KEGG   ORTHOLOGY: K25315
Entry
K25315                      KO                                     
Symbol
AFKP80
Name
arabinokinase / fucokinase / arabinose-1-phosphate guanylyltransferase / fucose-1-phosphate guanylyltransferase [EC:2.7.1.- 2.7.7.- 2.7.1.52 2.7.7.30]
Pathway
map00520  Amino sugar and nucleotide sugar metabolism
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Reaction
R01951  GTP:beta-L-fucose-1-phosphate guanylyltransferase
R03161  ATP:L-fucose 1-phosphotransferase
R12824  ATP:D-arabinose 1-phosphotransferase
R12825  GTP:alpha-D-arabinopyranose-1-phosphate guanylyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    K25315  AFKP80; arabinokinase / fucokinase / arabinose-1-phosphate guanylyltransferase / fucose-1-phosphate guanylyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.52  fucokinase
     K25315  AFKP80; arabinokinase / fucokinase / arabinose-1-phosphate guanylyltransferase / fucose-1-phosphate guanylyltransferase
   2.7.7  Nucleotidyltransferases
    2.7.7.30  fucose-1-phosphate guanylyltransferase
     K25315  AFKP80; arabinokinase / fucokinase / arabinose-1-phosphate guanylyltransferase / fucose-1-phosphate guanylyltransferase
Other DBs
GO: 0050201 0047341
Genes
LMA: LMJF_16_0440 LMJF_16_0480
LIF: LINJ_16_0450 LINJ_16_0490
LDO: LDBPK_160450
LMI: LMXM_16_0440 LMXM_16_0480
LMAT: 92515636(LSCM1_05678)
LBZ: LBRM_16_0500
LPAN: LPMP_160480
LOI: 92361452(LSCM4_05579)
LEIN: 94189632(JIQ42_06013)
PHET: 94291289(JKF63_05244)
Reference
  Authors
Guo H, Novozhilova NM, Bandini G, Turco SJ, Ferguson MAJ, Beverley SM.
  Title
Genetic metabolic complementation establishes a requirement for GDP-fucose in Leishmania.
  Journal
J Biol Chem 292:10696-10708 (2017)
DOI:10.1074/jbc.M117.778480
  Sequence
LinkDB

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