KEGG ORTHOLOGY: K28561

ORTHOLOGY: K28561

Entry

K28561                      KO

Symbol

cerR

Name

ceramide reductase [EC:1.-.-.-]

Pathway

map00600

Sphingolipid metabolism

map01100

Metabolic pathways

Reaction

R13564

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K28561  cerR; ceramide reductase

Other DBs

COG:

COG0451

Genes

EOI:	ECO111_3805

EOJ:	ECO26_4084

EOH:	ECO103_3660

ECOO:

ECOH:

ESL:

ESO:

ESM:

ECG:	E2348C_3263

EOK:	G2583_3702

ELH:

ETEC_3251

ECW:	EcE24377A_3443

EUN:	UMNK88_3733

ECP:

ECP_3061

ENA:	ECNA114_3059

ECOS:

EC958_3369

ECV:	APECO1_3444

ECOA:

APECO78_18670

ECX:	EcHS_A3156

ECM:	EcSMS35_3261

ECY:

ECSE_3261

ECR:	ECIAI1_3125

ECQ:	ECED1_3626

ECT:	ECIAI39_3471

EOC:

EBR:

ECOB:

EBL:

EBE:	B21_02802(ybl133)

ECI:	UTI89_C3398

EIH:	ECOK1_3395

ECZ:	ECS88_3358

ECC:

c3713

ELO:	EC042_3266

ELN:	NRG857_14770

ESE:

ECSF_2807

ECL:	EcolC_0717

EKF:	KO11_07795

EAB:	ECABU_c33820

ELU:	UM146_01480

ELW:

ELL:

ELC:

ELD:

ELP:	P12B_c3079

ELF:

ECOL:

ECOI:

ECOJ:

EAL:	EAKF1_ch2972c

ESZ:	FEM44_05940

ERUY:

OSH18_16680

ESF:	ACK8NJ_03675

SFL:

SFX:

SFE:

SFN:

SFS:

SFT:	NCTC1_03276

SDY:

SDY_3089

SHQ:	A0259_18620

SHIG:

LXH19_03795

CAMA:

F384_04865

CAF:	AL524_17405

CFAR:

CI104_09960

CTEL:

GBC03_20310

CENS:

P2W74_14570

CIY:	HAP28_09800

EBT:	EBL_c39870

PGE:	LG71_03155

MPHG:

EBB:

SMAR:

SMAC:

SMW:	SMWW4_v1c32740

SLQ:	M495_15850

SERF:

SERS:

SSUR:

SURI:

SRHZ:

SENP:

SNEM:

SSAR:

SERB:

SERN:

RIU:	I2123_25115

ROU:	AB3G37_05895

SLIG:

GTU79_11410

EBI:

EbC_37160

EPE:	CI789_09590

ERWI:

GN242_08680

ERP:	LJN55_09975

ERWE:

GKQ23_06610

TCI:	A7K98_08105

TATU:

EFZ10_11000

HAV:	AT03_13770

HPAR:

AL518_02605

OPO:	DSM2777_10300

LRZ:	BJI69_19430

LPY:	FIV34_09485

LAEG:

L2Y94_19600

LAEO:

L2Y97_10500

LAES:

L2Y96_03585

PVR:	PverR02_14780

PLUL:

FOB45_16290

PUM:	HGP31_13700

PHOM:

KJF94_11280

PAGB:

AWM79_23535

PBAB:

AAEO81_10780

PKG:	LW136_14805

AVN:	Avin_44260

AVL:	AvCA_44260

AVD:	AvCA6_44260

ACX:

CCHR:

MEIY:

MCAU:

WMA:	WM2015_1721

TTC:	FOKN1_1267

THIC:

TspCOW1_13520

KUY:	FY550_03255

GBI:	PG2T_09055

SALN:

SALB1_2338

AJS:

Ajs_3080

DIJ:	HND92_13480

DIS:	I3K84_21480

XYG:	R9X41_10170

NEU:

NE1657

NET:

