| Entry |
|
|---|
| Name |
Mutation-caused aberrant Htt to electron transfer in Complex II
|
|---|
| Definition |
HTT* -| CxII -> QH2 |
|---|
| Expanded |
3064v1 -| (6389+6390+6391+6392) -> C00390 |
|---|
| Class |
|
|---|
| Type |
Variant
|
|---|
| Pathway |
|
|---|
| Disease |
|
|---|
| Gene |
| 6389 | SDHA; succinate dehydrogenase complex flavoprotein subunit A |
| 6390 | SDHB; succinate dehydrogenase complex iron sulfur subunit B |
| 6391 | SDHC; succinate dehydrogenase complex subunit C |
| 6392 | SDHD; succinate dehydrogenase complex subunit D |
|
|---|
| Variant |
|
|---|
| Metabolite |
|
|---|
| Reference |
|
|---|
| Authors |
Bossy-Wetzel E, Petrilli A, Knott AB |
|---|
| Title |
Mutant huntingtin and mitochondrial dysfunction. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Gu M, Gash MT, Mann VM, Javoy-Agid F, Cooper JM, Schapira AH |
|---|
| Title |
Mitochondrial defect in Huntington's disease caudate nucleus. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Labbadia J, Morimoto RI |
|---|
| Title |
Huntington's disease: underlying molecular mechanisms and emerging concepts. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Mochel F, Haller RG |
|---|
| Title |
Energy deficit in Huntington disease: why it matters. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
