KEGG   ORTHOLOGY: K24042
Entry
K24042                      KO                                     
Symbol
yitJ
Name
methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Pathway
map00270  Cysteine and methionine metabolism
map00450  Selenocompound metabolism
map00670  One carbon pool by folate
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01230  Biosynthesis of amino acids
Module
M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Reaction
R00946  5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
R07168  5-methyltetrahydrofolate:NAD+ oxidoreductase
R09365  5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K24042  yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    K24042  yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K24042  yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     K24042  yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     K24042  yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH)
Other DBs
COG: COG0646 COG0685
GO: 0008705 0106312
Genes
SDO: SD1155_04600
GSU: GSU2974(metF-2)
GSK: KN400_2916(metF-2)
GME: Gmet_0504(metF-2)
GPI: GPICK_02780
GAO: A2G06_13980
GBZ: JZM60_08150
GEM: GM21_0627
GEB: GM18_3740
GEF: FO488_00090
GEV: GSVR_00620(metF-2)
GUR: Gura_0708
GEO: Geob_0913(metF-2)
GBM: Gbem_0613(metF-2)
GBN: GEOBRER4_06190(metF-2)
PCA: Pcar_0238(metF-2)
PPD: Ppro_0283
DEU: DBW_0663
DVE: DESUT3_04310(metF-2)
DEP: AOP6_2715(metF-2)
DES: DSOUD_3430(metF-2)
DFL: DFE_1625
DBA: Dbac_0626
DDU: GF1_05580(metF-2)
SAT: SYN_00176
SCL: sce8634
HOH: Hoch_4784
BSU: BSU11010(yitJ)
BSL: A7A1_0917
BSH: BSU6051_11010(yitJ)
BSUT: BSUB_01198(yitJ)
BSUL: BSUA_01198(yitJ)
BSUS: Q433_06215
BSO: BSNT_07540(yitJ)
BSQ: B657_11010(samT)
BSX: C663_1125(yitJ)
BSS: BSUW23_05580(yitJ)
BLI: BL01307(yitJ)
BLD: BLi01193(yitJ)
BLH: BaLi_c13250(yitJ)
BAQ: BACAU_1062(yitJ)
BYA: BANAU_1008(yitJ)
BAMP: B938_05335
BQY: MUS_1139(yitJ)
BAML: BAM5036_1002(yitJ)
BAMA: RBAU_1062(samT)
BAMN: BASU_1041(samT)
BAMB: BAPNAU_2694(yitJ)
BAMT: AJ82_06195
BAMY: V529_10470(yitJ)
BMP: NG74_01111(yitJ)
BAO: BAMF_1175(yitJ)
BAZ: BAMTA208_05120(yitJ)
BQL: LL3_01179(yitJ)
BXH: BAXH7_01074(yitJ)
BAMI: KSO_014340
BAMF: U722_05610
BSON: S101395_03649(mmuM)
BMOJ: HC660_11560(samT)
BSTR: QI003_05935(samT)
BAN: BA_4479
BAR: GBAA_4479
BAT: BAS4157
BAI: BAA_4496
BANT: A16_44740
BANR: A16R_45300
BANS: BAPAT_4297
BANV: DJ46_3161
BCE: BC4251
