Entry |
|
Name |
HSV ICP27 to Nuclear export of mRNA
|
Definition |
ICP27 -| SRPK1 -> SRSF1 == NXF1 |
Expanded |
K19443 -| 6732 -> 6426 == 10482 |
Class |
nt06168 Herpes simplex virus 1 (HSV-1)
|
Type |
Pathogen
|
Pathway |
hsa05168 | Herpes simplex virus 1 infection |
|
Disease |
H00365 | Herpes simplex virus infection |
|
Gene |
6732 | SRPK1; SRSF protein kinase 1 |
6426 | SRSF1; serine and arginine rich splicing factor 1 |
10482 | NXF1; nuclear RNA export factor 1 |
|
Perturbant |
K19443 (ICP27) | UL54; Simplexvirus mRNA export factor |
|
Reference |
|
Authors |
Sandri-Goldin RM |
Title |
The many roles of the regulatory protein ICP27 during herpes simplex virus infection. |
Journal |
|
Reference |
|
Authors |
Sciabica KS, Dai QJ, Sandri-Goldin RM |
Title |
ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation. |
Journal |
|
Reference |
|
Authors |
Sandri-Goldin RM |
Title |
Viral regulation of mRNA export. |
Journal |
|
LinkDB |
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