| Entry |
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| Name |
Avermectin biosynthesis, 2-methylbutanoyl-CoA/isobutyryl-CoA => 6,8a-Seco-6,8a-deoxy-5-oxoavermectin 1a/1b aglycone => avermectin A1a/B1a/A1b/B1b
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| Definition |
K14371+K24567+K24568+K24569 K14372 K14373 K14374 K14375
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| Diagram |
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| Orthology |
aveA; avermectin polyketide synthase AveA [RN: R06481 R06483] aveE; cytochrome P450 hydroxylase [EC:1.14.-.-] [RN: R06467 R06470] aveD; avermectin B 5-O-methyltransferase [EC:2.1.1.-] [RN: R06477 R06479] |
|---|
| Class |
Pathway modules; Biosynthesis of terpenoids and polyketides; Macrolide biosynthesis
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|---|
| Pathway |
| map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
| map01110 | Biosynthesis of secondary metabolites |
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| Reaction |
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|---|
| Compound |
| C11977 | 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone |
| C11978 | 5-Oxoavermectin ''1a'' aglycone |
| C11979 | Avermectin B1a aglycone |
| C11980 | Avermectin A1a aglycone |
| C11982 | Avermectin A1a monosaccharide |
| C11981 | Avermectin B1a monosaccharide |
| C11961 | 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone |
| C11962 | 5-Oxoavermectin ''1b'' aglycone |
| C11963 | Avermectin B1b aglycone |
| C11964 | Avermectin A1b aglycone |
| C11966 | Avermectin A1b monosaccharide |
| C11965 | Avermectin B1b monosaccharide |
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| LinkDB |
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