KEGG   ORTHOLOGY: K26211
Entry
K26211                      KO                                     
Symbol
K26211
Name
guanosine phosphorylase [EC:2.4.2.15]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01232  Nucleotide metabolism
Module
M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate
Reaction
R02147  guanosine:phosphate alpha-D-ribosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K26211  K26211; guanosine phosphorylase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.15  guanosine phosphorylase
     K26211  K26211; guanosine phosphorylase
Other DBs
COG: COG0005
GO: 0047975
Genes
SLOM: PXH66_14350
AAQW: K1X11_021490
TOB: V4D31_06360(mtnP)
TAUT: V4D30_01725(mtnP)
NVA: G3M78_03720
BACN: GNK04_07020
ALKG: MOJ78_01200
NCJ: MCACP_10560(mtnP_2)
BACG: D2962_00915
TIZ: RBU61_10015
SPOK: ACFWUA_01985
LEIZ: IT072_20595
FSH: Q2T83_03560
PFU: PF0853
PFI: PFC_03460
PHO: PH1143(PH1143)
PAB: PAB1659
PYN: PNA2_1750
PYA: PYCH_04740
PYS: Py04_1066
PYC: TQ32_02700
TKO: TK1482
TON: TON_0128
TGA: TGAM_1953(mtaP-2)
TSI: TSIB_1419
TBA: TERMP_00252
THE: GQS_04600
THA: TAM4_95
THM: CL1_0573
TLT: OCC_03713
THS: TES1_0338
TNU: BD01_2216
TEU: TEU_05410
TGY: X802_02715
THV: ADU37_CDS15240
TCH: CHITON_0993
TPEP: A0127_07785
TPIE: A7C91_06585
TGG: A3K92_01065
TCE: A3L02_00285
TBS: A3L01_01345
THH: CDI07_01320(mtnP)
TSL: A3L11_05085
TTD: A3L14_02800
TPRF: A3L09_02815
TRL: A3L10_05235
TPAF: A3L08_04350
THY: A3L12_00855
TIC: FH039_03195(mtnP)
TCQ: TIRI35C_0489
THEM: FPV09_06005(mtnP)
THEI: K1720_10300(mtnP)
TAGG: NF865_04470(mtnP)
PPAC: PAP_07050
KCR: Kcr_1502
 » show all
Reference
PMID:25822915
  Authors
Aono R, Sato T, Imanaka T, Atomi H
  Title
A pentose bisphosphate pathway for nucleoside degradation in Archaea.
  Journal
Nat Chem Biol 11:355-60 (2015)
DOI:10.1038/nchembio.1786
  Sequence
[tko:TK1482]
LinkDB

KEGG   ORTHOLOGY: K26212
Entry
K26212                      KO                                     
Symbol
K26212
Name
guanosine phosphorylase [EC:2.4.2.15]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01232  Nucleotide metabolism
Module
M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate
Reaction
R02147  guanosine:phosphate alpha-D-ribosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K26212  K26212; guanosine phosphorylase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.15  guanosine phosphorylase
     K26212  K26212; guanosine phosphorylase
Other DBs
COG: COG2820
GO: 0047975
Genes
ALKL: MM271_13185
CLOL: ONV75_11030
CLOO: RCG18_18805
OHI: H8790_09760
GBX: SANA_30400(udp)
MLIY: RYJ27_00540
MICE: EHF32_11800
MICI: AB2L57_00580
RATH: GSU68_14675
MHUM: NNL39_06085
CELE: P9841_15565
DSS: GCM25873_15090
DCP: RN607_03695
JAT: SAMN05892883_1429
HAL: VNG_1850G(udp1)
HSL: OE_3603R(udp3)
HANR: LJ422_07450
HDL: HALDL1_14290
HHB: Hhub_3201(udp2)
HAGS: JT689_08795
HABO: JRZ79_07200
HNO: LT974_12725
HLU: LT972_02155