Neut_0459

NIT:	NAL212_0308

NII:	Nit79A3_0510

NCO:	AAW31_06250

NUR:	ATY38_04150

NST:	Nstercoris_01231

NMU:	Nmul_A0230

NLC:	EBAPG3_001560

NIZ:	NNRS527_02882

MRK:	FIT61_02725

KMN:	HW532_16950

NOH:	G5V57_01460

CCR:

CC_1164

CCS:	CCNA_01222

CAK:

Caul_1687

CSE:

Cseg_2714

CHQ:	AQ619_07685

CFH:	C1707_13290

CAUF:

CSW63_09130

PZU:

PHZ_c2051

RMM:	ROSMUCSMR3_00100

ROK:	RAK1035_2951

HDH:	G5B40_18785

FRB:	AB6B37_07650

HNE:

ZMO:

ZMN:

ZMM:

ZMB:

ZMI:

ZMC:	A265_01032

ZMR:	A254_01031

ZMP:	Zymop_0957

NAR:

Saro_1147

NPP:	PP1Y_AT7613

NPN:	JI59_14445

NRE:	BES08_09665

NOV:	TQ38_013775

NOT:	C7W88_09875

NOR:	FA702_15180

NGF:	FRF71_01280

NOG:	GKE62_02450

NDR:	HT578_19060

NHUM:

PQ457_03600

NOL:	NSDW_27180

NCP:	U0041_07605

NOVO:

NOVB:

SPHM:

STAX:

SPHI:

SSAN:

SNJ:	A7E77_12760

SMY:	BJP26_17735

SPAN:

AWL63_08575

SKR:	BRX40_18960

SPLM:

SPLK:

SPKC:

SPHC:

SPHF:

SPHA:

SPAU:

SLUT:

SRHI:

SLAN:

SDH:	H9L15_15275

SSED:

H9L14_01885

SPAP:

H3Z74_04930

SXA:	FMM02_07720

SPAI:

SPII:

SSIN:

SSAU:

SARI:

SCHY:

SSUA:

SBIN:

SAER:

SMOR:

SGLC:

SQO:	NMP03_07890

SCAB:

SRAD:

SHAN:

SNAP:

SNOS:

SDON:

SSAG:

SABI:

SAAP:

SPNB:

SPCL:

SPRR:

SPMB:

SPSO:

CIJ:	WG74_07690

SPHJ:

ACOB:

SSAA:

SPZR:

ACOA:

SAL:

SPHK:

SPHP:

SMAG:

SMAZ:

STER:

SGI:	SGRAN_0942

SPHQ:

SPHO:

SPHX:

SINA:

SPEG:

SPFD:

SPBS:

SPUS:

SPOG:

SPYF:

SPJJ:

SPHU:

SWI:

SPHD:

SJP:	SJA_C1-27260

SINB:

SIDU_01200

SCH:	Sphch_2997

SYB:	TZ53_13920

SBD:	ATN00_09620

SPMI:

SPHB:

SPHR:

SPHT:

SHYD:

SYA:	A6768_14800

SCLO:

SPYG:

SUFL:

SBAR:

SAMI:

SPPH:

SPAG:

SPCA:

SPRS:

SPJS:

SPWT:

SPTA:

SPHG:

SFLA:

SPHY:

SPHL:

SLAA:

PARJ:

PHAO:

BLAS:

BFW:	B5J99_09445

PALG:

PARP:

SFLV:

SMAT:

SMIC:

SPHS:

SAND:

POQ:	KZX46_12805

PMEA:

KTC28_10650

AEP:	AMC99_01847

ALB:

AEB_P3236

ALH:	G6N82_12780

ARUE:

ALTN:

ALTC:

AAY:

AMX:	AM2010_451

PMAS:

NCF86_02315

ANH:	A6F65_02247

ADO:	A6F68_01518

TFV:	IDJ81_07840

CNA:	AB433_13120

CMAN:

A9D14_08845

ERY:	CP97_12025

EGN:	BMF35_a0163

EFV:	CHH26_05145

QCI:	NCF85_09870

QSP:	L1F33_06030

QSO:	IRL76_02245

QAR:	K3148_09140

QGE:	K3136_04935

QPS:	K3166_02795

QXI:	K3162_05055

QPR:	SD421_07570

ELI:

