   ORTHOLOGY: K24954
Entry
K24954                      KO                                     
Symbol
ooxA
Name
octopine oxidase subunit A
Pathway
map00330  Arginine and proline metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K24954  ooxA; octopine oxidase subunit A
Other DBs
RN: R12707
COG: COG0446
Genes
PHT: BLM14_26890
SMI: BN406_03690(ooxA1)
RHI: NGR_b06440(ooxA)
SFD: USDA257_c20480(ooxA)
SINO: SS05631_c18780
EAD: OV14_b0446(ooxA)
ATF: Ach5_51580(noxA)
RET: RHE_PF00358(ooxA)
REL: REMIM1_PF00554(ooxA)
RHN: AMJ98_PE00458(ooxA)
RHX: AMK02_PD00314(ooxA)
RHK: Kim5_PC00351(ooxA)
REZ: AMJ99_PD00458(ooxA)
SHZ: shn_16960
BOS: BSY19_923
AZC: AZC_1237
ALI: AZOLI_p20667(ooxA)
 » show all
Reference
PMID:8045881
  Authors
Zanker H, Lurz G, Langridge U, Langridge P, Kreusch D, Schroder J.
  Title
Octopine and nopaline oxidases from Ti plasmids of Agrobacterium tumefaciens: molecular analysis, relationship, and functional characterization.
  Journal
J Bacteriol 176:4511-7 (1994)
DOI:10.1128/jb.176.15.4511-4517.1994
  Sequence
LinkDB

KEGG   ORTHOLOGY: K24955
Entry
K24955                      KO                                     
Symbol
ooxB
Name
octopine oxidase subunit B
Pathway
map00330  Arginine and proline metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K24955  ooxB; octopine oxidase subunit B
Other DBs
RN: R12707
COG: COG0665
Genes
VEI: Veis_0204
PHT: BLM14_26900
KMN: HW532_08835
SMI: BN406_03688(ooxB1)
RHI: NGR_b06460(ooxB)
SFD: USDA257_c20470(ooxB)
SINO: SS05631_c18800
EAD: OV14_b0444(ooxB)
ATF: Ach5_51600(noxB)
RET: RHE_PF00357(ooxB)
RHN: AMJ98_PE00456(ooxB)
RHX: AMK02_PD00312(ooxB)
RHK: Kim5_PC00349(ooxB)
REZ: AMJ99_PD00456(ooxB)
SHZ: shn_16970
BARH: WN72_06880
BOS: BSY19_921
AZC: AZC_1235
ALI: AZOLI_p20665(ooxB)
ABS: AZOBR_p310237(ooxB)
 » show all
Reference
PMID:8045881
  Authors
Zanker H, Lurz G, Langridge U, Langridge P, Kreusch D, Schroder J.
  Title
Octopine and nopaline oxidases from Ti plasmids of Agrobacterium tumefaciens: molecular analysis, relationship, and functional characterization.
  Journal
J Bacteriol 176:4511-7 (1994)
DOI:10.1128/jb.176.15.4511-4517.1994
  Sequence
LinkDB

KEGG   ENZYME: 1.5.1.11
Entry
EC 1.5.1.11                 Enzyme                                 
Name
D-octopine dehydrogenase;
D-octopine synthase;
octopine dehydrogenase;
octopine:NAD+ oxidoreductase;
ODH;
2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)
Reaction(IUBMB)
N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH + H+ [RN:R00562]
Reaction(KEGG)
R00562
Substrate
N2-(D-1-carboxyethyl)-L-arginine [CPD:C04137];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
L-arginine [CPD:C00062];
pyruvate [CPD:C00022];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
In the reverse direction, acts also on L-ornithine, L-lysine and L-histidine.
History
EC 1.5.1.11 created 1972
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K23233  D-octopine dehydrogenase
Genes
GAE121375148 121375171 121375569 121375879
HRF124130929 124130932 124135646 124141222 124141236 124143581
HRJ124269418 124275434 124275436 124275497 124279633 124285795 124285908
CRG105331524 105331525 105331526 105331584 105342796
MYI110451252
PMAX117318100 117324891 117325339 117332653
MMER123524662 123525369 123525370 123525934
OSN115219799 115219972
Reference
1
  Authors
Kemp, J.D., Hack, E., Sutton, D.W. and El-Wakil, M.
  Title
Unusual amino acids and their relationship to tumorigenesis.
  Journal
Proc Int Conf Plant Pathol Bact 4th:183-188 (1979)
Reference
2  [PMID:4310628]
  Authors
van Thoai N, Huc C, Pho DB, Olomucki A.
  Title
[Octopine dehydrogenase. Purification and catalytic properties]
  Journal
Biochim Biophys Acta 191:46-57 (1969)
DOI:10.1016/0005-2744(69)90313-1
Other DBs
ExplorEnz - The Enzyme Database: 1.5.1.11
IUBMB Enzyme Nomenclature: 1.5.1.11
ExPASy - ENZYME nomenclature database: 1.5.1.11
BRENDA, the Enzyme Database: 1.5.1.11
CAS: 37256-27-2
LinkDB

KEGG   REACTION: R00562
Entry
R00562                      Reaction                               
Name
N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)
Definition
Octopine + NAD+ + H2O <=> L-Arginine + Pyruvate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00283  C00062_C04137
RC00581  C00022_C04137
Enzyme
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K23233  D-octopine dehydrogenase [EC:1.5.1.11]
Other DBs
RHEA: 16288
LinkDB

KEGG   REACTION: R12707
Entry
R12707                      Reaction                               
Definition
Octopine + H2O + Acceptor <=> L-Arginine + Pyruvate + Reduced acceptor
Equation
Comment
octopine oxidase
Reaction class
RC00283  C00062_C04137
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K24954  octopine oxidase subunit A
K24955  octopine oxidase subunit B
LinkDB

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