BCA: BCE_4333
BCZ: BCE33L4006(metE)
BCQ: BCQ_4039(metE)
BCX: BCA_4364
BAL: BACI_c42200(metE2)
BNC: BCN_4167
BCF: bcf_21155
BCER: BCK_13900
BTK: BT9727_3996(metE)
BTL: BALH_3851(metE)
BTT: HD73_4559
BTHI: BTK_22460
BTM: MC28_3547
BTG: BTB_c43980(yitJ)
BTI: BTG_27860
BTW: BF38_12
BWW: bwei_0681(metF)
BMYO: BG05_1763
BMYC: DJ92_1359
BPU: BPUM_1027
BPUM: BW16_05885
BPUS: UP12_05490
BMET: BMMGA3_08610(yitJ)
BGY: BGLY_1222(yitJ)
BAER: BAE_13045
BFD: NCTC4823_02001(yitJ)
BJS: MY9_1199
BACW: QR42_05325
BACP: SB24_04355
BACB: OY17_08210
BACO: OXB_0745
BACY: QF06_04440
BACL: BS34A_12150(yitJ)
BALM: BsLM_1146
BASB: M662_01465
BMQ: BMQ_1294(yitJ)
BMD: BMD_1274(yitJ)
BMH: BMWSH_3939(yitJ)
BMEG: BG04_3589
BEO: BEH_04990
BHA: BH1629
BKW: BkAM31D_10855(yitJ)
BCL: ABC1868
BPF: BpOF4_15300(yitJ)
GKA: GK0717
GTN: GTNG_0622
GGH: GHH_c06660(yitJ)
GEA: GARCT_00713(yitJ)
PCAL: BV455_01044(yitJ_1) BV455_02252(yitJ_2)
PARG: PspKH34_30100(yitJ)
AFL: Aflv_2165
AAMY: GFC30_1086
AAYD: B379_03295
LSP: Bsph_0175
LYP: MTP04_34720(yitJ)
HLI: HLI_10240
VPN: A21D_01129(yitJ)
PASA: BAOM_3193(mmuM)
BLEN: NCTC4824_01893(yitJ)
BAG: Bcoa_0890
BCOA: BF29_2838
BBEV: BBEV_2857(yitJ-2)
SAU: SA0345
SAV: SAV0357
SAW: SAHV_0354
SAM: MW0333
SAS: SAS0333
SAR: SAR0354
SAC: SACOL0429
SAE: NWMN_0349(metH)
SAD: SAAV_0325
SUK: SAA6008_00334(metH)
SUC: ECTR2_318
SUZ: MS7_0347
SUG: SAPIG0437
SAUA: SAAG_00845
SAUE: RSAU_000302(metE2)
SAUS: SA40_0313
SAUU: SA957_0328
SAUG: SA268_0326
SAUF: X998_0414
SAB: SAB0307c(metE2)
SAUB: C248_0413
SAUM: BN843_3630
SAUC: CA347_370
SAUR: SABB_02272(metH)
SAUI: AZ30_01830
SAUD: CH52_03940
SAMS: NI36_01695
SER: SERP0035
SEP: SE_2381
SEPP: SEB_02376
SEPS: DP17_1438
SHA: SH2637
SHH: ShL2_02433(metH)
SSP: SSP2415
SCA: SCA_0013(metH)
SDT: SPSE_2483
SDP: NCTC12225_02683(metH)
SPAS: STP1_1469
SCAP: AYP1020_2114(yitJ)
SSCH: LH95_11480
SSCZ: RN70_12185
SAGQ: EP23_10200
SARL: SAP2_24830
SPIC: SAMEA4384060_2512(metH)
SSH: NCTC13712_00303(metH)
SSIM: SAMEA4384339_0314(metH)
STAP: AOB58_1732
SSTE: SAMEA4384403_2481(metH)
LMO: lmo1678
LMOE: BN418_1987
LMOB: BN419_1991
LMOD: LMON_1745
LMOW: AX10_02485
LMR: LMR479A_1777(samT)
LMOM: IJ09_01585
LMOG: BN389_17060(yitJ)
LMP: MUO_08630
LMOX: AX24_05960
LMQ: LMM7_1767(mmuM)
LMS: LMLG_1203
LMOK: CQ02_08605
LIN: lin1786
LWE: lwe1696
LSG: lse_1646
LIV: LIV_1653
LGZ: NCTC10812_01198(metH)
GMO: NCTC11323_01386(metH)
GHA: NCTC10459_01407(metH)
