Entry |
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Name |
Arachidonic acid metabolism
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Class |
Metabolism; Lipid metabolism
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Pathway map |

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Disease |
H00490 | Diaphyseal dysplasia with anemia |
H02284 | Leukotriene C4 synthase deficiency |
H02440 | Fleck retina, familial benign |
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Other DBs |
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Reference |
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Authors |
Spector AA, Fang X, Snyder GD, Weintraub NL. |
Title |
Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function. |
Journal |
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Reference |
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Authors |
Harman CA, Rieke CJ, Garavito RM, Smith WL. |
Title |
Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid. |
Journal |
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Reference |
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Authors |
Poloyac SM, Tortorici MA, Przychodzin DI, Reynolds RB, Xie W, Frye RF, Zemaitis MA. |
Title |
The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney. |
Journal |
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Reference |
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Authors |
Chuang SS, Helvig C, Taimi M, Ramshaw HA, Collop AH, Amad M, White JA, Petkovich M, Jones G, Korczak B. |
Title |
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. |
Journal |
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Reference |
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Authors |
Sacerdoti D, Gatta A, McGiff JC. |
Title |
Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology. |
Journal |
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Reference |
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Authors |
Pfister SL, Spitzbarth N, Zeldin DC, Lafite P, Mansuy D, Campbell WB. |
Title |
Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450. |
Journal |
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Reference |
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Authors |
Fleming I. |
Title |
Cytochrome p450 and vascular homeostasis. |
Journal |
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Reference |
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Authors |
Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL, Zeldin DC. |
Title |
Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain. |
Journal |
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Reference |
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Authors |
Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC, Goldstein JA. |
Title |
CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract. |
Journal |
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Reference |
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Authors |
Pfister SL, Spitzbarth N, Nithipatikom K, Edgemond WS, Falck JR, Campbell WB. |
Title |
Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. |
Journal |
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Related pathway |
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KO pathway |
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LinkDB |
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