Entry
Name
arginine dihydrolase;
argZ (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
BRITE hierarchy
Sysname
L-arginine aminodihydrolase (L-ornithine-forming)
Reaction(IUBMB)
L-arginine + 2 H2O = L-ornithine + CO2 + 2 ammonia [RN:
R13308 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from different cyanobacterial species, is highly specific to arginine and does not require a metal cofactor. The enzyme from Nostoc is bifunctional, and also catalyses the activity of EC
4.3.1.12 , ornithine cyclodeaminase.
History
EC 3.5.3.27 created 2024
Pathway
ec00330 Arginine and proline metabolism
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
BTAB : 109044769 109044770
CEL : CELE_F38H4.5(F38H4.5) CELE_T22B7.3(T22B7.3) CELE_ZK1307.1(ZK1307.1)
CBR : CBG_01062 CBG_06177 CBG_14718
CRQ : GCK72_003659 GCK72_014187 GCK72_024454
NAI : NECAME_00029 NECAME_10303
REH : H16_A0688(h16_A0688)
RHZ : RHPLAN_25450 RHPLAN_41360
PAUU : E8A73_000505 E8A73_039650
BSED : DN745_11655 DN745_15820
PCAY : FRD00_10315 FRD00_27185
MSAL : DSM43276_03634(arcA_2)
NTP : CRH09_17440 CRH09_29790
NYU : D7D52_17665 D7D52_19685
SANL : KZO11_08940 KZO11_35395
SCYE : R2B67_02060 R2B67_27110
SCB : SCAB_11871 SCAB_78481
SHO : SHJGH_2421 SHJGH_5935
SDV : BN159_4230 BN159_7361
STRE : GZL_02916 GZL_04455
SCZ : ABE83_02190 ABE83_07150 ABE83_21735 ABE83_26645
SLE : sle_58750(sle_58750)
SRN : A4G23_03529 A4G23_04556
STRT : A8713_04080 A8713_08770
SGS : AVL59_10980 AVL59_31560
SPHW : NFX46_23560 NFX46_26405
SNR : SNOUR_12595 SNOUR_19905
SALU : DC74_4436 DC74_6676
SALL : SAZ_23570 SAZ_34695
SVU : B1H20_08265 B1H20_32650
SLX : SLAV_17285 SLAV_25845
STRO : STRMOE7_12210 STRMOE7_21105
SKA : CP970_18575 CP970_31070
SVN : CP980_23470 CP980_30600
SVR : CP971_02015 CP971_03115 CP971_09845 CP971_29685
SPAD : DVK44_07370 DVK44_35395
SFY : GFH48_28610 GFH48_34335 GFH48_36475
SCAV : CVT27_08075 CVT27_31340
SRIM : CP984_09620 CP984_29400
STSU : B7R87_00190 B7R87_08095
SCHA : CP983_20570 CP983_37255
SGX : H4W23_02085 H4W23_04860 H4W23_11490
SBAT : G4Z16_14280 G4Z16_24995
SNF : JYK04_02980 JYK04_04424 JYK04_04430
SPLA : CP981_11435 CP981_20840
SBRO : GQF42_08540 GQF42_30085 GQF42_36655
SDW : K7C20_10795 K7C20_20185
SCAL : I6J39_08440 I6J39_32445
SFB : CP974_19140 CP974_24480
SMOB : J7W19_00310 J7W19_09295
SPEU : CGZ69_30635 CGZ69_34420
SHK : J2N69_09925 J2N69_28750
STRY : EQG64_08170 EQG64_32555
SLF : JEQ17_33050 JEQ17_39820
SDUR : M4V62_00725 M4V62_29580
SYAN : NRK68_10460 NRK68_26220
STAA : LDH80_01665 LDH80_27860
SLON : LGI35_15310 LGI35_39605
SYUN : MOV08_12405 MOV08_19945
SARG : HKX69_08150 HKX69_30235
SJN : RI060_05595 RI060_36585
SHAU : K9S39_12195 K9S39_21790
SROC : RGF97_24585 RGF97_32630
SINN : ABB07_32705 ABB07_39010 ABB07_39665
SARM : DVA86_08655 DVA86_26495 DVA86_28285
STPB : QR97_10695 QR97_20220
SRPA : HEP86_12640 HEP86_21950
SMIB : SMIR_27565 SMIR_34120
STRL : HEP84_10650(ddaH) HEP84_17355(ddaH)
SRPZ : HEP85_06920(ddaH) HEP85_12615(ddaH)
