KEGG   ORTHOLOGY: K23672
Entry
K23672            Tight     KO                                     
Symbol
besA
Name
L-propargylglycine--L-glutamate ligase [EC:6.3.2.-]
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00906  Ethynylserine biosynthesis, lysine => ethynylserine
Reaction
R12410  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    K23672  besA; L-propargylglycine--L-glutamate ligase
Other DBs
COG: COG2232 COG4868
Genes
SCT: SCAT_p1045
SCY: SCATT_p06910
Reference
PMID:30867596
  Authors
Marchand JA, Neugebauer ME, Ing MC, Lin CI, Pelton JG, Chang MCY
  Title
Discovery of a pathway for terminal-alkyne amino acid biosynthesis.
  Journal
Nature 567:420-424 (2019)
DOI:10.1038/s41586-019-1020-y
  Sequence
[scy:SCATT_p06910]
LinkDB

KEGG   REACTION: R12410
Entry
R12410                      Reaction                               
Definition
L-Propargylglycine + L-Glutamate <=> gamma-L-Glutamyl-L-propargylglycine
Equation
C22138 + C00025 <=> C22139
Comment
unclear reaction
Reaction class
RC00064  C22138_C22139
RC00090  C00025_C22139
Enzyme
6.3.2.-
Pathway
rn00997  Biosynthesis of various other secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00906  Ethynylserine biosynthesis, lysine => ethynylserine
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.-
     R12410  L-Propargylglycine + L-Glutamate <=> gamma-L-Glutamyl-L-propargylglycine
Orthology
K23672  L-propargylglycine--L-glutamate ligase [EC:6.3.2.-]
Other DBs
RHEA: 59899
LinkDB

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