NETWORK: N00861
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Entry
N00861 Network
Name
Yersinia YopP/J to TLR2/4-NFKB signaling pathway
Definition
YopP/J -| NFKBIA
Expanded
K08598 -| 4792
Class
nt06121
TLR signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05135
Yersinia infection
Disease
H00297
Plague
H00298
Yersiniosis
Gene
4792
NFKBIA; NFKB inhibitor alpha
Perturbant
K08598
(YopP/J)
yopJ; YopJ protease family
Reference
PMID:
16301742
Authors
Zhou H, Monack DM, Kayagaki N, Wertz I, Yin J, Wolf B, Dixit VM
Title
Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation.
Journal
J Exp Med 202:1327-32 (2005)
DOI:
10.1084/jem.20051194
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