KAB : B7C62_08160 B7C62_31600 B7C62_33865
KAU : B6264_04925 B6264_28705
KIS : HUT16_02780 HUT16_07610
STRH : GXP74_14810 GXP74_27210 GXP74_28730
AGLA : OIE69_27890 OIE69_37490
NARO : CFH99_12080 CFH99_21765
SPIQ : OHA34_06810 OHA34_15765
AJA : AJAP_19615 AJAP_23535 AJAP_36890
AMYB : BKN51_19465 BKN51_19845 BKN51_36950
AMYY : YIM_37965 YIM_44970
AORI : SD37_16145 SD37_38465
AACD : LWP59_02420 LWP59_10720
AROO : NQK81_06750 NQK81_20070
ACYN : ORV05_23000 ORV05_30545
ACOR : LCL61_30000(ddaH) LCL61_41990(ddaH)
ANW : QP939_00785 QP939_09680
PSEE : FRP1_00965 FRP1_28995
PSEH : XF36_00380 XF36_26675
APRE : CNX65_13500 CNX65_32830
ACTU : Actkin_01202 Actkin_05999
STP : Strop_3676 Strop_4529
SAQ : Sare_2147 Sare_4052 Sare_5039
MAU : Micau_5200 Micau_6232
MICB : MicB006_4216 MicB006_6243
MTUA : CSH63_26470 CSH63_31400
MICH : FJK98_27175 FJK98_32625
MTEM : GCE86_20610 GCE86_25245
MCAB : HXZ27_26135 HXZ27_31350
MSAG : GCM10017556_14590 GCM10017556_25420
VMA : VAB18032_04135 VAB18032_29861
MCRA : ID554_13450 ID554_20460
VER : HUT12_27055 HUT12_31790
MENO : Jiend_29200 Jiend_39020
MCHL : PVK74_16230 PVK74_20715
MFEU : H1D33_01475 H1D33_06570
MPRN : Q3V37_07325 Q3V37_11920
MHAW : RMN56_12030 RMN56_16870
MCAY : PVK37_00985 PVK37_05860
MICF : QQG74_26595 QQG74_31235
AMS : AMIS_72610 AMIS_80560
ACTN : L083_7178 L083_8142
ACTS : ACWT_7401 ACWT_8181
AIH : Aiant_33650 Aiant_42100
ACTR : Asp14428_47920 Asp14428_58720
ACTL : L3i22_098530 L3i22_106660
ASIC : Q0Z83_088880 Q0Z83_097370
AOU : ACTOB_007798 ACTOB_008703
ACTE : ACTI_12740 ACTI_20660
PLK : CIK06_23875 CIK06_28650
PLAB : C6361_14205 C6361_18105
PLAT : C6W10_10945 C6W10_30480
PFLA : Pflav_070660 Pflav_081660
PSUU : Psuf_033090 Psuf_044470
PRY : Prubr_25740 Prubr_36120 Prubr_57420
CATI : CS0771_17560 CS0771_20980
DVC : Dvina_00565 Dvina_45590
DFU : Dfulv_00645 Dfulv_40290
DROS : Drose_00545 Drose_15980 Drose_30505
DAUR : Daura_00615 Daura_43895
DMAT : Dmats_00610 Dmats_39955
DACT : KZZ52_00655 KZZ52_21810 KZZ52_51990
CCAZ : COUCH_01345 COUCH_06710
SYY : SYNGTS_2937(sll1336)
SYT : SYNGTI_2936(sll1336)
SYS : SYNPCCN_2935(sll1336)
SYQ : SYNPCCP_2935(sll1336)
SCYS : NIES4073_40490 NIES4073_43750
EDA : GWR55_04335 GWR55_08140
EDG : H7846_10305 H7846_11500
EPL : P4G45_06450 P4G45_07695
TGI : RBB81_12380 RBB81_15965
TEMP : RBB75_16025 RBB75_17710
TPSC : RBB77_13750 RBB77_15865
» show all
Taxonomy
Reference
Authors
Zhang H, Liu Y, Nie X, Liu L, Hua Q, Zhao GP, Yang C.
Title
The cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase.
Journal
Sequence
Reference
Authors
Burnat M, Picossi S, Valladares A, Herrero A, Flores E.
Title
Catabolic pathway of arginine in Anabaena involves a novel bifunctional enzyme that produces proline from arginine.
Journal
Sequence
Reference
Authors
Zhuang N, Zhang H, Li L, Wu X, Yang C, Zhang Y.
Title
Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.3.27
ExPASy - ENZYME nomenclature database: 3.5.3.27
LinkDB
All DBs