HANX: ABSL23_01775
HALH: HTSR_1867(udp2)
HHSR: HSR6_1936(udp2)
HSU: HLASF_1913(udp2)
HSF: HLASA_1899(udp2)
HAHS: HSRCO_2534(udp2)
SALR: FQU85_07260
HALR: EFA46_001835
HJE: HacjB3_06485
HDO: MUK72_12005
HALX: M0R89_03335
HAXZ: M0R88_03560
HAYC: NGM10_11185
HAXY: NGM07_08120
SALI: L593_02520
SAIM: K0C01_09950
HARA: AArcS_1086(udp)
HMA: rrnAC3434(udp1)
HSIN: KDQ40_10225
HHI: HAH_0661(udp1)
HHN: HISP_03405
HAB: SG26_11170
HTA: BVU17_03245
HALJ: G9465_16935
HTI: HTIA_1277
HALA: Hrd1104_02285
HASV: SVXHr_1586(udp)
HABN: HBNXHr_1570(udp)
HMU: Hmuk_1527
HALZ: E5139_10760
HALL: LC1Hm_0785(udp)
HAZP: GBQ70_10755
HALI: BV210_12595
HSN: DV733_12730
HDS: HSR122_1654(udp)
HRR: HZS55_02250
HPEL: HZS54_01490
HLT: I7X12_11020
HARC: HARCEL1_04675
SSAI: N0B31_11675
HAAD: MW046_02680
NPH: NP_3180A(udp2)
NMO: Nmlp_2096(udp2)
NHO: HWV23_14725
NSAL: HWV07_17245
HWA: HQ_3201A(udp3)
HWC: Hqrw_3763(udp3)
HVO: HVO_2614(udp2)
HALE: G3A49_16765
HLN: SVXHx_1984(udp2)
HME: HFX_2629(udp)
HGI: ABY42_13120
HLS: KU306_15610
HBO: Hbor_09630
HAQ: DU484_17715
HAJ: DU500_00755
HAER: DU502_16140
HRA: EI982_14800
HLM: DV707_04850
HALM: FCF25_02905
HLA: Hlac_2318
HALP: DOS48_11705
HALB: EKH57_13425
HEZZ: EO776_12905
HALQ: Hrr1229_009230
HSS: J7656_03390
HSAI: HPS36_08730
HAZZ: KI388_11455
SRUB: C2R22_16090
HAE: halTADL_2506
HALN: B4589_007220
HALG: HUG10_01645
HALU: HUG12_15755
HMP: K6T50_15060
HRE: K6T36_15025
HRM: K6T25_01285
HACB: Hbl1158_07170
HDF: AArcSl_2849(udp2)
HAAA: AArcCO_1066(udp)
HAH: Halar_2257
HTU: Htur_0567
HSAL: JMJ58_06280
HAKZ: J0X25_10220
NMG: Nmag_2962(udp2)
HXA: Halxa_1684
NAT: NJ7G_4166
NPE: Natpe_3487
NVR: FEJ81_15950
NPL: FGF80_15035
NAY: HYG81_12615
HALY: HYG82_19655
HJT: DVR14_07570
HLO: J0X27_12280
NGE: Natgr_1137
HLC: CHINAEXTREME02085
HRU: Halru_0721
SAWL: NGM29_17205
HALV: NGM15_08390
NOU: Natoc_0398
HLR: HALLA_07085
NAJ: B1756_00170
NAG: AArcMg_3198
NAN: AArc1_3107
NARA: QQ977_03525
NBG: DV706_08835
NAS: GCU68_03230
HDA: BB347_11110
PABI: PABY_07770
PARE: PYJP_13520
BARC: AOA65_0444
 » show all
Reference
PMID:36434094
  Authors
Sato T, Utashima SH, Yoshii Y, Hirata K, Kanda S, Onoda Y, Jin JQ, Xiao S, Minami R, Fukushima H, Noguchi A, Manabe Y, Fukase K, Atomi H.
  Title
A non-carboxylating pentose bisphosphate pathway in halophilic archaea.
  Journal
Commun Biol 5:1290 (2022)
DOI:10.1038/s42003-022-04247-2
  Sequence
[hla:Hlac_2318] [hal:VNG_1850G]
LinkDB

KEGG   ENZYME: 2.4.2.15
Entry
EC 2.4.2.15                 Enzyme                                 
Name
guanosine phosphorylase
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
guanosine:phosphate alpha-D-ribosyltransferase
Reaction(IUBMB)
guanosine + phosphate = guanine + alpha-D-ribose 1-phosphate [RN:R02147]
Reaction(KEGG)
R02147
Substrate
guanosine [CPD:C00387];
phosphate [CPD:C00009]
Product
guanine [CPD:C00242];
alpha-D-ribose 1-phosphate [CPD:C00620]
Comment
Also acts on deoxyguanosine.