ELI_01865

ELQ:	Ga0102493_11180

ERK:	CD351_06200

ERR:	DVR09_13040

ERF:	FIU90_05980

EMV:	HQR01_01280

PNS:	A9D12_08985

ERYT:

KDC96_08750

ERYZ:

F7D01_02880

ERYS:

LY632_12370

ERQ:	PS060_10390

PORL:

BG023_111307

PHZ:	CHX26_07125

POT:	E2E27_15480

PORC:

CBR61_06655

NTD:	EGO55_13335

CAEN:

AFLV:

BMAA:

PAUI:

EBK:	PF049_05705

GBE:	GbCGDNIH1_0241

GBH:	GbCGDNIH2_0241

GBC:	GbCGDNIH3_0241

GBS:	GbCGDNIH4_0241

LCK:	HN018_18585

ACIM:

GT370_16800

RGI:	RGI145_20075

ROS:	CTJ15_01695

RMUC:

FOB66_02615

RMT:	IAI58_21610

SHUM:

STHU_10730

SVC:	STVA_11280

NAO:	Y958_26645

NCB:	C0V82_06325

RCE:

RC1_0746

DVN:	HQ394_11020

AALU:

ABWI00_08175

HTQ:	FRZ44_23730

HADH:

FRZ61_23470

MVP:	P4R82_13160

HFL:	PUV54_05770

HFO:	ABFZ83_11680

ECOG:

FIV45_09685

PAQI:

KW060_04210

KOZ:	KFF44_06905

TMK:	QGN29_10170

GSO:	PH603_11790

HMR:	Hipma_0804

GBZ:	JZM60_05915

GEB:

GM18_2753

PPD:

Ppro_2769

DDS:

Ddes_2202

DFI:	AXF13_14675

DPG:	DESPIGER_2010

DEF:	CNY67_01060

DTR:

DAMI:

DELF:

PMEN:

DSF:

DML:	Dmul_13470

DTI:	Desti_2323

DAX:	FDQ92_11605

DAW:	HS1_001252

AFW:	Anae109_1215

AORY:

AMOR_09120

APAU:

AMPC_34750

MXA:

MXAN_3746

MSD:	MYSTI_04191

MFB:	MFUL124B02_22540

MLAN:

JY572_05710

MFAE:

VZP55_32005

MVH:	ACN6A1_17795

MYM:	A176_003188

PFLY:

VZL07_34350

CCX:	COCOR_01541

MFU:	LILAB_01125 LILAB_26905

MMAS:

MYMAC_001647 MYMAC_003695

CEXI:

ACN6A2_09475

PPAK:

JY651_15375

SUR:	STAUR_4245

AGE:	AA314_03058

AVM:	JQX13_00880

MBD:	MEBOL_007676

CFUS:

CYFUS_002224

VIN:	AKJ08_0309

PBRU:

PRUE:

PALJ:

SCL:

SCU:	SCE1572_42010

SORG:

NQZ70_08552(oleD_2)

CCRO:

CMC5_057060

PAUU:

E8A73_018895 E8A73_021595

MRM:	A7982_08873

PABO:

BCY86_07500

SAMY:

DB32_006363

LLU:	AKJ09_02660

NANN:

O0S08_18810

HAX:	BALOs_1232

BSTO:

C0V70_07320

FPES:

NXS98_00065

MFF:	MFFC18_04740(tal)

ROL:	CA51_37580

AAGG:

ETAA8_67650

RLC:	K227x_22160

SMAM:

Mal15_57420(tal_3)

SNEP:

Enr13x_25620(rmlD_2)

SMAE:

TBK1r_24870(tal_2)

TTF:

THTE_3361

LPAV:

PLANPX_0151

LLH:

I41_02380

AMUC:

Pan181_36280(tal_1)

PND:	Pla175_46480 Pla175_51500(rmlD)

AMOB:

HG15A2_06190(rmd)

