| Entry |
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| Name |
Shigella OspG to TNF-NFKB signaling pathway
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| Definition |
OspG -| (UBE2D2+(RBX1+CUL1+SKP1)+FBXW1/11) -> NFKBIA |
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| Expanded |
K13792 -| (7322+(9978+8454+6500)+(23291,8945)) -> 4792 |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 7322 | UBE2D2; ubiquitin conjugating enzyme E2 D2 |
| 6500 | SKP1; S-phase kinase associated protein 1 |
| 23291 | FBXW11; F-box and WD repeat domain containing 11 |
| 8945 | BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase |
| 4792 | NFKBIA; NFKB inhibitor alpha |
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| Perturbant |
| K13792 (OspG) | ospG; secreted effector OspG |
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| Reference |
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| Authors |
Kim DW, Lenzen G, Page AL, Legrain P, Sansonetti PJ, Parsot C |
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| Title |
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes. |
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| Journal |
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| LinkDB |
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