History
EC 2.4.2.15 created 1965
Pathway
ec00230  Purine metabolism
ec01100  Metabolic pathways
Orthology
K26211  guanosine phosphorylase
K26212  guanosine phosphorylase
Genes
SLOM: PXH66_14350
AAQW: K1X11_021490
TOB: V4D31_06360(mtnP)
TAUT: V4D30_01725(mtnP)
NVA: G3M78_03720
BACN: GNK04_07020
ALKL: MM271_13185
ALKG: MOJ78_01200
CLOL: ONV75_11030
CLOO: RCG18_18805
OHI: H8790_09760
NCJ: MCACP_10560(mtnP_2)
BACG: D2962_00915
GBX: SANA_30400(udp)
TIZ: RBU61_10015
SPOK: ACFWUA_01985
LEIZ: IT072_20595
MLIY: RYJ27_00540
MICE: EHF32_11800
MICI: AB2L57_00580
RATH: GSU68_14675
MHUM: NNL39_06085
CELE: P9841_15565
DSS: GCM25873_15090
DCP: RN607_03695
JAT: SAMN05892883_1429
FSH: Q2T83_03560
PFU: PF0853
PFI: PFC_03460
PHO: PH1143(PH1143)
PAB: PAB1659
PYN: PNA2_1750
PYA: PYCH_04740
PYS: Py04_1066
PYC: TQ32_02700
TKO: TK1482
TON: TON_0128
TGA: TGAM_1953(mtaP-2)
TSI: TSIB_1419
TBA: TERMP_00252
THE: GQS_04600
THA: TAM4_95
THM: CL1_0573
TLT: OCC_03713
THS: TES1_0338
TNU: BD01_2216
TEU: TEU_05410
TGY: X802_02715
THV: ADU37_CDS15240
TCH: CHITON_0993
TPEP: A0127_07785
TPIE: A7C91_06585
TGG: A3K92_01065
TCE: A3L02_00285
TBS: A3L01_01345
THH: CDI07_01320(mtnP)
TSL: A3L11_05085
TTD: A3L14_02800
TPRF: A3L09_02815
TRL: A3L10_05235
TPAF: A3L08_04350
THY: A3L12_00855
TIC: FH039_03195(mtnP)
TCQ: TIRI35C_0489
THEM: FPV09_06005(mtnP)
THEI: K1720_10300(mtnP)
TAGG: NF865_04470(mtnP)
PPAC: PAP_07050
HAL: VNG_1850G(udp1)
HSL: OE_3603R(udp3)
HANR: LJ422_07450
HDL: HALDL1_14290
HHB: Hhub_3201(udp2)
HAGS: JT689_08795
HABO: JRZ79_07200
HNO: LT974_12725
HLU: LT972_02155
HANX: ABSL23_01775
HALH: HTSR_1867(udp2)
HHSR: HSR6_1936(udp2)
HSU: HLASF_1913(udp2)
HSF: HLASA_1899(udp2)
HAHS: HSRCO_2534(udp2)
SALR: FQU85_07260
HALR: EFA46_001835
HJE: HacjB3_06485
HDO: MUK72_12005
HALX: M0R89_03335
HAXZ: M0R88_03560
HAYC: NGM10_11185
HAXY: NGM07_08120
SALI: L593_02520
SAIM: K0C01_09950
HARA: AArcS_1086(udp)
HMA: rrnAC3434(udp1)
HSIN: KDQ40_10225
HHI: HAH_0661(udp1)
HHN: HISP_03405
HAB: SG26_11170
HTA: BVU17_03245
HALJ: G9465_16935
HTI: HTIA_1277
HALA: Hrd1104_02285
HASV: SVXHr_1586(udp)
HABN: HBNXHr_1570(udp)
HMU: Hmuk_1527
HALZ: E5139_10760
HALL: LC1Hm_0785(udp)
HAZP: GBQ70_10755
HALI: BV210_12595
HSN: DV733_12730
HDS: HSR122_1654(udp)
HRR: HZS55_02250
HPEL: HZS54_01490
HLT: I7X12_11020
HARC: HARCEL1_04675
SSAI: N0B31_11675
HAAD: MW046_02680
NPH: NP_3180A(udp2)
NMO: Nmlp_2096(udp2)
NHO: HWV23_14725
NSAL: HWV07_17245
HWA: HQ_3201A(udp3)
HWC: Hqrw_3763(udp3)
HVO: HVO_2614(udp2)
HALE: G3A49_16765
HLN: SVXHx_1984(udp2)
HME: HFX_2629(udp)
HGI: ABY42_13120
HLS: KU306_15610
HBO: Hbor_09630
HAQ: DU484_17715