BMEI:

Spa11_38580

BGOK:

Pr1d_52450

CCOP:

Mal65_48410(tal_2)

HBS:	IPV69_02260

SUS:

Acid_5451

MSIL:

METEAL_24820

MSEA:

METESE_21170

EPM:	Dip510_001069

PPRX:

EPO:

ETI:

RSD:

GBA:

BTH:

BTHO:

Btheta7330_00043(rfbB)

BFR:

BF4568

BFS:	BF9343_4240

BFG:	BF638R_4515

BFB:	VU15_21205

BHL:	Bache_0795

BXY:

BXY_21630

BOA:	Bovatus_03134(rfbB_3)

BCEL:

BcellWH2_02955(rmd_2)

BCAC:

CGC64_03205

BCAE:

A4V03_17875

BZG:	C4H11_09665

BHF:	C3V43_08665

BIS:	DXK01_005585

BUN:	Bun01g_06550

BEG:	INE88_01847(rfbB_1)

BSTE:

K6V31_10440

BFE:	K6V30_04095

BNO:	K8P02_17870

BHUM:

JXR92_003580

BFC:	BacF7301_04210

BSAL:

K6V25_03825

BFIN:

BFINE_13010

BACE:

H1A11_15240

BDS:	ACNOGP_04750

BZA:	ACNOHN_04995

BVU:

BVU_1089

BSA:	Bacsa_2460

BDO:	EL88_24640

BDH:	GV66_06315

PCOP:

I6J50_15045

PGI:

PG_1954

PGN:

PGN_1886

PGT:	PGTDC60_0227

PCRE:

NCTC12858_00041

PCAG:

NCTC12856_00877(rmlD_2)

PEND:

LA319_07190

PORP:

J4862_06505

PBT:	ING2E5B_1901

PMUC:

ING2E5A_0639

PET:	PEIBARAKI_6734

PSAC:

PSM36_2531

PROJ:

KDN43_07370

DYS:	G7050_09255

DYH:	G7051_09595

LFG:	ABNK31_15260

PDI:

BDI_3083

PARC:

CI960_21610

PMER:

INE87_02518(gnu)

PGOL:

K6V26_20200

PJO:	LK449_17075

PFAI:

NXY11_19105

PABC:

NEE14_012680

TFO:

BFO_2645

TOH:	BCB71_02465

PARY:

A4V02_11520

MGOD:

E7746_12455

DUN:	FDZ78_07125

DDB:	E7747_05620

DUQ:	E7745_03415

BVS:	BARVI_07710

COPR:

Cop2CBH44_23450

CFAS:

Cfast33896_17790

PMZ:	HMPREF0659_A6406

PDN:	HMPREF9137_0540

PIT:	PIN17_A0576

PDT:	Prede_1377

PRO:	HMPREF0669_00760

PFUS:

ADJ77_06530

PJE:	CRM71_08360

PNI:	J5A59_04160

PMUF:

J4864_05255

PHIS:

J5A62_00165

PHER:

prwr041_10550

PVF:	J5A55_00060

PSCJ:

PCOU:

PBIV:

PRU:

PCOI:

POC:	NCTC13071_00544(galE_1)

PBY:	L6471_04405

SHOI:

KUA50_011345

SBAO:

L6469_09130

PEO:	AS203_00925

PBUC:

LK429_03235

ALQ:	C7Y71_007445

PCLR:

PC1C4_05430

HLAM:

K4L44_10720

HXY:	K5X82_16450

CPI:

CHIH:

CFIL:

CSAC:

NKO:	Niako_1293

FGG:	FSB75_09200

ARB:	A9P82_14975

AGI:	FSB73_17580

ATEE:

K9M52_16455

PSEG:

D3H65_09885

SEDT:

TEGAF0_19920

AUP:	AsAng_0063880

PHE:

Phep_2197

PEP:	AQ505_14280

PCM:	AY601_0808

PSTY:

BFS30_23570

PGS:	CPT03_07945

PEK:	FFJ24_013955

PROE:

