KEGG ORTHOLOGY: K23417

ORTHOLOGY: K23417

Entry

K23417                      KO

Symbol

SPINK1

Name

serine protease inhibitor Kazal-type 1

Disease

H00932

Tropical calcific pancreatitis

H00933

Hereditary pancreatitis

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K23417  SPINK1; serine protease inhibitor Kazal-type 1
Peptidases and inhibitors [BR:ko01002]
Peptidase inhibitors
  Family I1: Kazal family
   K23417  SPINK1; serine protease inhibitor Kazal-type 1

Other DBs

GO:

0004867

Genes

HSA:	6690(SPINK1)

PTR:	740785(SPINK1)

PPS:	100987866(SPINK1)

GGO:	101138697(SPINK1)

PON:	100450584(SPINK1)

PPYG:

129037495(SPINK1)

NLE:	100588071(SPINK1)

HMH:	116471680(SPINK1)

SSYN:

129485699(SPINK1)

MCC:	708951(SPINK1)

MCF:	102133189(SPINK1)

MTHB:

126956809

MNI:	105466910(SPINK1)

CSAB:

103244754(SPINK1)

CATY:

105589843(SPINK1)

PANU:

101025154(SPINK1)

TGE:	112626068(SPINK1)

MLEU:

105538954(SPINK1)

RRO:	104678154(SPINK1)

RBB:	108529912(SPINK1)

TFN:	117065655(SPINK1)

PTEH:

111552651(SPINK1)

CANG:

105504195(SPINK1)

CJC:	100402066(SPINK1)

SBQ:	101029909(SPINK1)

CIMI:

108290997(SPINK1)

ANAN:

105719933(SPINK1)

CSYR:

103253391(SPINK1)

MMUR:

105876506(SPINK1)

LCAT:

123638740(SPINK1)

PCOQ:

105821533(SPINK1)

OGA:	100946449(SPINK1)

MMU:	20730(Spink1)

MCAL:

110285146(Spink1)

MPAH:

110333522(Spink1)

RNO:	24833(Spink1) 266602(Spink1l)

MCOC:

116087115(Spink1)

ANU:	117701928 117719621 117719622 117719624

ASYL:

127663736(Spink1)

MUN:	110548761(Spink1)

CGE:	100754615(Spink1)

MAUA:

101839195(Spink1)

PROB:

127234212(Spink1)

PLEU:

114701586(Spink1)

MORG:

121442267 121453701

MFOT:

126494022

AAMP:

119815741(Spink1)

NGI:	103727397(Spink1)

HGL:	101704124(Spink1)

CPOC:

100719912(Spink1)

CCAN:

109674199(Spink1)

DORD:

105992602(Spink1)

DSP:	122118229(Spink1)

DMER:

138837477(Spink1)

PLOP:

125340184(Spink1)

NCAR:

124987400

MMMA:

107135613(Spink1)

ITI:	101972666(Spink1)

OCU:

103347911

TUP:	102490155(SPINK1)

GVR:	103598655(SPINK1)

CFA:	608433(SPINK1)

CLUD:

112660245(SPINK1)

VVP:	112907646(SPINK1)

VLG:	121496662(SPINK1)

NPO:	129513918(SPINK1)

AML:	105234509(SPINK1)

UMR:	103663684(SPINK1)

UAH:	113254947(SPINK1)

UAR:	123790572(SPINK1)

ELK:

111156855

LLV:

125100300

MPUF:

101675158(SPINK1)

MNP:	132027902(SPINK1)

MLK:	131831381(SPINK1)

ORO:	101381628(SPINK1)

EJU:	114220962(SPINK1)

ZCA:	113929498(SPINK1)

MLX:	118016785(SPINK1)

NSU:	110591243(SPINK1)

LWW:	102747466(SPINK1)

FCA:	101085948(SPINK1)

PYU:	121016028(SPINK1)

PCOO:

112861508(SPINK1)

PBG:	122488761(SPINK1)

PVIV:

125172665(SPINK1)

