KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00902 Monoterpenoid biosynthesis
K23276 CYP72A224; 7-deoxyloganate 7-hydroxylase
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450
K23276 CYP72A224; 7-deoxyloganate 7-hydroxylase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.85 7-deoxyloganate 7-hydroxylase
K23276 CYP72A224; 7-deoxyloganate 7-hydroxylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, plant type
CYP72 family
K23276 CYP72A224; 7-deoxyloganate 7-hydroxylase
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
The enzyme, characterized from the plant Catharanthus roseus, is a cytochrome P-450 (heme-thiolate) enzyme. It catalyses a reaction in the pathway leading to biosynthesis of monoterpenoid indole alkaloids.
History
EC 1.14.14.85 created 2002 as EC 1.14.13.74, transferred 2018 to EC 1.14.14.85, modified 2018
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.85
R03556 Deoxyloganin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Loganin + [Oxidized NADPH---hemoprotein reductase] + H2O