Entry
Name
UDP-N-acetyl-L-fucosamine synthase;
WbjD;
Cap5G
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase
Reaction(IUBMB)
UDP-2-acetamido-2,6-dideoxy-beta-L-talose = UDP-N-acetyl-beta-L-fucosamine [RN:
R10676 ]
Reaction(KEGG)
Substrate
UDP-2-acetamido-2,6-dideoxy-beta-L-talose [CPD:
C20768 ]
Product
UDP-N-acetyl-beta-L-fucosamine [CPD:
C20774 ]
Comment
Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Involved in bacterial polysaccharide biosynthesis.
History
EC 5.1.3.28 created 2014
Pathway
ec00541 O-Antigen nucleotide sugar biosynthesis
Orthology
K24258 UDP-N-acetyl-L-fucosamine synthase
Genes
ECOO : ECRM13514_2752(fnlC)
ECOH : ECRM13516_2620(fnlC)
CIE : AN232_13740 AN232_31065
PDAG : 4362423_00267(wbjD)
PAEB : NCGM1900_3149(wbjD)
PTRT : HU722_0009240(wecB)
GAI : IMCC3135_22515(wbpI)
AALK : LGT41_0010480(wecB)
AMYT : AMYT_0883 AMYT_0912
BFD : NCTC4823_03154(mnaA_3)
SAA : SAUSA300_0158(cap5G)
SUJ : SAA6159_00139(cap8G)
SUK : SAA6008_00133(cap5G)
SUX : SAEMRSA15_01210(capG)
SUF : SARLGA251_01290(capG)
SAUT : SAI1T1_2001100(capG)
SAUJ : SAI2T2_1001100(capG)
SAUK : SAI3T3_1001100(capG)
SAUQ : SAI4T8_1001100(capG)
SAUV : SAI7S6_1001100(capG)
SAUW : SAI5S5_1001090(capG)
SAUX : SAI6T6_1001100(capG)
SAUY : SAI8T7_1001100(capG)
SSH : NCTC13712_00110(mnaA_1)
LGZ : NCTC10812_01729(mnaA_1)
EAP : KB235_04670(wecB) KB235_04835(wecB)
JAR : G7057_08185(wecB) G7057_08370(wecB)
CGEL : psyc5s11_50940(fnlC)
ACEL : acsn021_22610(capG)
ACHT : bsdcttw_26870(capG)
TSF : NQ543_04010(wecB) NQ543_06825(wecB) NQ543_07985(wecB)
AAXA : NCTC10138_00338(mnaA)
DCO : SAMEA4475696_2249(mnaA)
MSAG : GCM10017556_43860(rffE)
ACTR : Asp14428_57020(rffE)
OBG : Verru16b_02064(wbpI)
PBU : L21SP3_00952(wbpI_1)
CPOR : BED41_13420 BED41_15225
FSU : Fisuc_2681 Fisuc_2695
BTHO : Btheta7330_02109(wbpI_2) Btheta7330_02997(wbpI_4)
BFG : BF638R_1090 BF638R_1879
BFB : VU15_04780 VU15_07840
BCEL : BcellWH2_04979(wbpI_2)
BFE : K6V30_14850 K6V30_24435
PGOL : K6V26_10515(wecB) K6V26_11945(wecB)
RBC : BN938_0768 BN938_1958
CGLE : NCTC11432_02308(mnaA)
CTAI : NCTC12078_01303(mnaA)
CTAK : 4412677_01079(mnaA)
CSAL : NBC122_00351(wbpI_1) NBC122_02874(wbpI_2)
CJG : NCTC13459_02734(mnaA)
CANT : NCTC13489_01521(mnaA)
» show all
Taxonomy
Reference
Authors
Kneidinger B, O'Riordan K, Li J, Brisson JR, Lee JC, Lam JS
Title
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
Journal
Reference
Authors
Mulrooney EF, Poon KK, McNally DJ, Brisson JR, Lam JS
Title
Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.28
ExPASy - ENZYME nomenclature database: 5.1.3.28
LinkDB
All DBs