LRUF:

124528881

LGF:	123605727(SPINK1)

AJU:

106984949

PTG:	102950162(SPINK1)

PPAD:

109246322(SPINK1)

PUC:

125935617

PLEZ:

122219901(SPINK1)

HHV:	120239951(SPINK1)

BTA:	574092(SPINK1)

BOM:	102266339(SPINK1)

BBUB:

102397682(SPINK1)

BBIS:

104996273(SPINK1)

CHX:	102173184(SPINK1)

OAS:	101115618(SPINK1)

BTAX:

128051690(SPINK1)

CSUM:

138086468(SPINK1)

ODA:	120863488(SPINK1)

CCAD:

122439199(SPINK1)

MREE:

136168361(SPINK1)

OVR:	110135898(SPINK1)

MBEZ:

129559517(SPINK1)

SSC:	100622575(SPINK1)

CFR:	102515301(SPINK1)

CBAI:

105072615(SPINK1)

CDK:	105097756(SPINK1)

VPC:	102529489(SPINK1)

BACU:

103005703(SPINK1)

BMUS:

118893439(SPINK1)

LVE:	103071545(SPINK1)

OOR:	101278354(SPINK1)

LALB:

132518519(SPINK1)

GMF:	115847492(SPINK1)

DDP:	132422022(SPINK1)

DLE:

111183175

PCAD:

102991065(SPINK1)

PSIU:

116751857(SPINK1)

PPHC:

136121064

NASI:

112395196

ECB:	100630883(SPINK1)

EPZ:	103552899(SPINK1)

EAI:	106839847(SPINK1)

MYB:	102243392(SPINK1)

MYD:	102774533(SPINK1)

MMYO:

118659155(SPINK1)

MLF:	102439898(SPINK1)

MDT:	132235816(SPINK1)

MYUM:

139011626(SPINK1)

PKL:	118711674(SPINK1)

MNA:	107541900(SPINK1)

DRO:	112319713(SPINK1)

SHON:

118986223

AJM:

119061354

PDIC:

114510070(SPINK1)

PHAS:

123810966(SPINK1)

MMF:	118616404(SPINK1)

PPAM:

129066393(SPINK1)

RFQ:	117016860(SPINK1)

PALE:

102881090(SPINK1)

PGIG:

120581163(SPINK1)

PVP:	105308122(SPINK1)

RAY:	107513532(SPINK1)

MJV:	108387917(SPINK1)

TOD:	119242708(SPINK1)

SARA:

101556207(SPINK1)

SFUM:

130033106(SPINK1)

LAV:	100662068(SPINK1)

TMU:

101345485

DNM:	101427461(SPINK1)

MDO:	103091878 103104157 103104500 103104662 103104981 103105477 103105631 103105989 103106275 103106743

GAS:	123235510 123235512 123235513 123235515 123235518

SHR:	111721466(SPINK1)

PCW:	110216749 110216751 110216752(SPINK1)

TVP:

118844491

PBRV:

138172480(SPINK1)

OAA:

TACU:

GGA:

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

ETL:

ZAB:

ZLE:

SVG:

MMEA:

HRT:

SATI:

CCIC:

FPG:	106112112(SPINK1)

FCH:	106631025(SPINK1)

NNT:	104408506(SPINK1)

SHAB:

115615564

ACUN:

113485465

TALA:

116964925(SPINK1)

ACHC:

115334398(SPINK1)

AGEN:

126050990

HHAR:

128154888(SPINK1)

GCL:

127022182

PPUS:

135185302

BRHI:

104499093

EGZ:	118452810(SPINK1)

NNI:

104018978

PCRI:

104038033(SPINK1)

PCAO:

104048651(SPINK1)

PADL:

103924923(SPINK1)

AFOR:

103904536(SPINK1)

FGA:	104079755(SPINK1)

GSTE:

104253386(SPINK1)

CBOY:

140656849(SPINK1)

CLV:

CNIC:

CUCA:

ACAR:

CVF:	104293937(SPINK1)