HAJ: DU500_00755
HAER: DU502_16140
HRA: EI982_14800
HLM: DV707_04850
HALM: FCF25_02905
HLA: Hlac_2318
HALP: DOS48_11705
HALB: EKH57_13425
HEZZ: EO776_12905
HALQ: Hrr1229_009230
HSS: J7656_03390
HSAI: HPS36_08730
HAZZ: KI388_11455
SRUB: C2R22_16090
HAE: halTADL_2506
HALN: B4589_007220
HALG: HUG10_01645
HALU: HUG12_15755
HMP: K6T50_15060
HRE: K6T36_15025
HRM: K6T25_01285
HACB: Hbl1158_07170
HDF: AArcSl_2849(udp2)
HAAA: AArcCO_1066(udp)
HAH: Halar_2257
HTU: Htur_0567
HSAL: JMJ58_06280
HAKZ: J0X25_10220
NMG: Nmag_2962(udp2)
HXA: Halxa_1684
NAT: NJ7G_4166
NPE: Natpe_3487
NVR: FEJ81_15950
NPL: FGF80_15035
NAY: HYG81_12615
HALY: HYG82_19655
HJT: DVR14_07570
HLO: J0X27_12280
NGE: Natgr_1137
HLC: CHINAEXTREME02085
HRU: Halru_0721
SAWL: NGM29_17205
HALV: NGM15_08390
NOU: Natoc_0398
HLR: HALLA_07085
NAJ: B1756_00170
NAG: AArcMg_3198
NAN: AArc1_3107
NARA: QQ977_03525
NBG: DV706_08835
NAS: GCU68_03230
HDA: BB347_11110
PABI: PABY_07770
PARE: PYJP_13520
KCR: Kcr_1502
BARC: AOA65_0444
 » show all
Reference
1  [PMID:14008731]
  Authors
YAMADA EW.
  Title
The phosphorolysis of nucleosides by rabbit bone marrow.
  Journal
J Biol Chem 236:3043-6 (1961)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.15
IUBMB Enzyme Nomenclature: 2.4.2.15
ExPASy - ENZYME nomenclature database: 2.4.2.15
BRENDA, the Enzyme Database: 2.4.2.15
CAS: 9030-28-8
LinkDB

KEGG   REACTION: R02147
Entry
R02147                      Reaction                               
Name
guanosine:phosphate alpha-D-ribosyltransferase
Definition
Guanosine + Orthophosphate <=> Guanine + alpha-D-Ribose 1-phosphate
Equation
C00387 + C00009 <=> C00242 + C00620
Reaction class
RC00063  C00242_C00387
Enzyme
2.4.2.1         2.4.2.15
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Module
M00959  Guanine ribonucleotide degradation, GMP => Urate
M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.1
     R02147  Guanosine + Orthophosphate <=> Guanine + alpha-D-Ribose 1-phosphate
    2.4.2.15
     R02147  Guanosine + Orthophosphate <=> Guanine + alpha-D-Ribose 1-phosphate
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.4.2.1
   R08368  N-D-Ribosylpurine <=> Purine
    R02147  Guanosine <=> Guanine
Orthology
K03783  purine-nucleoside phosphorylase [EC:2.4.2.1]
K03784  purine-nucleoside phosphorylase [EC:2.4.2.1]
K05810  purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K09913  purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2]
K26211  guanosine phosphorylase [EC:2.4.2.15]
K26212  guanosine phosphorylase [EC:2.4.2.15]
Other DBs
RHEA: 13236
LinkDB

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