H9L23_13405

PRK:	H9N25_13235

PGJ:	QG516_01115

PEV:	KYH19_12925

PEDO:

AB3G38_08440

SHT:	KO02_19345

SPHN:

BV902_24810

SMIZ:

4412673_03177(rffG)

SPSC:

SPHZ:

SPHE:

SPDR:

SDJ:	NCTC13534_04497

STHA:

SSPI:

SMUI:

SSIY:

SFAE:

SBAM:

SOP:	PQ465_05205

SPRZ:

SPAY:

MUC:

MGOT:

MUH:	HYN43_004640

MGK:	FSB76_21450

MRUB:

MGOS:

MMAB:

MGIK:

MDJ:	LLH06_12440

MJJ:	PQO05_15045

MSAB:

SNE25_25140

MUY:	SNE26_03965

SBX:	CA265_13570

LBY:

Lbys_0493

DFE:

Dfer_2555

DSN:	HWI92_24745

DYC:	NFI80_24650

DFQ:	NFI81_25740

DCN:	MUK70_30255

DPF:	ON006_17010

DEND:

ACN9ML_15095

RSI:	Runsl_0886

RUN:	DR864_13555

RUP:	DTQ70_27070

PKO:	PKOR_15445

PACT:

CA264_07030

PONT:

C1N53_04000

IRO:	RT717_07990

IMP:	ACMVP2_22985

CHK:	D4L85_19545

RCG:	N7E81_02525

SHYR:

LA303_05535

CTE:

CT1949

CPC:

Cpar_0265

CLZ:	BIU88_10560

CCH:

Cag_0225

CPH:	Cpha266_2305

CPB:	Cphamn1_2202

CLI:

PVI:

PLT:

PPH:

PAA:

PROC:

PRS:	B9H02_09850

PROS:

PROW:

PROI:

CTS:

RMR:

RMG:	Rhom172_2569

RLO:	GQ464_010965

SRU:

SRM:

IAL:

MRO:

CPRV:

CACI:

FML:	FMIA91_04940

CABY:

Cabys_2750

TYE:	THEYE_A0593

TOB:	V4D31_02745

TAUT:

V4D30_00330

DTP:	JZK55_08080

NALL:

PP769_00285

NNEO:

PQG83_11475

NLI:	G3M70_12535

NWT:	NSPWAT_1052

NVA:	G3M78_05950

BSED:

DN745_01160

PCAY:

FRD00_21000

SGM:	GCM10017557_77540

SGZ:	C0216_32120

SRK:	FGW37_31645

STSU:

B7R87_18225

SVD:	CP969_01110

SGOB:

test1122_07150

AGLA:

OIE69_11720

PSEI:

GCE65_04465

NGV:	CDO52_03760

NOA:	BKM31_23010

NOW:	GBF35_49135

NGN:	LCN96_24015

NFS:	OIE67_23795

RRD:	RradSPS_2789

LEPV:

J4558_03180

MOX:

DAMO_3067

» show all

Reference

PMID:34969973

Authors

Stankeviciute G, Tang P, Ashley B, Chamberlain JD, Hansen MEB, Coleman A, D'Emilia R, Fu L, Mohan EC, Nguyen H, Guan Z, Campopiano DJ, Klein EA.

Title

Convergent evolution of bacterial ceramide synthesis.

Journal

Nat Chem Biol 18:305-312 (2022)
DOI:10.1038/s41589-021-00948-7

Sequence

[ccs:CCNA_01222] [pgn:PGN_1886] [mxa:MXAN_3746] [bsto:C0V70_07320]

LinkDB

REACTION: R13564

Entry

R13564                      Reaction

Definition

Oxidized ceramide <=> Dihydroceramide

Equation

C23072 <=> C12126

Comment

ceramide reductase

Enzyme

1.-.-.-

Pathway

rn00600

Sphingolipid metabolism

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.-
   1.-.-
    1.-.-.-
     R13564  Oxidized ceramide <=> Dihydroceramide

Orthology

K28561

ceramide reductase [EC:1.-.-.-]

LinkDB

DBGET integrated database retrieval system