RTD:	128916300(SPINK1)

CRID:

134522163(SPINK1)

AAM:	106485288(SPINK1)

AROW:

NPD:

DNE:

ASN:

AMJ:

CPOO:

GGN:

CMY:

DCC:

TST:	117882306(SPINK1)

MRV:

ACS:

ASAO:

PVT:

SUND:

PMUA:

PRAF:

ZVI:

EMC:

XLA:	108710581 108712495

XTR:

RTEM:

ACAT:

BBUF:

BGAR:

PWL:	138247279 138247288

GSH:

117351513

DRE:	100334344(si:ch211-195b11.3)

SRX:

107740183

SANH:

107680339 107680962

SGH:	107554830 107593236

CAUA:

113075405 113078524 113114135

CGIB:

127971569 128027457

PTET:

122358111(si:ch211-195b11.3)

LROH:

127176367(si:ch211-195b11.3)

OMC:	131552982(si:ch211-195b11.3)

PPRM:

120466325(si:ch211-195b11.3)

RKG:	130103951(si:ch211-195b11.3)

MAMB:

125258685(si:ch211-195b11.3)

CIDE:

127494789(si:ch211-195b11.3)

CERY:

137021530(si:ch211-195b11.3)

MASI:

127412991 127418258

TROS:

130563488(si:ch211-195b11.3)

TDW:	130437631(si:ch211-195b11.3)

PDAB:

135758197

IPU:	108266920 108277718

IFU:

PHYP:

SMEO:

TFD:

TVC:

CGAR:

128523976 128532994(si:ch211-195b11.3)

NGRA:

132891470

TRN:

134334749

AMEX:

103037229(si:ch211-195b11.3) 125803812

EEE:

113590583

CHAR:

105908150(si:ch211-195b11.3)

SPIL:

134068454(si:ch211-195b11.3) 134071645

TRU:

TFS:

LCO:

TBEN:

CGOB:

PGEO:

EMAC:

ELY:

EFO:

SLUC:

ECRA:

ESP:	116670684 116685998

PFLV:

GAT:

PPUG:

AFB:

CVE:

MSAM:

SCHU:

CUD:	121516009(si:ch211-195b11.3)

ALAT:

MZE:

ONL:

OAU:

OLA:

OML:

PPRL:

CTUL:

GMU:

NFU:

KMR:

ALIM:

CSEM:

SSEN:

SSOE:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

PEE:

PTAO:

BPEC:

ENY:

MALB:

109966464(spink1)

SASA:

STRU:

OTW:

OMY:

OGO:

ONE:

OKI:

OKE:

OMM:

OCLA:

SALP:

SNH:

CCLU:

123492844(si:ch211-195b11.3)

ELS:

OEP:

SFM:

PKI:

AANG:

118222825(si:ch211-195b11.3) 118223952 118223954

CCOG:

133123142 133123204

PSPA:

121308021

PSEX:

120542486(si:ch211-195b11.3)

LCM:

CMK:

LERI:

HAKA:

SCLV:

ACOZ:

AARA:

AMER:

ASTE:

AMOU:

CPII:

TPRE:

CCIN:

EFOR:

HAXR:

MSEX:

AAGE:

OFU:	114353429 114360417

CFUM:

141440473

CSEC:

111873797

PAME:

138697744 138700478 138700479 138700480

IEL:

124155444

PCHN:

125027339 125027636 125032023

PMEO:

129588398

BGT:	106065472 106073614

CVN:

MMER:

RPHI:

DPOL:

MAEA:

128230029 128232501 128233052

» show all

Reference

PMID:3877508

Authors

Yamamoto T, Nakamura Y, Nishide J, Emi M, Ogawa M, Mori T, Matsubara K

Title

Molecular cloning and nucleotide sequence of human pancreatic secretory trypsin inhibitor (PSTI) cDNA.

Journal

Biochem Biophys Res Commun 132:605-12 (1985)
DOI:10.1016/0006-291X(85)91176-3

Sequence

[hsa:6690]

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