BLR: BRLA_c015030(yitJ)
PPY: PPE_02925
PPM: PPSC2_15475(yitJ)
PPO: PPM_3138(yitJ)
PPOL: X809_31860
PPOY: RE92_21240
PMW: B2K_27170
PLV: ERIC2_c22790(yitJ)
PSAB: PSAB_11080
PRI: PRIO_2929(yitJ)
PSWU: SY83_15620
PBK: Back11_09830(yitJ)
PALO: E6C60_1641
PKP: SK3146_06539(yitJ)
ASOC: CB4_00810(yitJ)
COHN: KCTCHS21_39340(yitJ)
AAC: Aaci_1583
AAD: TC41_1476(mmuM)
SIV: SSIL_0446
JEO: JMA_11950
KUR: ASO14_347
KZO: NCTC404_01216(metH_1)
PABS: JIR001_28420(yitJ)
SAG: SAG2048
SAN: gbs2004
SAK: SAK_1987
SGC: A964_1896(mmuM)
SAGM: BSA_20370
SAGI: MSA_21060
SAGP: V193_08800
SAGC: DN94_08800
SAGE: EN72_10735
SAGG: EN73_09795
SAGN: W903_1954
SMU: SMU_874
SMJ: SMULJ23_1139(yitJ)
SMUA: SMUFR_0762(mmuM)
SGG: SGGBAA2069_c13040(yitJ)
SGT: SGGB_1309(yitJ)
STB: SGPB_1218(yitJ)
SMN: SMA_1241
SIF: Sinf_1133
SLU: KE3_1195
STRG: SRT_12720
SFER: NCTC12278_01082(yitJ)
LPL: lp_1374
LPJ: JDM1_1153(metH)
LPS: LPST_C1102(metH)
LPZ: Lp16_1054
CML: BN424_1092(yitJ)
CAC: CA_C0291
CAE: SMB_G0297
CAY: CEA_G0300
CBE: Cbei_1828
CBZ: Cbs_1828
CBEI: LF65_01988
CKL: CKL_1762(metH2)
CKR: CKR_1635
CRW: CROST_005790(yitJ)
CFB: CLFE_042750(yitJ)
CAUN: CLAUR_024270(yitJ)
CNN: CNEO_2392
CCE: Ccel_2474
CCEL: CCDG5_1402
FPR: FP2_27030
FPA: FPR_04840
SGY: Sgly_2859
DRM: Dred_1750
TMR: Tmar_1626
SAY: TPY_2937(mmuM)
HFV: R50_2705
BPRS: CK3_01590
CCT: CC1_34080
EHL: EHLA_1291
LBX: lbkm_2709
CSC: Csac_1165
ATE: Athe_0325
CDIA: CaldiYA01_20920(metF-2)
LPIL: LIP_2531
PDX: Psed_2107
PAUT: Pdca_65210(metF-2)
PFLA: Pflav_021240(metF-2)
RXY: Rxyl_0843
HAU: Haur_3632
ATM: ANT_11950
KBB: ccbrp13_09160(metF-2)
TTR: Tter_1187
TRO: trd_1049
MIN: Minf_1622(metF)
MKC: kam1_729
MFH: MFUM_0880(yitJ)
MCAO: IT6_09245
MEAP: MTHMO_1325(yitJ)
TTF: THTE_0698
PBU: L21SP3_00048(yitJ_1)
PBP: STSP1_00913(yitJ_2)
PBAS: SMSP2_02903(yitJ_3)
ALUS: STSP2_00682(yitJ_1)
ACA: ACP_1004
SUS: Acid_7115
ABAC: LuPra_03023(yitJ_1)
LUB: TBR22_A21070(metF-2)
GEX: GETHOR_24570(metF-2)
MSIL: METEAL_02160(metF-2)
MSEA: METESE_02160(metF-2)
HABY: HLVA_07750
GAU: GAU_0558
GBA: J421_2469
 » show all
Reference
  Authors
Grundy FJ, Henkin TM
  Title
The S box regulon: a new global transcription termination control system for methionine and cysteine biosynthesis genes in gram-positive bacteria.
  Journal
Mol Microbiol 30:737-49 (1998)
DOI:10.1046/j.1365-2958.1998.01105.x
  Sequence
[bsu:BSU11010]
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