KEGG   ORTHOLOGY: K25497
Entry
K25497                      KO                                     
Symbol
bzaC
Name
5-hydroxybenzimidazole methyltransferase [EC:2.1.1.-]
Pathway
map00860  Porphyrin metabolism
map01100  Metabolic pathways
Reaction
R12854  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K25497  bzaC; 5-hydroxybenzimidazole methyltransferase
Other DBs
COG: COG2890 COG5423
Genes
GEV: GSVR_36250
DAT: HRM2_15660
DML: Dmul_26770
DEK: DSLASN_49310
CACE: CACET_c19180
CFM: BJL90_15675
DOR: Desor_2488
FWA: DCMF_02590
TJR: TherJR_0547
DGI: Desgi_4254
ELM: ELI_4218
EMT: CPZ25_011290
ELIM: B2M23_05575
AWO: Awo_c14610
AWI: CHL1_000342 CHL1_002407
TPZ: Tph_c05610
MTA: Moth_1720
MTHO: MOTHE_c17290(tcmN)
MTHZ: MOTHA_c18120(tcmN)
CALK: HUE98_02170
DFO: Dform_00445
 » show all
Reference
PMID:26246619
  Authors
Hazra AB, Han AW, Mehta AP, Mok KC, Osadchiy V, Begley TP, Taga ME
  Title
Anaerobic biosynthesis of the lower ligand of vitamin B12.
  Journal
Proc Natl Acad Sci U S A 112:10792-7 (2015)
DOI:10.1073/pnas.1509132112
  Sequence
[elm:ELI_4218]
LinkDB

KEGG   REACTION: R12854
Entry
R12854                      Reaction                               
Definition
S-Adenosyl-L-methionine + 5-Hydroxybenzimidazole <=> S-Adenosyl-L-homocysteine + 5-Methoxybenzimidazole
Equation
C00019 + C21764 <=> C00021 + C22450
Comment
SAM-dependent methyltransferase
Reaction class
RC00392  C21764_C22450
Enzyme
2.1.1.-
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R12854  S-Adenosyl-L-methionine + 5-Hydroxybenzimidazole <=> S-Adenosyl-L-homocysteine + 5-Methoxybenzimidazole
Orthology
K25497  5-hydroxybenzimidazole methyltransferase [EC:2.1.1.-]
LinkDB

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