KEGG   PATHWAY: map00350Help
Entry
map00350                    Pathway                                

Name
Tyrosine metabolism
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
map00350  Tyrosine metabolism
map00350

Ortholog table
Module
M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:map00350]
M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:map00350]
M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:map00350]
M00533  Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:map00350]
Disease
H00163  Alkaptonuria
H00165  Tyrosinemia
H00168  Oculocutaneous albinism
H00251  Thyroid dyshormonogenesis
H00548  Brunner syndrome
H00831  Primary dystonia
H01005  Dopamine beta-hydroxylase deficiency
H01161  Aromatic L-amino acid decarboxylase deficiency
Other DBs
GO: 0006570
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
map00020  Citrate cycle (TCA cycle)
map00360  Phenylalanine metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00620  Pyruvate metabolism
map00621  Dioxin degradation
map00650  Butanoate metabolism
map00940  Phenylpropanoid biosynthesis
map00950  Isoquinoline alkaloid biosynthesis
KO pathway
ko00350   
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