| Entry |
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| Name |
indoleacetate decarboxylase;
IAD
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| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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| Sysname |
(1H-indol-3-yl)acetate carboxy-lyase (skatole-forming)
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| Reaction(IUBMB) |
(1H-indol-3-yl)acetate = skatole + CO2 [RN: R12303]
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| Reaction(KEGG) |
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| Substrate |
(1H-indol-3-yl)acetate [CPD: C00954]
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| Product |
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| Comment |
This glycyl radical enzyme has been isolate from a number of bacterial species. Skatole contributes to the characteristic smell of animal faeces.
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| History |
EC 4.1.1.115 created 2019
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| Pathway |
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| Orthology |
| K23384 | indoleacetate decarboxylase |
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| Genes |
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| Reference |
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| Authors |
Liu D, Wei Y, Liu X, Zhou Y, Jiang L, Yin J, Wang F, Hu Y, Nanjaraj Urs AN, Liu Y, Ang EL, Zhao S, Zhao H, Zhang Y |
|---|
| Title |
Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.1.1.115 |
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| LinkDB |
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