KEGG   ORTHOLOGY: K24304
Entry
K24304                      KO                                     
Symbol
lea5
Name
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose 2-epimerase
Pathway
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Reaction
R12558  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K24304  lea5; UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose 2-epimerase
Other DBs
COG: COG0381
Genes
VVU: VV1_0807
VVM: VVMO6_02803
VHA: VIBHAR_00671
VCA: M892_09495
SMAY: K0H60_06700(neuC)
TALZ: RPMA_09940(neuC)
THAI: IT893_15830(neuC)
TTB: MACH01_31170(legG)
THGO: M9H61_17520(neuC)
SSEI: FJR45_00980(neuC)
PSYF: N1030_14205(neuC)
DBK: DGMP_13520
BBAE: FRD01_15940(neuC)
AHAL: FTX54_015200(neuC)
BREH: HP435_26100(neuC)
OCW: OW730_17310(neuC)
TEB: T8CH_0144(legG)
HPRF: HLPR_26780(neuC)
AHQ: NMU03_10495(neuC)
BREM: PSR63_07870(neuC)
GAW: V144x_39880(legG)
ANF: AQPE_0357
SLAS: L2B55_03435(neuC)
EMAI: KZP23_21775(neuC)
MARP: QYS47_27750(neuC)
PPEC: H9W90_01220(neuC)
NVA: G3M78_01135(neuC)
AG: ADJ19197(lea5)
 » show all
Reference
PMID:20510395
  Authors
Li X, Perepelov AV, Wang Q, Senchenkova SN, Liu B, Shevelev SD, Guo X, Shashkov AS, Chen W, Wang L, Knirel YA
  Title
Structural and genetic characterization of the O-antigen of Escherichia coli O161 containing a derivative of a higher acidic diamino sugar, legionaminic acid.
  Journal
Carbohydr Res 345:1581-7 (2010)
DOI:10.1016/j.carres.2010.04.008
  Sequence
[ag:ADJ19197]
Reference
PMID:30315110
  Authors
McDonald ND, DeMeester KE, Lewis AL, Grimes CL, Boyd EF
  Title
Structural and functional characterization of a modified legionaminic acid involved in glycosylation of a bacterial lipopolysaccharide.
  Journal
J Biol Chem 293:19113-19126 (2018)
DOI:10.1074/jbc.RA118.004966
LinkDB

KEGG   REACTION: R12558
Entry
R12558                      Reaction                               
Definition
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose
Equation
C22247 <=> C22248
Comment
2-epimerase
Reaction class
RC00290  C22247_C22248
Enzyme
5.1.3.-
Pathway
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 5. Isomerase reactions
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.-
     R12558  UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose
Orthology
K24304  UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose 2-epimerase
LinkDB

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