KEGG   NETWORK: N01157
Entry
N01157                      Network                                
Name
Mutation-caused aberrant FUS to FUS-regulated splicing
Definition
mRNA(pre) -- FUS* // mRNA
  Expanded
C00046 -- 2521v1 // C00046
Class
nt06424 RNA processing
nt06464 Amyotrophic lateral sclerosis
Type
Variant
Pathway
hsa05014  Amyotrophic lateral sclerosis
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
Gene
2521  FUS; FUS RNA binding protein
Variant
2521v1 (FUS*)  FUS mutation
Metabolite
C00046  RNA
C00046  RNA
Reference
  Authors
Shang Y, Huang EJ
  Title
Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis.
  Journal
Brain Res 1647:65-78 (2016)
DOI:10.1016/j.brainres.2016.03.036
Reference
  Authors
Zhao M, Kim JR, van Bruggen R, Park J
  Title
RNA-Binding Proteins in Amyotrophic Lateral Sclerosis.
  Journal
Mol Cells 41:818-829 (2018)
DOI:10.14348/molcells.2018.0243
Reference
  Authors
Butti Z, Patten SA
  Title
RNA Dysregulation in Amyotrophic Lateral Sclerosis.
  Journal
Front Genet 9:712 (2018)
DOI:10.3389/fgene.2018.00712
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